2-benzofuran-1,3-dione

2-benzofuran-1,3-dione is an organic chemical compound with the molecular formula C8H4O3 and CAS number 85-44-9. Also known as phthalic anhydride, it is a white crystalline solid with a molecular weight of 148.11 g/mol. This aromatic anhydride belongs to the class of cyclic acid anhydrides and is characterized by its benzofuran ring structure with two carbonyl groups, making it highly reactive in chemical synthesis applications.

2-benzofuran-1,3-dione appears as white crystalline needles or flakes at room temperature. It has a characteristic acrid odor and sublimes readily upon heating. The compound is sparingly soluble in cold water but hydrolyzes to form phthalic acid. It demonstrates good solubility in organic solvents such as alcohol, ether, and acetone. Its melting point is approximately 131°C, and it exhibits high reactivity due to its anhydride functional groups.

2-benzofuran-1,3-dione serves as a crucial intermediate in the production of phthalate plasticizers, polyester resins, and alkyd resins used in paints and coatings. It is extensively utilized in the manufacture of polyethylene terephthalate (PET) plastics and unsaturated polyester resins for fiberglass applications. Additionally, it finds applications in the pharmaceutical industry as a synthetic intermediate and in the production of dyes, pigments, and flame retardants.

2-benzofuran-1,3-dione requires careful handling due to its classification as Acute Tox. 4, Skin Irrit. 2, Eye Dam. 1, Resp. Sens. 1, and Skin Sens. 1. Essential PPE includes respiratory protection with P2 filters, chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction to prevent inhalation. Avoid skin and eye contact, and ensure emergency eyewash stations are accessible. Handle with non-sparking tools and ground equipment properly.

2-benzofuran-1,3-dione should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers away from moisture as the compound hydrolyzes in the presence of water. Store separately from bases, alcohols, and strong oxidizing agents to prevent unwanted reactions. Maintain storage temperatures below 25°C and ensure adequate ventilation to prevent vapor accumulation in storage areas.

Skin contact with 2-benzofuran-1,3-dione requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. For eye contact, rinse immediately with copious amounts of water for at least 15 minutes and seek immediate medical attention due to its Eye Dam. 1 classification. If inhaled, move to fresh air immediately. In case of ingestion, rinse mouth and seek medical attention. Never induce vomiting and provide fresh air in all exposure scenarios.

2-benzofuran-1,3-dione disposal must comply with local and national hazardous waste regulations as it is classified as hazardous waste. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may be neutralized carefully with sodium bicarbonate solution under controlled conditions by trained personnel. Never dispose of this chemical in regular waste streams, sewers, or water bodies. Maintain proper documentation of disposal activities and follow waste tracking requirements.

2-benzofuran-1,3-dione is classified under ADR Class 8 (corrosive substances), Packing Group III for transportation purposes. It requires appropriate UN-specification packaging and proper hazard labeling including corrosive substance markings. Transport documentation must include proper shipping name, UN number, and emergency response information. Vehicles must carry appropriate emergency equipment, and drivers require ADR certification. Ensure packages are secured against movement and protected from moisture during transport.

2-benzofuran-1,3-dione is subject to REACH regulation requiring registration for manufacture or import above one tonne per year in the EU. It must be classified and labeled according to CLP regulation with GHS07, GHS05, and GHS08 pictograms and 'Danger' signal word. While not currently listed as SVHC, it requires safety data sheets for professional users and is subject to occupational exposure limits in many jurisdictions. Transport regulations under ADR also apply.

2-benzofuran-1,3-dione is available through OYSI, a specialized European chemical distributor offering professional-grade chemicals to industrial customers. OYSI provides this compound with full regulatory compliance including proper CLP labeling, safety data sheets, and ADR-compliant packaging for safe transport. As a professional chemical supplier, OYSI ensures product quality and regulatory conformity for European customers requiring this important industrial intermediate for their manufacturing processes.