(E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal

(E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal is an organic compound with the molecular formula C20H18FNO and a molecular weight of 307.4 g/mol. This fluorinated indole derivative contains an aldehyde functional group and features a complex aromatic structure with a fluorophenyl substituent. The compound is classified under CAS number 93957-50-7 and is primarily used in specialized chemical applications requiring its unique structural properties.

(E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal is a solid organic compound at room temperature with a molecular weight of 307.4 g/mol. The compound contains fluorine, which typically influences its polarity and solubility characteristics. As an aldehyde-containing molecule with aromatic rings, it likely exhibits limited water solubility but good solubility in organic solvents. The presence of the fluorophenyl group and indole structure contributes to its stability and specific reactivity profile.

(E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal is primarily used as an intermediate in pharmaceutical synthesis and fine chemical manufacturing. The compound's unique indole structure with fluorophenyl substitution makes it valuable for developing bioactive molecules and pharmaceutical compounds. Its aldehyde functionality allows for further chemical modifications, making it useful in organic synthesis applications where specific structural features are required for target molecule construction.

(E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal requires careful handling due to its skin sensitizing properties (Skin Sens. 1). Wear appropriate personal protective equipment including nitrile gloves, safety goggles, and protective clothing to prevent skin contact. Work in well-ventilated areas or under fume hoods to avoid inhalation. Avoid direct contact with skin and eyes, and wash hands thoroughly after handling. The compound carries a Warning signal word indicating moderate hazard potential requiring standard laboratory safety precautions.

(E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal should be stored in a cool, dry place away from direct sunlight and heat sources. Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong oxidizers and bases. Due to its aquatic toxicity classification, ensure proper containment to prevent environmental release. Maintain storage temperature according to manufacturer specifications and ensure adequate ventilation in storage areas to prevent vapor accumulation.

Immediate action is required if contact occurs with (E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal due to its skin sensitizing properties. For skin contact, immediately wash the affected area with plenty of soap and water for at least 15 minutes. Remove contaminated clothing. If eye contact occurs, flush with clean water for 15 minutes and seek medical attention. In case of inhalation, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention.

(E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal must be disposed of as hazardous waste due to its aquatic toxicity classification (Aquatic Acute 1; Aquatic Chronic 1). Contact authorized hazardous waste disposal companies for proper treatment and disposal. Do not discharge to sewers, waterways, or soil as this can cause significant environmental harm. Collect waste in appropriate containers and label clearly. Follow local and national regulations for hazardous chemical waste disposal and maintain proper documentation for waste tracking.

(E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation. This classification indicates it presents a relatively low transport hazard but still requires proper packaging and documentation. Use UN-approved packaging suitable for Class 9 materials and ensure proper labeling with appropriate hazard markings. Transport documents must include correct shipping names and hazard classifications. Follow ADR regulations for loading, segregation, and vehicle requirements during transport.

(E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal is subject to EU CLP regulation with GHS07 and GHS09 pictograms and Warning signal word. The compound is not currently listed as a Substance of Very High Concern (SVHC) under REACH regulation. However, it must comply with standard chemical registration requirements and safety data sheet provisions. Users must follow occupational exposure limits and environmental protection measures due to its skin sensitizing and aquatic toxicity properties. National regulations may impose additional handling and use restrictions.

(E)-3-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]prop-2-enal is available through OYSI, a specialized European distributor of fine chemicals and pharmaceutical intermediates. OYSI provides this compound with full regulatory compliance including safety data sheets and proper packaging for safe transport. As a specialized chemical, it may require custom ordering with specific purity grades and quantities. Contact OYSI directly for availability, technical specifications, and delivery options across European markets while ensuring compliance with local regulatory requirements.