Naphthalen-2-amine;hydrochloride

Naphthalen-2-amine hydrochloride is an organic chemical compound with the molecular formula C10H10ClN and CAS number 612-52-2. This aromatic amine salt has a molecular weight of 179.64 g/mol and is classified as a Category 1A carcinogen, making it a substance of significant health concern. It belongs to the naphthalene derivative family and requires strict handling protocols due to its hazardous properties.

Naphthalen-2-amine hydrochloride is typically a crystalline solid at room temperature with characteristic aromatic properties. As a hydrochloride salt of an aromatic amine, it generally exhibits better water solubility compared to its free base form. The compound's molecular structure consists of a naphthalene ring system with an amino group, forming a stable salt with hydrochloric acid.

Naphthalen-2-amine hydrochloride is primarily used as an intermediate in chemical synthesis and research applications. It serves as a precursor for dye manufacturing, pharmaceutical intermediates, and various organic synthesis processes. Due to its carcinogenic classification, its industrial applications are heavily regulated and limited to specialized chemical processes where proper safety measures can be implemented.

Safe handling of naphthalen-2-amine hydrochloride requires comprehensive personal protective equipment including respiratory protection, chemical-resistant gloves, and protective clothing. Work must be conducted in well-ventilated areas or under fume hoods due to its carcinogenic properties (Carc. 1A) and acute toxicity. Avoid skin contact, inhalation, and ingestion. Regular health monitoring of exposed workers is essential.

Naphthalen-2-amine hydrochloride must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Storage areas should be secure with restricted access due to its carcinogenic properties. Keep containers properly labeled according to GHS requirements with appropriate hazard pictograms (GHS07, GHS08, GHS09) and maintain an inventory system for tracking.

Immediate action is required for any contact with naphthalen-2-amine hydrochloride. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with clean water for at least 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly for all exposure incidents due to the substance's carcinogenic and toxic properties.

Disposal of naphthalen-2-amine hydrochloride must comply with local and European waste regulations as hazardous chemical waste. The substance cannot be disposed of through regular waste streams due to its carcinogenic classification and environmental hazard properties. Contact licensed hazardous waste disposal companies for proper treatment and destruction. Maintain disposal records and certificates as required by regulatory authorities.

Transportation of naphthalen-2-amine hydrochloride must comply with ADR regulations for hazardous materials. Although specific ADR class information is not provided, the substance requires proper packaging, labeling, and documentation due to its hazardous properties. Transport must be performed by certified carriers with appropriate safety measures. Ensure proper emergency response information accompanies shipments and verify compliance with local transport regulations.

Naphthalen-2-amine hydrochloride is subject to extensive European regulations under REACH and CLP due to its carcinogenic classification (Carc. 1A). The substance requires safety data sheets, proper classification and labeling with danger signal word and specific pictograms. Usage may be restricted or require authorization depending on application. Employers must implement strict occupational health measures and comply with worker protection regulations.

Naphthalen-2-amine hydrochloride is available through OYSI, a specialized European distributor of technical chemicals. As a regulated carcinogenic substance, purchase requires proper documentation, end-use declarations, and compliance with applicable restrictions. OYSI provides technical support and regulatory guidance to ensure compliant procurement and handling. Contact OYSI directly for availability, specifications, and regulatory requirements for your specific application.