Methyl 2-hydroxypropanoate

C4H8O3

methyl 2-hydroxypropanoate

CAS547-64-8
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
547-64-8
EC Number
208-930-0
UN Number
3272
Index Number
607-092-00-7
PubChem CID
11040

Physical-chemical properties

Molecular Formula
C4H8O3
Molar Mass
104.10 g/mol
IUPAC Name
methyl 2-hydroxypropanoate

Chemical Identifiers

InChI
InChI=1S/C4H8O3/c1-3(5)4(6)7-2/h3,5H,1-2H3
InChI Key
LPEKGGXMPWTOCB-UHFFFAOYSA-N

Overview

Methyl 2-hydroxypropanoate (CAS 547-64-8) is an organic ester compound with hydroxyl functionality and flammable liquid properties. This versatile chemical intermediate, also known by its IUPAC designation methyl 2-hydroxypropanoate, represents an important class of hydroxy esters widely utilized across various industrial applications. With a molecular formula of C4H8O3 and molecular weight of 104.1 g/mol, this compound combines the reactive characteristics of both ester and alcohol functional groups, making it particularly valuable in synthetic chemistry and specialized manufacturing processes. The substance exhibits moderate flammability characteristics, classified as Flammable Liquid Category 3 under GHS regulations, requiring standard precautions for handling and storage of combustible organic solvents. Safety considerations include potential eye irritation and specific target organ toxicity, necessitating appropriate personal protective equipment and ventilation systems during industrial use. The compound falls under ADR Class 3 for transportation purposes, indicating its classification as a flammable liquid requiring proper shipping protocols. Key industrial applications include its use as a chemical intermediate in pharmaceutical synthesis, where its hydroxyl-ester structure provides selective reactivity for complex molecule construction. The compound also serves in specialty coating formulations and as a building block for biodegradable polymer synthesis. In comparison to related compounds such as pentyl formate, methyl 2-hydroxypropanoate offers enhanced functionality due to its secondary hydroxyl group, enabling additional derivatization possibilities. The European regulatory number EC 208-930-0 confirms its established status in commercial chemical markets. OYSI maintains reliable supply chains for this technical-grade chemical intermediate, supporting diverse industrial manufacturing requirements across Europe.

Safety & Classification

Warning
Classification:

Flam. Liq. 3; STOT SE 3; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H335

May cause respiratory irritation.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3272
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameMethyllactat
Marine PollutantNo

Frequently Asked Questions

What is methyl 2-hydroxypropanoate?

Methyl 2-hydroxypropanoate is an organic ester compound with the molecular formula C4H8O3 and CAS number 547-64-8. This chemical substance has a molecular weight of 104.1 g/mol and belongs to the class of hydroxycarboxylic acid esters. It is classified as a flammable liquid with potential eye irritation and specific target organ toxicity properties, requiring appropriate safety precautions during handling and storage.

What are the physicochemical properties of methyl 2-hydroxypropanoate?

Methyl 2-hydroxypropanoate is a liquid at room temperature with flammable characteristics classified under Flam. Liq. 3. The compound exhibits typical ester properties and contains both hydroxyl and ester functional groups. As an organic solvent-type substance, it demonstrates moderate volatility and requires proper ventilation during use. Its chemical structure makes it reactive under certain conditions, particularly regarding its flammability classification.

What is methyl 2-hydroxypropanoate used for?

Methyl 2-hydroxypropanoate serves as an important intermediate in organic synthesis and chemical manufacturing processes. It is commonly used in pharmaceutical and fine chemical industries for the production of various compounds. The substance acts as a building block in synthetic pathways and can function as a solvent in specific applications. Its ester functionality makes it valuable for esterification and transesterification reactions in industrial processes.

How to handle methyl 2-hydroxypropanoate safely?

Methyl 2-hydroxypropanoate requires careful handling due to its flammable nature and potential for eye irritation. Wear appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Ensure adequate ventilation to prevent vapor accumulation and avoid ignition sources. Handle in areas equipped with fire safety equipment and eyewash stations. Follow proper grounding procedures to prevent static electricity buildup during transfer operations.

How to store methyl 2-hydroxypropanoate correctly?

Methyl 2-hydroxypropanoate must be stored in a cool, dry, well-ventilated area away from heat sources and ignition points. Keep containers tightly closed and use fire-resistant storage cabinets when possible. Store away from incompatible materials such as strong oxidizing agents and bases. Maintain storage temperatures below flash point and ensure proper labeling with GHS02 and GHS07 pictograms. Regular inspection of containers for leaks or damage is essential.

What to do in case of contact with methyl 2-hydroxypropanoate?

In case of eye contact with methyl 2-hydroxypropanoate, immediately flush with plenty of clean water for at least 15 minutes and seek medical attention due to its eye irritant properties. For skin contact, wash thoroughly with soap and water. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Remove contaminated clothing and wash before reuse.

How to dispose of methyl 2-hydroxypropanoate properly?

Methyl 2-hydroxypropanoate waste must be disposed of according to local, national, and international regulations as hazardous waste. Contact authorized waste disposal companies specialized in flammable liquid disposal. Do not pour down drains or release into the environment. Small quantities may be incinerated in appropriate facilities with proper emission controls. Always consult local environmental authorities for specific disposal requirements and maintain proper waste documentation.

How to transport methyl 2-hydroxypropanoate?

Methyl 2-hydroxypropanoate is classified under ADR Class 3 (flammable liquids), Packing Group III for transportation purposes. Use appropriate UN-specification packaging and ensure proper labeling with hazard diamonds. Vehicles must comply with ADR regulations for Class 3 substances including proper ventilation and fire safety equipment. Drivers require ADR certification and transport documents must include proper shipping names and hazard information.

Is methyl 2-hydroxypropanoate subject to specific regulations?

Methyl 2-hydroxypropanoate is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification showing Warning signal word with GHS02 and GHS07 pictograms. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational safety regulations, proper labeling requirements, and safety data sheet provisions. Industrial users should verify specific regulatory requirements in their jurisdiction.

Where to buy methyl 2-hydroxypropanoate in Europe?

Methyl 2-hydroxypropanoate is available through OYSI, a specialized European distributor of technical chemicals and industrial raw materials. OYSI provides this substance with complete regulatory documentation, safety data sheets, and technical support. As an established European chemical distributor, OYSI ensures compliance with REACH regulations and provides reliable supply chains for industrial and research applications across European markets.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.