Bromomethane

CH3Br

bromomethane

CAS74-83-9
GHS04 Gefahrensymbol: Unter Druck stehende Gase – Gasflasche
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

Consulting for Bromomethane

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Identification

CAS Number
74-83-9
EC Number
200-813-2
UN Number
1062
Index Number
602-002-00-2
PubChem CID
6323

Physical-chemical properties

Molecular Formula
CH3Br
Molar Mass
94.94 g/mol
IUPAC Name
bromomethane

Chemical Identifiers

InChI
InChI=1S/CH3Br/c1-2/h1H3
InChI Key
GZUXJHMPEANEGY-UHFFFAOYSA-N

Overview

Bromomethane (CAS 74-83-9) is a halogenated alkane compound with significant industrial applications as a fumigant and methylating agent. This colorless gas, also known as methyl bromide, represents one of the simplest organobromine compounds with the molecular formula CH3Br and a molecular weight of 94.94 g/mol. Bromomethane has historically played a crucial role in various industrial processes, particularly in fumigation applications and chemical synthesis. The compound belongs to the same family of halogenated methanes as other methylating agents, sharing certain reactivity patterns with compounds like sulfuryl difluoride in fumigation applications, though each possesses distinct properties and regulatory considerations. The substance presents significant safety considerations, classified under multiple hazard categories including acute toxicity, mutagenicity, and specific target organ toxicity. Its classification as a Category 2 mutagen and Category 3 acute toxin requires stringent handling protocols and specialized equipment. The compound exhibits properties typical of compressed gases and demands careful attention to storage and transportation requirements under ADR Class 2 regulations. Industrial applications of bromomethane include its use as a methylating agent in pharmaceutical synthesis, as a fumigant in certain specialized applications where permitted by regulation, and as an intermediate in the production of various organic compounds. The compound's reactivity makes it valuable in chemical manufacturing processes requiring efficient methyl group transfer. Despite its industrial utility, bromomethane use is heavily regulated due to environmental and health concerns, with many traditional applications being phased out or restricted. OYSI provides technical-grade bromomethane to qualified industrial customers with appropriate handling capabilities and regulatory compliance.

Safety & Classification

Danger
Classification:

Press. Gas; Muta. 2; Acute Tox. 3 *; Acute Tox. 3 *; STOT SE 3; STOT RE 2 *; Skin Irrit. 2; Eye I...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H341

Suspected of causing genetic defects.

H331

Toxic if inhaled.

H301

Toxic if swallowed.

H335

May cause respiratory irritation.

H373

May cause damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H400

Very toxic to aquatic life.

H420

Harms public health and the environment by destroying ozone in the upper atmosphere.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1062
ADR Class2
Packing Group
Tunnel CodeC/D
Proper Shipping NameMethylbromid, unter Druck verflüssigt, Chlorpikrin <= 2 %
Marine PollutantNo

Frequently Asked Questions

What is bromomethane?

Bromomethane is a halogenated hydrocarbon compound with the chemical formula CH3Br and molecular weight of 94.94 g/mol. Also known as methyl bromide, it is classified as a pressurized gas with significant health hazards including mutagenicity and acute toxicity. This organobromine compound carries the GHS danger signal word and multiple hazard pictograms (GHS04, GHS06, GHS08, GHS09), indicating its serious safety considerations for industrial handling.

What are the physicochemical properties of bromomethane?

Bromomethane is a colorless gas at room temperature with a sweet, chloroform-like odor. It has a boiling point of 3.6°C and exists as a pressurized gas under normal conditions. The compound is moderately soluble in water and highly soluble in organic solvents like alcohol and ether. Its density is approximately 3.3 times that of air, causing it to accumulate in low-lying areas when released.

What is bromomethane used for?

Bromomethane serves primarily as a soil fumigant for pest control in agriculture, particularly for sterilizing soil before planting high-value crops. It is also used as a methylating agent in organic synthesis and as an intermediate in pharmaceutical manufacturing. Additionally, it finds applications in the production of other organobromine compounds and as a solvent in specialized industrial processes, though many uses have been restricted due to environmental concerns.

How to handle bromomethane safely?

Bromomethane requires strict safety protocols including supplied-air respiratory protection, chemical-resistant gloves, and full protective clothing due to its acute toxicity and skin irritation potential. Work should be conducted in well-ventilated areas or under fume extraction systems. Personnel must be trained in gas detection procedures and emergency response. Avoid skin and eye contact, and never work alone when handling this pressurized, toxic gas.

How to store bromomethane correctly?

Bromomethane must be stored in pressure-rated cylinders in cool, well-ventilated areas away from heat sources and incompatible materials like strong oxidizers and metals. Storage areas should be equipped with gas detection systems and maintained below 40°C to prevent excessive pressure buildup. Cylinders must be secured upright, properly labeled, and stored in designated areas with restricted access due to the compound's toxicity and mutagenic properties.

What to do in case of contact with bromomethane?

Bromomethane exposure requires immediate emergency response: remove the victim from the contaminated area to fresh air and provide oxygen if breathing difficulties occur. For skin contact, remove contaminated clothing and flush with water for at least 15 minutes. In case of eye contact, irrigate thoroughly with clean water. Seek immediate medical attention for all exposure routes, as this compound can cause serious systemic toxicity and requires professional medical evaluation.

How to dispose of bromomethane appropriately?

Bromomethane disposal must comply with hazardous waste regulations as it is classified as toxic and environmentally harmful. The compound should never be released to atmosphere due to its ozone-depleting properties. Disposal must be conducted through licensed hazardous waste contractors using approved thermal destruction methods. Empty containers retain hazardous residues and require professional handling. Consult local environmental authorities for specific disposal requirements in your region.

How to transport bromomethane?

Bromomethane is classified under ADR Class 2 (Gases) for transportation, requiring specialized pressure vessels and dangerous goods documentation. Transport must comply with dangerous goods regulations including proper labeling, placarding, and driver certification. Vehicles must be equipped with appropriate safety equipment and emergency response information. Only authorized carriers experienced in handling toxic gases should transport this material due to its acute toxicity and pressurized nature.

Is bromomethane subject to specific regulations?

Bromomethane faces extensive regulatory controls including REACH registration requirements, CLP hazard classification, and Montreal Protocol restrictions as an ozone-depleting substance. Many uses are banned or strictly controlled under EU regulations. The compound requires special permits for import/export and is subject to workplace exposure limits. Users must comply with SEVESO III directive requirements and maintain detailed records of usage and emissions due to its environmental and health impacts.

Where to buy bromomethane in Europe?

Bromomethane can be purchased through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous materials handling. As a regulated substance requiring special permits and safety documentation, procurement should only be through established suppliers who can ensure proper regulatory compliance, safety data sheets, and appropriate packaging. OYSI provides technical support and regulatory guidance for safe handling and application of this controlled chemical substance.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.