Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate is an organophosphorus compound with the molecular formula C10H16N3O5PS2 and CAS number 162208-27-7. This chemical substance has a molecular weight of 353.4 g/mol and contains thiazole and phosphinate functional groups. It is classified as hazardous with multiple safety concerns including acute toxicity, skin sensitization, and environmental hazards to aquatic life.

The compound has a molecular formula C10H16N3O5PS2 with a molecular weight of 353.4 g/mol. As an organophosphorus compound containing sulfur and nitrogen heteroatoms, it likely exists as a solid at room temperature. The presence of polar functional groups including phosphinate, thiazole, and oxime moieties suggests moderate to good solubility in polar solvents. Specific physical properties such as melting point, color, and odor would require experimental determination.

This compound is primarily used as an intermediate in pharmaceutical and agrochemical synthesis due to its thiazole and organophosphorus structure. The presence of amino-thiazole moieties makes it valuable in the development of bioactive molecules, particularly for antimicrobial or enzyme inhibition applications. It may also serve as a building block in organic synthesis for creating more complex molecular structures in research and development laboratories.

Safe handling requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Acute Tox. 4 and Skin Sens. 1 classifications. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure proper hygiene practices including thorough handwashing after handling. Emergency eyewash stations and safety showers should be readily accessible.

The compound should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and direct sunlight. Given its organophosphorus nature, keep away from strong oxidizing agents and bases. Storage areas should be equipped with appropriate containment measures and restricted access due to its toxicity classification. Ensure containers are properly labeled and inventory is regularly monitored for degradation or leakage.

In case of skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet and contact poison control or emergency services when necessary.

Disposal must comply with local and national hazardous waste regulations due to its toxic and environmental hazard classifications. The compound should be collected in appropriate hazardous waste containers and disposed of through licensed waste management facilities. Never dispose of it in regular trash, sewers, or environmental drains due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Consult local environmental authorities for specific disposal requirements and approved disposal methods.

Transportation is regulated under ADR Class 6.1 (Toxic substances) Packing Group III, indicating moderate toxicity requiring specific packaging and labeling requirements. Packages must bear appropriate hazard labels and shipping documentation must include proper shipping names and emergency response information. Only authorized carriers trained in hazardous materials transport should handle shipments. Ensure compliance with international transport regulations including IATA for air transport and IMDG for sea transport.

The compound is subject to EU CLP Regulation requiring appropriate classification, labeling, and safety data sheets due to its hazardous properties. It falls under REACH Regulation requiring registration for manufacture or import above tonnage thresholds. While not currently listed as a SVHC (Substance of Very High Concern), its toxic and environmental properties may subject it to future regulatory scrutiny. Users must comply with workplace safety regulations and environmental protection laws.

OYSI serves as a reliable European distributor for this specialized chemical compound, offering professional-grade materials to research institutions and industrial customers. As an established chemical distributor, OYSI ensures proper handling, documentation, and regulatory compliance for hazardous substances. Contact OYSI directly for availability, technical specifications, and pricing information. Alternative suppliers may include specialized fine chemical manufacturers, though verification of quality and regulatory compliance is essential.