Chloromethane

CH3Cl

chloromethane

CAS74-87-3
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS04 Gefahrensymbol: Unter Druck stehende Gase – Gasflasche
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
Danger

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Identification

CAS Number
74-87-3
EC Number
200-817-4
UN Number
1063
Index Number
602-001-00-7
PubChem CID
6327

Physical-chemical properties

Molecular Formula
CH3Cl
Molar Mass
50.49 g/mol
IUPAC Name
chloromethane

Chemical Identifiers

InChI
InChI=1S/CH3Cl/c1-2/h1H3
InChI Key
NEHMKBQYUWJMIP-UHFFFAOYSA-N

Overview

Chloromethane (CAS 74-87-3) is a halogenated hydrocarbon gas with high flammability and significant industrial applications as a methylating agent and refrigerant precursor. This single-carbon chlorinated compound, with the molecular formula CH3Cl and molecular weight of 50.49 g/mol, represents one of the simplest organochlorine chemicals in industrial use. Also known by its IUPAC name chloromethane, this colorless gas exhibits typical characteristics of light alkyl halides, sharing certain reactive properties with other industrial gases like bromoethene in halogenation processes. The substance presents multiple hazard classifications requiring careful handling protocols. As a Category 1 flammable gas, chloromethane poses significant fire and explosion risks, particularly in confined spaces where vapor accumulation can occur. Its classification as a Category 2 carcinogen and Category 2 specific target organ toxin following repeated exposure necessitates stringent workplace safety measures and proper ventilation systems during industrial operations. Key physical properties include its gaseous state at ambient conditions and high volatility, making containment and transfer procedures critical safety considerations. The compound's reactivity profile makes it valuable for methylation reactions in pharmaceutical and chemical synthesis, where it serves as an effective methyl donor. Industrial applications primarily include its use as an intermediate in silicone polymer production and as a precursor for manufacturing higher-value methylating agents used in pharmaceutical synthesis. In refrigeration applications, chloromethane historically served as a cooling medium, though environmental regulations have largely restricted this usage. The chemical industry continues to utilize chloromethane in specialized synthetic pathways where its selective reactivity provides advantages over alternative methylating compounds. OYSI maintains reliable supply chains for chloromethane to support European industrial operations requiring this specialized halogenated compound.

Safety & Classification

Danger
Classification:

Flam. Gas 1; Press. Gas; Carc. 2; STOT RE 2 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H220

Extremely flammable gas.

H351

Suspected of causing cancer.

H373

May cause damage to organs through prolonged or repeated exposure.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number1063
ADR Class2
Packing Group
Tunnel CodeB/D
Proper Shipping NameMethylchlorid, unter Druck verflüssigt
Marine PollutantNo

Frequently Asked Questions

What is chloromethane?

Chloromethane is an organohalogen compound with the chemical formula CH3Cl and molecular weight of 50.49 g/mol. It belongs to the family of methyl halides and serves as an important industrial chemical intermediate. This compound is classified as a flammable gas under pressure with potential carcinogenic properties (Category 2) and can cause damage to organs through repeated exposure. It appears as a colorless gas at room temperature and is widely used in chemical manufacturing processes.

What are the physicochemical properties of chloromethane?

Chloromethane is a colorless gas at room temperature and atmospheric pressure with a faintly sweet, ethereal odor. It has a boiling point of -24.2°C and is moderately soluble in water. The compound is highly flammable and exists as a pressurized gas in commercial applications. It has a density lower than water and can form explosive mixtures with air. Chloromethane is miscible with most organic solvents and readily liquefies under moderate pressure.

What is chloromethane used for?

Chloromethane serves primarily as a chemical intermediate in the production of silicones, methyl cellulose, and quaternary ammonium compounds. It is extensively used in the manufacture of agricultural chemicals, pharmaceuticals, and various industrial chemicals. The compound also finds application in foam blowing processes and as a methylating agent in chemical synthesis. Additionally, it serves as a solvent in specialized industrial processes and as a refrigerant in certain applications, though this use has been largely phased out.

How to handle chloromethane safely?

Chloromethane requires strict safety protocols including use of appropriate respiratory protection, gas-tight clothing, and safety goggles. Work should be conducted in well-ventilated areas or under fume hoods to prevent accumulation of vapors. Eliminate all ignition sources as the compound is highly flammable. Use explosion-proof electrical equipment and avoid static electricity buildup. Regular monitoring of exposure levels is essential due to its potential carcinogenic properties and organ toxicity. Emergency shower and eyewash facilities should be readily accessible.

How to store chloromethane correctly?

Chloromethane must be stored in properly designed pressure vessels in cool, dry, well-ventilated areas away from heat sources and ignition points. Storage areas should be equipped with appropriate fire suppression systems and gas detection equipment. Keep containers tightly sealed and protected from physical damage. Avoid storage near oxidizing agents, strong bases, and metals like aluminum or magnesium. Ensure storage areas comply with local regulations for flammable gases and maintain temperatures below 40°C to prevent excessive pressure buildup.

What to do in case of contact with chloromethane?

Chloromethane exposure requires immediate action: move the affected person to fresh air and keep them warm and at rest. For skin contact, remove contaminated clothing and flush the area with lukewarm water. In case of eye contact, rinse immediately with clean water for at least 15 minutes. If inhaled, provide fresh air and monitor breathing; administer oxygen if necessary. Seek immediate medical attention in all cases of exposure, informing medical personnel of the potential carcinogenic nature and specific properties of chloromethane.

How to dispose of chloromethane appropriately?

Chloromethane disposal must comply with local and international hazardous waste regulations due to its flammable and potentially carcinogenic properties. The compound should never be released directly into the environment or disposed of in regular waste streams. Professional waste management companies specialized in hazardous gas disposal should handle the process. Incineration at high temperatures in approved facilities is typically the preferred method. Empty containers must also be treated as hazardous waste and properly decontaminated before disposal.

How to transport chloromethane?

Chloromethane is classified under ADR Class 2 (Gases) for transportation purposes and must be transported in approved pressure containers designed for flammable gases. Vehicles must be equipped with appropriate placarding and emergency response information. Transportation requires trained personnel familiar with hazardous gas handling procedures. Ensure proper securing of containers to prevent movement during transport and avoid routes through populated areas when possible. Compliance with international dangerous goods regulations (IMDG, IATA) is mandatory for sea and air transport.

Is chloromethane subject to specific regulations?

Chloromethane is subject to comprehensive regulation under REACH as a registered substance and falls under CLP classification requirements with mandatory hazard labeling. It is regulated as a potential carcinogen (Category 2) requiring specific workplace exposure limits and health surveillance programs. The substance faces restrictions under various environmental protection regulations due to its ozone depletion potential. Industrial users must comply with emission control requirements and may need specific permits for handling and processing this compound in commercial operations.

Where to buy chloromethane in Europe?

Chloromethane is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. As a regulated substance requiring proper handling expertise, it should only be purchased from qualified chemical distributors who can provide appropriate technical documentation, safety data sheets, and transport arrangements. Professional suppliers ensure compliance with REACH registration requirements and provide the necessary regulatory support for industrial applications requiring this specialized chemical intermediate.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.