Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate

C10H16N3O5PS2

diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate

CAS162208-27-7
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
162208-27-7
EC Number
426-790-0
UN Number
2811
Index Number
607-572-00-6
PubChem CID
45357829

Physical-chemical properties

Molecular Formula
C10H16N3O5PS2
Molar Mass
353.40 g/mol
IUPAC Name
diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate

Chemical Identifiers

InChI
InChI=1S/C10H16N3O5PS2/c1-4-16-19(20,17-5-2)18-9(14)8(13-15-3)7-6-21-10(11)12-7/h6H,4-5H2,1-3H3,(H2,11,12)/b13-8-
InChI Key
JNSGIVNNHKGGRU-JYRVWZFOSA-N

Overview

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate (CAS 162208-27-7) is an organophosphorus compound with thiazole functionality and oxime structure featuring antimicrobial properties. This specialized chemical compound represents a sophisticated example of organophosphorus chemistry, incorporating multiple functional groups including thiazole rings, oxime moieties, and phosphinate ester structures. With a molecular formula of C10H16N3O5PS2 and molecular weight of 353.4 g/mol, this substance demonstrates the complexity achievable in modern synthetic chemistry. The presence of the 2-amino-1,3-thiazol-4-yl group contributes to its biological activity profile, while the methoxyimino acetate portion enhances its chemical stability and bioavailability characteristics. The compound exhibits significant safety considerations, classified under multiple hazard categories including acute toxicity (oral and dermal routes), skin sensitization potential, and specific target organ toxicity following repeated exposure. Environmental considerations are equally important, as it demonstrates both acute and chronic aquatic toxicity, requiring careful handling and disposal protocols. The ADR classification of 6.1 indicates its status as a toxic substance for transportation purposes, necessitating specialized logistics procedures. Industrial applications typically focus on antimicrobial and preservative functions, particularly in specialized formulations requiring both efficacy and chemical stability. The compound finds use in agricultural chemical formulations and specialty chemical manufacturing processes. Unlike simpler compounds such as 4-aminophenol, this molecule's complex structure enables highly specific biological interactions. OYSI maintains availability of this technical-grade chemical compound for qualified industrial customers throughout Europe, supported by comprehensive documentation and regulatory compliance materials.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; STOT RE 2 *; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2811
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameDiethylthiophosphoryl-cis-(2-aminothiazol-4-yl)methoxyiminoacetat
Marine PollutantNo

Frequently Asked Questions

What is diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate?

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate is an organophosphorus compound with the molecular formula C10H16N3O5PS2 and CAS number 162208-27-7. This chemical has a molecular weight of 353.4 g/mol and features a complex structure containing thiazole, phosphorus, and oxime functional groups. It is classified as a moderately hazardous substance requiring careful handling due to its toxicological properties and environmental impact potential.

What are the physicochemical properties of diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate?

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate is a complex organic molecule with a molecular weight of 353.4 g/mol. The compound contains multiple functional groups including phosphorus, sulfur, and nitrogen atoms, which influence its chemical behavior. Specific physical properties such as melting point, boiling point, and solubility characteristics depend on the exact formulation and purity grade. The presence of polar groups suggests potential solubility in polar solvents.

What is diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate used for?

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate is primarily used as an intermediate in pharmaceutical and agrochemical synthesis. Its complex structure containing thiazole and phosphorus moieties makes it valuable for developing bioactive compounds. The compound serves as a building block in research and development applications, particularly in the synthesis of specialized pharmaceuticals or crop protection agents. Industrial applications focus on its role as a chemical intermediate rather than as an end-use product.

How to handle diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate safely?

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume extraction due to its acute toxicity classification (Acute Tox. 4). The substance is a skin sensitizer, requiring avoiding direct contact. Use proper engineering controls and follow good laboratory practices to minimize exposure risks during handling and processing operations.

How to store diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate correctly?

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly closed and properly labeled according to GHS requirements. Due to its organophosphorus nature, avoid storage near strong oxidizers or bases. Maintain appropriate temperature conditions and ensure adequate containment to prevent environmental release. Storage areas should be equipped with appropriate spill control measures and emergency equipment.

What to do in case of contact with diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate?

Immediate medical attention is recommended following contact with diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate due to its acute toxicity classification. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, rinse immediately with clean water for at least 15 minutes. If inhaled, move to fresh air and seek medical attention. For ingestion, do not induce vomiting and contact emergency services immediately.

How to dispose of diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate appropriately?

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate must be disposed of through licensed hazardous waste facilities due to its toxic and environmentally hazardous properties. The substance is classified as aquatic acute and chronic hazard, requiring specialized treatment to prevent environmental contamination. Disposal must comply with local and EU waste regulations including the European Waste Catalogue. Contact certified waste management companies experienced in handling organophosphorus compounds for proper disposal procedures.

How to transport diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate?

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation for road transport within Europe. Vehicles must carry appropriate emergency equipment and drivers need hazardous goods training certification. Shipping containers must meet UN specification requirements and display proper hazard labels including GHS07, GHS08, and GHS09 pictograms to ensure safe transport and handling.

Is diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate subject to specific regulations?

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate is regulated under European REACH and CLP regulations due to its hazardous classification. The substance requires proper registration, classification, and safety data sheet provision. It is not currently listed as a Substance of Very High Concern (SVHC). Companies handling this chemical must comply with occupational health regulations and environmental protection requirements. Users must implement appropriate risk management measures and maintain compliance with chemical safety legislation.

Where to buy diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate in Europe?

Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to qualified industrial customers, research institutions, and pharmaceutical companies with appropriate handling capabilities. Due to the substance's hazardous classification, purchases require proper documentation and compliance verification. Contact OYSI's technical team for availability, specifications, and regulatory documentation including safety data sheets and certificates of analysis for your specific application requirements.

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Diethoxyphosphinothioyl (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate is a dangerous good. We support you with labeling, packaging, and transport documentation.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.