Naphthalen-1-ol

C10H8O

naphthalen-1-ol

CAS90-15-3
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
90-15-3
EC Number
201-969-4
UN Number
2811
Index Number
604-029-00-5
PubChem CID
7005

Physical-chemical properties

Molecular Formula
C10H8O
Molar Mass
144.17 g/mol
IUPAC Name
naphthalen-1-ol

Chemical Identifiers

InChI
InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H
InChI Key
KJCVRFUGPWSIIH-UHFFFAOYSA-N

Overview

Naphthalen-1-ol (CAS 90-15-3) is an aromatic organic compound with hydroxyl functionality and notable chemical reactivity properties. This organic compound, also known by its IUPAC name naphthalen-1-ol, represents a significant hydroxylated naphthalene derivative with the molecular formula C10H8O and a molecular weight of 144.17 g/mol. As a member of the naphthol family, this substance exhibits characteristic aromatic properties combined with phenolic reactivity due to its hydroxyl group attachment to the naphthalene ring system. The compound's structure provides unique chemical versatility that makes it valuable across multiple industrial applications. From a safety perspective, naphthalen-1-ol requires careful handling protocols due to its classification under several hazard categories. The substance carries acute toxicity classifications (Acute Tox. 4), skin irritation properties (Skin Irrit. 2), serious eye damage potential (Eye Dam. 1), and specific target organ toxicity (STOT SE 3). These characteristics necessitate appropriate personal protective equipment and handling procedures, with the compound classified under ADR Class 6.1 for transportation purposes. The associated GHS pictograms (GHS07, GHS05) and "Danger" signal word emphasize the importance of proper safety protocols during storage, handling, and processing. Industrial applications of naphthalen-1-ol span several sectors, primarily focusing on chemical synthesis intermediates, dye manufacturing, and pharmaceutical precursor applications. The compound serves as a crucial building block in organic synthesis reactions, particularly in the production of specialized aromatic compounds. Unlike simpler compounds such as 2-hexoxyethanol, naphthalen-1-ol's extended aromatic system provides enhanced stability and specific reactivity patterns valuable in complex synthetic pathways. OYSI maintains reliable supply capabilities for naphthalen-1-ol, ensuring consistent availability for European industrial customers requiring this specialized aromatic compound.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; STOT SE 3; Skin Irrit. 2; Eye Dam. 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H318

Causes serious eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2811
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping Name1-Naphthol
Marine PollutantNo

Frequently Asked Questions

What is naphthalen-1-ol?

Naphthalen-1-ol is an organic chemical compound with the molecular formula C10H8O and CAS number 90-15-3. It belongs to the class of naphthols, which are derivatives of naphthalene with a hydroxyl group attached. With a molecular weight of 144.17 g/mol, this aromatic compound is also known as 1-naphthol or α-naphthol and serves as an important intermediate in various chemical processes.

What are the physicochemical properties of naphthalen-1-ol?

Naphthalen-1-ol appears as white to pale yellow crystalline solid at room temperature with a characteristic phenolic odor. It has moderate solubility in water but dissolves readily in organic solvents like ethanol, ether, and acetone. The compound has a melting point around 95-96°C and exhibits typical aromatic properties due to its naphthalene backbone structure combined with the polar hydroxyl functional group.

What is naphthalen-1-ol used for?

Naphthalen-1-ol serves as a key intermediate in the production of dyes, particularly azo dyes and sulfonic acid derivatives. It is widely used in the synthesis of pharmaceuticals, rubber antioxidants, and photographic chemicals. The compound also finds application in the manufacturing of perfumes, fungicides, and as a coupling agent in analytical chemistry for colorimetric determinations and chromatographic procedures.

How to handle naphthalen-1-ol safely?

Naphthalen-1-ol requires careful handling due to its Acute Tox. 4, Skin Irrit. 2, Eye Dam. 1, and STOT SE 3 classifications. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation in work areas and avoid inhalation of dust or vapors. Handle in a well-ventilated area or fume hood to prevent exposure and potential health effects.

How to store naphthalen-1-ol correctly?

Naphthalen-1-ol should be stored in tightly closed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep containers sealed to prevent contamination and moisture absorption. Store separately from incompatible materials such as strong oxidizing agents and acids. Maintain storage temperatures below 25°C and ensure proper labeling with hazard information for safe identification.

What to do in case of contact with naphthalen-1-ol?

In case of skin contact with naphthalen-1-ol, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of clean water for at least 15 minutes and seek medical attention promptly due to the Eye Dam. 1 classification. If inhaled, move to fresh air immediately and seek medical advice if symptoms persist.

How to dispose of naphthalen-1-ol appropriately?

Naphthalen-1-ol waste must be disposed of in accordance with local, national, and international regulations as hazardous chemical waste. Do not discharge into drains, water bodies, or soil. Contact licensed waste disposal companies for proper treatment and disposal. Small quantities can be incinerated in approved facilities at high temperatures. Always consult current waste disposal regulations and safety data sheets before disposal.

How to transport naphthalen-1-ol?

Naphthalen-1-ol is classified under ADR as Class 6.1 (Toxic substances), Packing Group III, indicating moderate toxicity during transport. It must be packaged in appropriate containers meeting UN specifications and properly labeled with hazard markings. Transport vehicles must carry appropriate documentation and emergency information. Ensure packages are secured to prevent damage during transit and comply with dangerous goods transportation regulations.

Is naphthalen-1-ol subject to specific regulations?

Naphthalen-1-ol is subject to REACH regulation in Europe and must be registered for commercial use. It falls under CLP regulation with specific hazard classifications (Acute Tox. 4, Skin Irrit. 2, Eye Dam. 1, STOT SE 3) requiring appropriate labeling with GHS07 and GHS05 pictograms. However, it is not currently listed as a SVHC (Substance of Very High Concern) under REACH Annex XIV.

Where to buy naphthalen-1-ol in Europe?

Naphthalen-1-ol is available through OYSI, a trusted European distributor of technical chemicals. As a specialized chemical distributor, OYSI provides high-quality naphthalen-1-ol with proper documentation including safety data sheets and certificates of analysis. Professional customers can contact OYSI for technical specifications, availability, and regulatory compliance support throughout Europe for their industrial and research applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.