Methyl 2-hydroxybenzoate
C8H8O3
methyl 2-hydroxybenzoate
Consulting for Methyl 2-hydroxybenzoate
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Identification
- CAS Number
- 119-36-8
- EC Number
- 204-317-7
- UN Number
- Index Number
- 607-749-00-8
- PubChem CID
- 4133
Physical-chemical properties
- Molecular Formula
- C8H8O3
- Molar Mass
- 152.15 g/mol
- IUPAC Name
- methyl 2-hydroxybenzoate
Chemical Identifiers
- InChI
- InChI=1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3
- InChI Key
- OSWPMRLSEDHDFF-UHFFFAOYSA-N
Overview
Methyl 2-hydroxybenzoate (CAS 119-36-8) is an aromatic ester compound with analgesic and antimicrobial properties, commonly known as methyl salicylate. This versatile chemical compound, also referenced under EC number 204-317-7, belongs to the salicylate family and exhibits distinctive characteristics that make it valuable across multiple industrial applications. With a molecular formula of C8H8O3 and molecular weight of 152.15 g/mol, methyl 2-hydroxybenzoate presents as a colorless to pale yellow liquid with a characteristic wintergreen odor at room temperature. The compound requires careful handling due to its classification under several hazard categories. It carries reproductive toxicity warnings (Repr. 2), acute toxicity classification (Acute Tox. 4), and skin sensitization properties (Skin Sens. 1B), along with aquatic chronic toxicity concerns (Aquatic Chronic 3). These classifications necessitate appropriate safety protocols including proper ventilation, personal protective equipment, and adherence to GHS08 and GHS07 pictogram guidelines with the associated Warning signal word. Industrial applications primarily center on pharmaceutical intermediates, where methyl 2-hydroxybenzoate serves as a precursor in analgesic formulations and topical preparations. The fragrance and flavor industry utilizes this compound for its distinctive wintergreen scent profile, while the cosmetic sector incorporates it into various personal care formulations. Unlike compounds such as 4-nitrophenol which serves different industrial purposes, methyl 2-hydroxybenzoate's ester functionality provides unique solubility and stability characteristics essential for specific applications. OYSI maintains reliable supplies of methyl 2-hydroxybenzoate to support European industrial requirements, ensuring consistent quality standards for our technical chemical distribution network.
Safety & Classification
Repr. 2; Acute Tox. 4; Skin Sens. 1B; Aquatic Chronic 3
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Frequently Asked Questions
What is methyl 2-hydroxybenzoate?
Methyl 2-hydroxybenzoate is an organic chemical compound with the molecular formula C8H8O3 and CAS number 119-36-8. Also known as methyl salicylate or oil of wintergreen, it belongs to the ester family and has a molecular weight of 152.15 g/mol. This compound is classified as a reproductive toxicant category 2, acute toxin category 4, and skin sensitizer category 1B under CLP regulation, requiring careful handling in industrial applications.
What are the physicochemical properties of methyl 2-hydroxybenzoate?
Methyl 2-hydroxybenzoate is typically a colorless to pale yellow liquid at room temperature with a characteristic sweet, minty odor reminiscent of wintergreen. It has good solubility in alcohol and oils but limited solubility in water. The compound has a boiling point around 222°C and a density of approximately 1.17 g/cm³. Its ester structure makes it relatively stable under normal conditions but sensitive to hydrolysis in alkaline environments.
What is methyl 2-hydroxybenzoate used for?
Methyl 2-hydroxybenzoate is primarily used in the fragrance and flavor industry as a wintergreen flavoring agent in food products, cosmetics, and pharmaceuticals. It serves as an intermediate in organic synthesis for producing other salicylate derivatives. The compound is also utilized in topical analgesic preparations due to its anti-inflammatory properties and finds applications in the manufacture of UV filters and preservatives for various industrial formulations.
How to handle methyl 2-hydroxybenzoate safely?
Methyl 2-hydroxybenzoate requires careful handling due to its reproductive toxicity and skin sensitization potential. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation in work areas and avoid direct skin contact or inhalation of vapors. Use the substance only in controlled industrial environments with proper training, as it poses acute toxicity risks and may cause allergic skin reactions upon exposure.
How to store methyl 2-hydroxybenzoate correctly?
Methyl 2-hydroxybenzoate should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers upright and protected from physical damage. Store separately from strong oxidizers, acids, and bases to prevent incompatible reactions. Maintain storage temperatures below 25°C when possible and ensure proper labeling with hazard information. Implement appropriate spill containment measures and restrict access to authorized personnel only.
What to do in case of contact with methyl 2-hydroxybenzoate?
Methyl 2-hydroxybenzoate exposure requires immediate action due to its toxicity profile. For skin contact, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, rinse with clean water for 15 minutes and seek medical attention. In case of inhalation, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical care. Always consult a physician after any significant exposure.
How to dispose of methyl 2-hydroxybenzoate appropriately?
Methyl 2-hydroxybenzoate disposal must comply with local and European waste regulations due to its hazardous classification. The substance should be treated as hazardous chemical waste and disposed of through licensed waste management facilities. Never discharge into sewers, waterways, or soil as it may cause environmental harm (Aquatic Chronic 3). Small quantities may be incinerated at appropriate high-temperature facilities. Always consult local authorities and waste disposal experts for specific disposal requirements in your region.
How to transport methyl 2-hydroxybenzoate?
Methyl 2-hydroxybenzoate transport should follow general chemical shipping guidelines as no specific ADR classification is assigned to this substance. Use appropriate packaging that prevents leakage and damage during transit. Ensure proper labeling with hazard pictograms (GHS07, GHS08) and safety information. Transport vehicles should be equipped with emergency response equipment and drivers properly trained in chemical handling. Follow national and international regulations for chemical transport and maintain proper documentation throughout the shipping process.
Is methyl 2-hydroxybenzoate subject to specific regulations?
Methyl 2-hydroxybenzoate is subject to REACH regulation requiring registration for commercial use in the European Union. Under CLP regulation, it must be classified and labeled with Warning signal word and appropriate GHS pictograms (GHS07, GHS08). The substance is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational exposure limits, reproductive toxicity restrictions, and environmental protection measures. Always check current regulatory status as requirements may change.
Where to buy methyl 2-hydroxybenzoate in Europe?
Methyl 2-hydroxybenzoate is available through OYSI, a trusted European distributor of industrial chemicals. OYSI provides high-quality chemical products with proper documentation, safety data sheets, and regulatory compliance support across European markets. As a specialized chemical distributor, OYSI ensures reliable supply chains and technical support for industrial customers. Contact OYSI directly for pricing, availability, packaging options, and delivery throughout Europe while ensuring all regulatory requirements are met for your specific application.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.