Ethyl 4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-1-carboxylate

Ethyl 4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-1-carboxylate is an antifungal agent with CAS number 67914-69-6. This complex organic compound has a molecular formula of C27H30Cl2N4O5 and a molecular weight of 561.5 g/mol. It contains dichlorophenyl, imidazole, dioxolane, and piperazine structural components, making it effective against fungal infections through specific enzymatic inhibition mechanisms.

Ethyl 4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-1-carboxylate is a solid compound at room temperature with moderate lipophilicity due to its aromatic rings and ethyl ester group. The presence of imidazole and piperazine rings provides basic properties, while the dichlorophenyl substituent influences its solubility profile. The compound's complex structure affects its stability and bioavailability characteristics.

Ethyl 4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-1-carboxylate is primarily used as an antifungal pharmaceutical intermediate and research compound. It serves in the development of antifungal medications and therapeutic research applications. The compound is utilized in pharmaceutical manufacturing, laboratory research, and drug formulation studies where precise antifungal activity is required for specific therapeutic targets.

Safe handling requires appropriate personal protective equipment including gloves, safety goggles, and laboratory coats due to its Acute Tox. 4 and STOT RE 2 classifications. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and implement proper hygiene measures including hand washing after handling. Use appropriate engineering controls and follow established laboratory safety protocols to minimize exposure risks.

Store in tightly sealed containers in a cool, dry place away from direct sunlight and heat sources. Keep containers properly labeled and maintain controlled temperature conditions to preserve chemical stability. Ensure adequate ventilation in storage areas and separate from incompatible materials. Implement proper inventory management and access control measures, especially considering its hazard classifications. Regular inspection of container integrity is recommended to prevent environmental release.

Immediate first aid measures include removing contaminated clothing and flushing affected skin or eyes with plenty of water for at least 15 minutes. If inhaled, move the person to fresh air immediately and monitor breathing. In case of ingestion, do not induce vomiting and seek immediate medical attention. Contact emergency services if severe symptoms develop and provide the safety data sheet to medical personnel for proper treatment guidance.

Disposal must comply with local, national, and international waste regulations due to its environmental hazard classifications (Aquatic Acute 1, Aquatic Chronic 1). Contact authorized waste disposal companies specializing in pharmaceutical and chemical waste treatment. Prevent release to waterways, sewers, or soil. Incineration at approved high-temperature facilities may be required. Maintain proper documentation of disposal procedures and quantities for regulatory compliance and environmental protection.

Transport follows ADR Class 9 regulations as a miscellaneous dangerous substance with Packing Group III classification. Use appropriate UN-specification packaging with proper labeling and documentation. Ensure compliance with dangerous goods transportation requirements including driver certification and vehicle placarding. Implement proper loading, securing, and segregation procedures during transport. Emergency response information must accompany shipments for incident management.

The compound is subject to CLP regulation for classification, labeling, and packaging requirements due to its hazard classifications. REACH registration obligations may apply depending on import/manufacture quantities and uses. While not currently listed as an SVHC substance, its pharmaceutical nature may trigger additional regulatory oversight. Compliance with pharmaceutical regulations and environmental protection laws is mandatory, particularly regarding aquatic environmental protection due to its environmental hazard profile.

OYSI serves as a reliable European distributor for ethyl 4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-1-carboxylate, providing quality chemical products to pharmaceutical and research industries. As an established chemical distributor, OYSI ensures proper handling, documentation, and regulatory compliance throughout the supply chain. Contact OYSI directly for product availability, specifications, and technical support to meet your specific pharmaceutical research or manufacturing requirements.