6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is an organic compound with the molecular formula C11H11FO2 and CAS number 99199-90-3. This fluorinated chromene derivative has a molecular weight of 194.2 g/mol and features both a fluorine substituent and an epoxide ring (oxirane). It is classified as a skin sensitizer and poses chronic aquatic hazards, requiring careful handling in industrial applications.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is a fluorinated organic compound with a molecular weight of 194.2 g/mol. The presence of the fluorine atom and epoxide functional group influences its reactivity and polarity. Specific physical properties such as melting point, boiling point, and solubility data would need to be determined experimentally or obtained from detailed technical specifications from the manufacturer.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is typically used as an intermediate in organic synthesis and pharmaceutical research. The compound's epoxide functionality makes it valuable for ring-opening reactions, while the fluorinated chromene structure can serve as a building block for developing bioactive molecules. Its applications are primarily in research laboratories and specialized chemical manufacturing processes requiring fluorinated intermediates.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene must be handled with appropriate personal protective equipment due to its skin sensitization properties. Wear chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid direct skin contact and implement proper hygiene measures. Follow standard laboratory safety protocols for handling sensitizing chemicals and ensure emergency procedures are readily available.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene should be stored in a cool, dry place away from heat sources and incompatible materials. Keep containers tightly sealed to prevent moisture absorption and contamination. Due to the epoxide functionality, avoid exposure to acids or bases that could catalyze ring-opening reactions. Store in appropriate secondary containment and ensure proper labeling according to GHS requirements with Warning signal word.

Immediate action is required upon contact with 6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene due to its skin sensitizing properties. For skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse with clean water for 15 minutes. Seek medical attention if irritation develops or persists. Remove the person from exposure area if inhalation occurs.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene must be disposed of as hazardous waste according to local and national environmental regulations. Do not discharge into drains, water courses, or onto the ground due to its chronic aquatic toxicity classification. Contact licensed waste disposal companies experienced in handling fluorinated organic compounds. Ensure proper waste characterization and documentation. Small laboratory quantities may require specific collection and treatment procedures.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation. Use appropriate UN specification packaging and ensure proper hazard labeling and documentation. Transport vehicles must comply with ADR requirements for Class 9 substances. Ensure drivers have appropriate training and emergency procedures are available. Avoid transport during extreme weather conditions and secure packages to prevent damage during transit.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is subject to standard chemical regulations under REACH and CLP in Europe. It is not currently listed as a Substance of Very High Concern (SVHC). The compound must be classified and labeled according to CLP regulation with appropriate hazard pictograms (GHS07, GHS09) and Warning signal word. Companies handling this substance must comply with occupational safety regulations and environmental protection requirements.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is available through OYSI, a specialized European distributor of fine chemicals and research compounds. OYSI provides this compound with appropriate documentation, safety data sheets, and regulatory compliance information. As a European supplier, OYSI ensures proper handling of import regulations and REACH requirements. Contact OYSI directly for availability, specifications, and ordering information for your specific research or industrial applications.