Furan-2-carbaldehyde

C5H4O2

furan-2-carbaldehyde

CAS98-01-1
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
98-01-1
EC Number
202-627-7
UN Number
1199
Index Number
605-010-00-4
PubChem CID
7362

Physical-chemical properties

Molecular Formula
C5H4O2
Molar Mass
96.08 g/mol
IUPAC Name
furan-2-carbaldehyde

Chemical Identifiers

InChI
InChI=1S/C5H4O2/c6-4-5-2-1-3-7-5/h1-4H
InChI Key
HYBBIBNJHNGZAN-UHFFFAOYSA-N

Overview

Furan-2-carbaldehyde (CAS 98-01-1) is an aromatic aldehyde compound with a characteristic almond-like odor and significant reactivity in organic synthesis. This heterocyclic aldehyde, also known by its IUPAC name furan-2-carbaldehyde, represents an important building block in fine chemical manufacturing and pharmaceutical intermediate production. With the molecular formula C5H4O2 and a molecular weight of 96.08 g/mol, this compound features a furan ring system with an aldehyde functional group, making it highly versatile for various chemical transformations. The substance appears as a colorless to pale yellow liquid that darkens upon exposure to light and air due to oxidation processes. From a safety perspective, furan-2-carbaldehyde requires careful handling as it carries significant hazard classifications including carcinogenicity category 2 and acute toxicity. The compound displays GHS08 and GHS06 pictograms with a "Danger" signal word, reflecting its potential health risks. It can cause skin and eye irritation and is classified under ADR transport class 6.1 as a toxic substance. Proper ventilation, personal protective equipment, and adherence to safety protocols are essential when working with this material. The compound finds primary applications in pharmaceutical synthesis as an intermediate for drug development, particularly in the production of furan-containing bioactive molecules. It serves as a key starting material in fine chemical manufacturing for specialty compounds and is utilized in flavor and fragrance synthesis due to its distinctive aromatic properties. Unlike simpler aromatic compounds such as N-methylaniline, furan-2-carbaldehyde offers unique reactivity patterns due to its heterocyclic structure. OYSI maintains reliable supply chains for furan-2-carbaldehyde to support European industrial customers' technical requirements.

Safety & Classification

Danger
Classification:

Carc. 2; Acute Tox. 3 *; Acute Tox. 4 *; Acute Tox. 3 *; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H331

Toxic if inhaled.

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1199
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name2-Furaldehyd
Marine PollutantNo

Frequently Asked Questions

What is furan-2-carbaldehyde?

Furan-2-carbaldehyde is an organic compound with the molecular formula C5H4O2 and CAS number 98-01-1. It belongs to the furan family, featuring a five-membered aromatic ring containing oxygen with an aldehyde functional group attached. This compound has a molecular weight of 96.08 g/mol and is classified as a hazardous substance with carcinogenic properties (Category 2) and acute toxicity. It requires careful handling due to its multiple health hazards including skin and eye irritation.

What are the physicochemical properties of furan-2-carbaldehyde?

Furan-2-carbaldehyde is typically a colorless to light yellow liquid at room temperature with a characteristic almond-like odor. It has a molecular formula of C5H4O2 and a molar mass of 96.08 g/mol. The compound is soluble in organic solvents and has limited solubility in water. It is volatile and can readily evaporate at ambient temperatures, making proper ventilation essential during handling.

What is furan-2-carbaldehyde used for?

Furan-2-carbaldehyde serves as an important intermediate in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of various chemicals, including pharmaceuticals, agrochemicals, and fine chemicals. The compound also finds applications in flavor and fragrance industries due to its aromatic properties. Additionally, it serves as a building block for synthesizing more complex organic molecules in research and industrial processes.

How to handle furan-2-carbaldehyde safely?

Furan-2-carbaldehyde requires strict safety measures including wearing appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact completely. Use grounding equipment to prevent static discharge and ensure no ignition sources are present during handling due to its potential flammability.

How to store furan-2-carbaldehyde correctly?

Furan-2-carbaldehyde should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly sealed to prevent evaporation and contamination. Store away from incompatible materials such as strong oxidizing agents, acids, and bases. Temperature should be controlled to prevent decomposition, and storage areas should be equipped with appropriate spill containment measures and fire suppression systems.

What to do in case of contact with furan-2-carbaldehyde?

Immediate action is required upon contact with furan-2-carbaldehyde. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult emergency services if serious exposure occurs.

How to dispose of furan-2-carbaldehyde properly?

Furan-2-carbaldehyde disposal must comply with local and national hazardous waste regulations due to its classification as dangerous goods. The substance should never be poured down drains or disposed of with regular waste. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may be suitable for incineration at authorized facilities equipped to handle toxic compounds. Always check local environmental regulations before disposal.

How to transport furan-2-carbaldehyde?

Furan-2-carbaldehyde is classified under ADR as Class 6.1 (toxic substances), Packing Group II, requiring specific transport regulations. Packages must be properly labeled with appropriate hazard symbols (GHS06, GHS08) and marked with UN identification numbers. Vehicles must carry appropriate emergency equipment and drivers need hazardous materials training. Transport documents must include proper shipping names and emergency contact information according to dangerous goods regulations.

Is furan-2-carbaldehyde subject to specific regulations?

Furan-2-carbaldehyde is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification obligations. It is classified as Category 2 carcinogen requiring special handling and labeling. While not currently listed as a Substance of Very High Concern (SVHC), its hazardous properties mean it falls under various occupational health and safety regulations. Companies must maintain safety data sheets and comply with worker protection standards.

Where to buy furan-2-carbaldehyde in Europe?

Furan-2-carbaldehyde is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides high-quality chemical products with proper documentation including safety data sheets and certificates of analysis. As a professional chemical supplier, OYSI ensures compliance with European regulations and offers technical support for safe handling and applications. Contact OYSI directly for availability, specifications, and pricing information for furan-2-carbaldehyde.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.