Chromen-2-one

Chromen-2-one is an organic heterocyclic compound with the molecular formula C9H6O2 and CAS number 91-64-5. It belongs to the coumarin family, featuring a benzopyrone structure consisting of a benzene ring fused to a pyrone ring. With a molecular weight of 146.14 g/mol, this compound serves as an important intermediate in organic synthesis and pharmaceutical applications.

Chromen-2-one is typically a white to pale yellow crystalline solid at room temperature with a characteristic sweet, vanilla-like odor. It has a melting point around 68-70°C and is moderately soluble in organic solvents like ethanol and acetone, while showing limited solubility in water. The compound exhibits aromatic properties due to its conjugated ring system and can undergo various chemical reactions typical of lactones.

Chromen-2-one is primarily used as an intermediate in pharmaceutical synthesis, particularly in the production of anticoagulant medications and other therapeutic compounds. It serves as a building block in organic synthesis for creating various coumarin derivatives. Additionally, it finds applications in the fragrance industry due to its pleasant odor, and in research laboratories for developing new chemical compounds with potential biological activities.

Chromen-2-one should be handled with standard laboratory safety practices including wearing appropriate personal protective equipment such as safety glasses, gloves, and lab coats. Work should be conducted in well-ventilated areas or under a fume hood to avoid inhalation of dust or vapors. Avoid direct skin and eye contact, and ensure proper hygiene by washing hands thoroughly after handling. Keep away from heat sources and open flames.

Chromen-2-one should be stored in a cool, dry place away from direct sunlight and heat sources in tightly sealed containers. The storage area should be well-ventilated and maintained at room temperature or below. Keep the compound away from strong oxidizing agents and incompatible materials. Use appropriate labeling and ensure containers are properly sealed to prevent moisture absorption and contamination. Follow local storage regulations for chemical substances.

In case of skin contact with chromen-2-one, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, flush eyes thoroughly with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately. In case of ingestion, do not induce vomiting and seek medical attention. Always consult a physician if symptoms develop or persist after exposure.

Chromen-2-one should be disposed of in accordance with local, national, and international waste regulations. Do not pour the substance down drains or into the environment. Small quantities can typically be disposed of through licensed chemical waste disposal services. Contaminated materials and packaging should also be treated as chemical waste. Consult your local environmental authorities or waste management specialists for specific disposal requirements in your region.

Chromen-2-one can be transported following standard chemical shipping procedures as it does not appear to have specific ADR transport classification requirements. Use appropriate packaging that prevents spillage and breakage during transit. Ensure packages are properly labeled with substance identification and any relevant safety information. Follow carrier-specific requirements and general chemical transport regulations. Always verify current transport regulations with your shipping provider before dispatch.

Chromen-2-one is subject to standard chemical regulations including REACH registration requirements in the European Union for commercial use. It is not classified as a Substance of Very High Concern (SVHC) and does not appear to have specific CLP hazard classifications. However, users must comply with general chemical safety regulations, workplace safety standards, and any applicable local or national chemical control legislation in their jurisdiction.

Chromen-2-one is available through OYSI, a European distributor of technical chemicals serving various industries across the continent. OYSI provides reliable supply chains and technical support for chemical products to professional users. Contact OYSI directly to inquire about availability, specifications, packaging options, and delivery arrangements for chromen-2-one. Always verify that the supplier meets your quality and regulatory requirements before purchasing.