N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide

C10H11ClN4

CAS135410-20-7
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
135410-20-7
UN Number
2761
Index Number
608-032-00-2
PubChem CID
213021

Physical-chemical properties

Molecular Formula
C10H11ClN4
Molar Mass
222.67 g/mol
IUPAC Name
N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide

Chemical Identifiers

InChI
InChI=1S/C10H11ClN4/c1-8(14-7-12)15(2)6-9-3-4-10(11)13-5-9/h3-5H,6H2,1-2H3
InChI Key
WCXDHFDTOYPNIE-UHFFFAOYSA-N

Overview

N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide (CAS 135410-20-7) is a neonicotinoid insecticide compound with selective neurotoxic properties and high aquatic toxicity. This chlorinated pyridine derivative represents a significant advancement in modern pest control chemistry, featuring a molecular structure that combines a pyridyl ring system with an imidamide functional group. With its molecular formula C10H11ClN4 and molecular weight of 222.67 g/mol, this compound demonstrates the sophisticated molecular design characteristic of contemporary agricultural chemistry solutions. The substance exhibits considerable toxicological properties, classified under multiple hazard categories including reproductive toxicity (Category 2), acute toxicity (Category 3), and severe aquatic toxicity for both acute and chronic exposure scenarios. These classifications necessitate strict handling protocols and appropriate safety measures during industrial processing and application. The compound carries the danger signal word and requires GHS08, GHS06, and GHS09 pictograms, reflecting its potential health and environmental impacts. Transportation falls under ADR Class 6.1, indicating its classification as a toxic substance requiring specialized logistics management. Industrial applications primarily focus on agricultural pest control formulations, where its neonicotinoid properties provide effective insecticidal activity through nicotinic acetylcholine receptor modulation. The compound also finds use in specialized research applications and as an intermediate in the synthesis of related pest control agents. Unlike simpler aromatic amines such as N-methylaniline, this compound offers targeted biological activity with enhanced selectivity profiles. Professional users should implement comprehensive safety protocols given the substance's toxicological profile and environmental persistence characteristics. OYSI maintains reliable supply chains for this technical grade material, supporting European industrial customers with consistent quality standards.

Safety & Classification

Danger
Classification:

Repr. 2; Acute Tox. 3; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H301

Toxic if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2761
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameAcetamiprid (ISO)
Marine PollutantNo

Frequently Asked Questions

What is N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide?

N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide is a synthetic organic compound with the molecular formula C10H11ClN4 and CAS number 135410-20-7. This chemical substance has a molecular weight of 222.67 g/mol and belongs to the neonicotinoid class of compounds. It is characterized by its pyridine ring structure with chlorine substitution and cyano-methylethanimidamide functional groups, making it a specialized chemical intermediate with specific industrial applications.

What are the physicochemical properties of N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide?

N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide is a crystalline solid at room temperature with a molecular weight of 222.67 g/mol. The compound contains chlorine, nitrogen, and carbon atoms arranged in a pyridine-based structure. Its physicochemical properties include moderate polarity due to the presence of nitrogen-containing functional groups and the chlorinated pyridine ring. The substance requires careful handling due to its classification as hazardous material with reproductive and acute toxicity concerns.

What is N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide used for?

N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide is primarily used as a chemical intermediate in the synthesis of neonicotinoid compounds and related agricultural chemicals. The compound serves as a key building block in pharmaceutical and agrochemical research and development. Its specific molecular structure makes it valuable for creating derivatives with targeted biological activity. Industrial applications include use in specialized chemical synthesis processes where its unique pyridine-chlorine-cyano combination provides specific reactivity profiles.

How to handle N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide safely?

N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide requires strict safety protocols due to its Acute Tox. 3 and Repr. 2 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Pregnant women should avoid exposure due to reproductive toxicity concerns. Emergency washing facilities must be readily available, and personnel should be trained in proper handling procedures.

How to store N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide correctly?

N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Storage areas should be equipped with appropriate spill containment measures due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1). The substance should be kept away from incompatible materials and stored according to local chemical storage regulations. Access should be restricted to trained personnel only, with proper labeling and safety data sheets readily available.

What to do in case of contact with N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide?

In case of skin contact with N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air and seek medical attention if breathing difficulties occur. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet.

How to dispose of N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide appropriately?

N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide must be disposed of through licensed hazardous waste disposal facilities due to its toxic and environmentally hazardous properties. The substance cannot be disposed of in regular waste streams or sewerage systems due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Disposal must comply with local, national, and EU waste regulations. Empty containers should also be treated as hazardous waste. Professional waste management companies specializing in chemical disposal should handle the treatment and destruction process.

How to transport N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide?

N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide is classified as ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to international dangerous goods regulations. Transport vehicles must display appropriate hazard placards, and drivers require ADR certification. Shipping containers must meet UN specification requirements and include proper hazard labels and emergency response information. Transportation should only be conducted by certified carriers experienced in handling toxic chemicals.

Is N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide subject to particular regulations?

N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide is subject to multiple European regulations including REACH registration requirements and CLP classification obligations. The substance is not currently listed as SVHC (Substance of Very High Concern) but requires proper classification and labeling due to its hazardous properties. Companies handling this chemical must comply with occupational safety regulations, environmental protection laws, and chemical safety assessments. Import, manufacturing, and distribution activities must follow established regulatory frameworks for toxic and environmentally hazardous substances.

Where to buy N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide in Europe?

N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound with full regulatory compliance, including proper documentation, safety data sheets, and certificates of analysis. As a professional chemical distributor, OYSI ensures proper packaging, handling, and transportation according to ADR requirements. Contact OYSI directly for availability, specifications, and regulatory support for your specific application requirements in research, development, or industrial processes.

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N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide is a dangerous good. We support you with labeling, packaging, and transport documentation.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.