Bromobenzene
C6H5Br
bromobenzene
Consulting for Bromobenzene
Our experts support you with application, dosage, and compliance.
Identification
- CAS Number
- 108-86-1
- EC Number
- 203-623-8
- UN Number
- 2514
- Index Number
- 602-060-00-9
- PubChem CID
- 7961
Physical-chemical properties
- Molecular Formula
- C6H5Br
- Molar Mass
- 157.01 g/mol
- IUPAC Name
- bromobenzene
Chemical Identifiers
- InChI
- InChI=1S/C6H5Br/c7-6-4-2-1-3-5-6/h1-5H
- InChI Key
- QARVLSVVCXYDNA-UHFFFAOYSA-N
Overview
Bromobenzene (CAS 108-86-1) is an aromatic halogen compound featuring a bromine atom directly bonded to a benzene ring. This colorless to pale yellow liquid represents one of the most important aryl bromides in industrial chemistry, serving as a fundamental building block for numerous synthetic applications. With its molecular formula C6H5Br and molar mass of 157.01 g/mol, bromobenzene exhibits characteristic properties of aromatic halides, including moderate volatility and excellent chemical stability under normal conditions. The compound demonstrates flammable liquid properties classified under Flam. Liq. 3, requiring appropriate fire prevention measures during handling and storage. Safety considerations include potential skin irritation (Skin Irrit. 2) and environmental concerns related to aquatic toxicity (Aquatic Chronic 2). The GHS02, GHS07, and GHS09 pictograms indicate flame, health hazard, and environmental hazard classifications respectively, with a "Warning" signal word reflecting moderate risk levels. Bromobenzene finds extensive use in pharmaceutical synthesis as an intermediate for active pharmaceutical ingredients, particularly in coupling reactions and nucleophilic substitutions. The chemical industry utilizes it for manufacturing specialty chemicals, dyes, and agricultural compounds. Additionally, it serves as a solvent in specific applications where aromatic halides are preferred over conventional solvents like chlorobenzene, offering enhanced selectivity in certain reactions. The compound belongs to the broader family of halogenated aromatics, sharing structural similarities with chlorobenzene while providing different reactivity patterns due to the bromine substituent. Its ADR Class 3 classification requires compliance with transportation regulations for flammable liquids. OYSI maintains reliable supplies of high-quality bromobenzene to support diverse industrial applications across European markets.
Safety & Classification
Flam. Liq. 3; Skin Irrit. 2; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2514 |
| ADR Class | 3 |
| Packing Group | III |
| Tunnel Code | D/E |
| Proper Shipping Name | Brombenzen |
| Marine Pollutant | No |
Frequently Asked Questions
What is bromobenzene?
Bromobenzene is an aromatic halogenated compound with the molecular formula C6H5Br and CAS number 108-86-1. It consists of a benzene ring with one bromine atom substituted for a hydrogen atom. With a molecular weight of 157.01 g/mol, bromobenzene appears as a colorless to pale yellow liquid with a characteristic aromatic odor. It is classified as a flammable liquid and requires careful handling due to its skin irritation properties and potential environmental impact on aquatic organisms.
What are the physicochemical properties of bromobenzene?
Bromobenzene is a colorless to pale yellow liquid at room temperature with a distinctive sweet, aromatic odor typical of substituted benzenes. It has a molecular weight of 157.01 g/mol and is practically insoluble in water but readily soluble in organic solvents such as ethanol, ether, and acetone. The compound has a boiling point around 156°C and a density higher than water. Its aromatic structure makes it stable under normal conditions but flammable when exposed to ignition sources.
What is bromobenzene used for?
Bromobenzene is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a starting material for producing various chemicals through nucleophilic substitution reactions, Grignard reactions, and coupling reactions. The compound finds applications in the synthesis of dyes, agrochemicals, and specialty chemicals. It is also used as a solvent in certain industrial processes and as a reagent in laboratory research for organic chemistry applications, particularly in aromatic substitution reactions.
How to handle bromobenzene safely?
Bromobenzene requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation of vapors. As a flammable liquid (Class 3), keep away from heat sources, sparks, and open flames. Avoid direct skin contact as it can cause irritation. Use non-sparking tools and ensure proper grounding when transferring the material to prevent static electricity buildup.
How to store bromobenzene correctly?
Bromobenzene should be stored in a cool, dry, well-ventilated area away from heat sources, ignition sources, and direct sunlight. Keep containers tightly closed and use appropriate chemical-resistant materials for storage vessels. Store separately from strong oxidizing agents, strong bases, and reactive metals due to potential incompatibilities. Maintain storage temperatures below 25°C when possible and ensure adequate fire protection systems are in place. Follow local regulations for flammable liquid storage and maintain proper inventory management to prevent prolonged storage.
What to do in case of contact with bromobenzene?
In case of skin contact with bromobenzene, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, rinse immediately with clean water for 15 minutes and seek medical attention. If inhaled, move the person to fresh air and keep them at rest. In case of ingestion, do not induce vomiting and seek immediate medical attention. For all exposure incidents, contact emergency services if symptoms persist or worsen.
How to dispose of bromobenzene properly?
Bromobenzene must be disposed of as hazardous waste according to local and national environmental regulations. Never pour it down drains, onto soil, or into waterways due to its classification as Aquatic Chronic 2. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities can often be recovered through distillation for reuse. Empty containers should be handled as hazardous waste unless properly cleaned. Always consult local environmental authorities for specific disposal requirements and approved disposal facilities in your area.
How to transport bromobenzene?
Bromobenzene is classified as ADR Class 3 (flammable liquids), Packing Group III for transportation purposes. It must be packaged in UN-approved containers with proper labeling including the flammable liquid hazard label and environmental hazard marking. Transport vehicles must comply with ADR regulations for Class 3 substances, including appropriate fire extinguishing equipment and driver certification. Ensure proper documentation including transport documents and emergency response information. Avoid transport during extreme temperatures and ensure containers are properly secured to prevent movement and damage during transit.
Is bromobenzene subject to specific regulations?
Bromobenzene is subject to various chemical regulations including REACH registration requirements in the European Union and CLP classification as Flam. Liq. 3, Skin Irrit. 2, and Aquatic Chronic 2. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with workplace safety regulations, environmental discharge limits, and proper labeling requirements. Industrial users may need to implement risk management measures and safety data sheet provisions. Always check current regulatory status as chemical regulations may be updated periodically by authorities.
Where to buy bromobenzene in Europe?
Bromobenzene is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers across Europe. OYSI provides high-quality bromobenzene with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical distributor, OYSI ensures proper packaging, labeling, and transportation according to ADR regulations. Contact OYSI directly for availability, technical specifications, and pricing information. They can provide guidance on regulatory requirements and safe handling practices for your specific application needs.
Services for Bromobenzene
Order Bromobenzene
Fast delivery across Europe
SDS Service
Request Safety Data Sheet for Bromobenzene
Technical Consulting
Application advice for Bromobenzene
REACH Safety Data Sheet
REACH Compliance Service
Digital Product Passport
EU-compliant product documentation
ADR Consulting for Bromobenzene
Bromobenzene is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.