Nitromethane

CH3NO2

nitromethane

CAS75-52-5
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
75-52-5
EC Number
200-876-6
UN Number
1261
Index Number
609-036-00-7
PubChem CID
6375

Physical-chemical properties

Molecular Formula
CH3NO2
Molar Mass
61.04 g/mol
IUPAC Name
nitromethane

Chemical Identifiers

InChI
InChI=1S/CH3NO2/c1-2(3)4/h1H3
InChI Key
LYGJENNIWJXYER-UHFFFAOYSA-N

Overview

Nitromethane (CAS 75-52-5) is an organic nitro compound with high solvent power and explosive properties when concentrated. This simplest nitroalkane serves as a versatile chemical intermediate and specialty solvent in various industrial applications. With its molecular formula CH3NO2 and molecular weight of 61.04 g/mol, nitromethane exhibits unique characteristics that make it valuable across multiple sectors. The compound appears as a colorless, oily liquid with a distinctive fruity odor and demonstrates excellent miscibility with many organic solvents while showing limited water solubility. From a safety perspective, nitromethane requires careful handling due to its classification as a flammable liquid (Category 3) and acute toxicity concerns (Category 4). The substance carries GHS02 and GHS07 pictograms with a "Warning" signal word, reflecting its fire hazard and potential health risks. Under ADR regulations, it falls under Class 3 dangerous goods, necessitating appropriate transport precautions. Unlike more commonly used solvents such as cyclohexanone or 4-methoxy-4-methylpentan-2-one, nitromethane's nitro functionality provides unique reactivity patterns. Key industrial applications include its use as a solvent for cellulose compounds, synthetic resins, and waxes. The chemical industry utilizes nitromethane as an intermediate in pharmaceutical synthesis and agricultural chemical production. Additionally, it serves specialized applications in fuel formulations and as a reagent in organic synthesis reactions, particularly in nitroaldol condensations and other carbon-carbon bond forming reactions. OYSI supplies high-quality nitromethane to European industrial customers, ensuring reliable availability for technical applications across various industry sectors.

Safety & Classification

Warning
Classification:

Flam. Liq. 3; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1261
ADR Class3
Packing GroupII
Tunnel CodeE
Proper Shipping NameNitromethan
Marine PollutantNo

Frequently Asked Questions

What is nitromethane?

Nitromethane is an organic chemical compound with the molecular formula CH3NO2 and a molecular weight of 61.04 g/mol. It belongs to the nitroalkane family and is classified as a flammable liquid with acute toxicity properties. This colorless liquid is characterized by its distinctive chemical structure containing a nitro group attached to a methyl group, making it a versatile industrial solvent and chemical intermediate.

What are the physicochemical properties of nitromethane?

Nitromethane is a colorless, oily liquid with a characteristic fruity odor at room temperature. It has a boiling point of 101°C and is highly polar, making it miscible with water and many organic solvents. The compound has a density of approximately 1.14 g/cm³ and exhibits relatively high dielectric constant properties. Its chemical stability and solvent properties make it valuable in various applications.

What is nitromethane used for?

Nitromethane serves primarily as an industrial solvent, particularly for cellulose compounds, resins, waxes, fats, and dyes. It functions as a chemical intermediate in pharmaceutical synthesis and organic chemistry reactions. Additionally, it's used in specialized applications such as rocket propellants, racing fuel additives, and as a reagent in analytical chemistry. Its unique properties make it valuable in research and industrial manufacturing processes.

How to handle nitromethane safely?

Nitromethane requires careful handling due to its flammable and toxic properties (GHS02, GHS07 pictograms). Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas away from ignition sources, heat, and open flames. Avoid inhalation and skin contact. Use proper grounding techniques when transferring the liquid to prevent static electricity buildup.

How to store nitromethane correctly?

Nitromethane must be stored in cool, dry, well-ventilated areas away from heat sources, ignition sources, and direct sunlight. Keep containers tightly closed in original packaging. Store separately from strong oxidizing agents, strong bases, and metals. Maintain storage temperatures below 25°C when possible. Ensure storage areas have appropriate fire suppression systems and are equipped with spill containment measures.

What to do in case of contact with nitromethane?

In case of skin contact with nitromethane, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical attention if breathing difficulties occur. For eye contact, rinse immediately with plenty of water for 15 minutes and remove contact lenses if present. Seek immediate medical attention for any significant exposure.

How to dispose of nitromethane appropriately?

Nitromethane disposal must comply with local and national hazardous waste regulations. Never dispose of it down drains or into the environment. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may be disposed of through controlled incineration at authorized facilities. Always consult local environmental authorities for specific disposal requirements and maintain proper waste documentation.

How to transport nitromethane?

Nitromethane is classified under ADR Class 3 (flammable liquids), Packing Group II, requiring specialized transport procedures. It must be transported in UN-approved packaging with proper labeling and documentation. Vehicle operators need ADR certification, and transport vehicles must carry appropriate emergency equipment. Shipping papers must include proper shipping names, hazard classes, and emergency contact information according to dangerous goods regulations.

Is nitromethane subject to specific regulations?

Nitromethane is regulated under various European legislation including CLP Regulation for classification and labeling, and REACH Regulation for chemical registration. It's not currently listed as a Substance of Very High Concern (SVHC). Companies must comply with safety data sheet requirements, workplace exposure limits, and proper hazard communication. Some countries may have additional restrictions on purchase quantities due to security concerns.

Where to buy nitromethane in Europe?

Nitromethane is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI provides nitromethane with proper documentation, safety data sheets, and regulatory compliance for industrial customers across Europe. Contact OYSI directly for availability, specifications, and delivery options. Purchases typically require business credentials and compliance with local regulations regarding hazardous chemical procurement.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.