6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is an organic chemical compound with the molecular formula C11H11FO2 and CAS number 99199-90-3. This fluorinated chromene derivative contains both an epoxide (oxirane) ring and a dihydrochromene structure, giving it unique chemical properties. With a molecular weight of 194.2 g/mol, it is classified as a skin sensitizer and presents chronic aquatic toxicity, requiring careful handling in professional applications.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is a molecular compound with a molecular weight of 194.2 g/mol and formula C11H11FO2. The presence of fluorine and the epoxide ring significantly influence its reactivity and stability. As a chromene derivative, it likely exists as a liquid or solid at room temperature, though specific physical properties like melting point, boiling point, and solubility data would require detailed technical specifications from suppliers.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene serves as an important intermediate in organic synthesis and pharmaceutical research. The compound's epoxide functionality makes it valuable for ring-opening reactions, while the fluorinated chromene structure is useful in medicinal chemistry applications. It may be employed in the development of bioactive compounds, specialty chemicals, or as a building block for more complex molecular structures in research and development laboratories.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene requires careful handling due to its skin sensitization properties (Skin Sens. 1). Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Work should be conducted in well-ventilated areas or under fume hoods. Avoid direct skin contact and inhalation, and ensure proper training on handling procedures before use. Emergency eyewash and shower facilities should be readily accessible.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Due to the reactive epoxide group, avoid exposure to acids, bases, and nucleophiles that could cause ring-opening reactions. Store separately from oxidizing agents and maintain stable temperature conditions. Regular container inspection is recommended, and storage areas should comply with local chemical storage regulations and fire safety requirements.

Immediate action is required if contact occurs with 6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene due to its skin sensitizing properties. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, rinse immediately with clean water for 15-20 minutes and remove contact lenses if present. Seek medical attention promptly, especially if irritation persists. Keep the safety data sheet available for medical personnel.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene must be disposed of through authorized hazardous waste disposal services in accordance with local environmental regulations. Due to its aquatic chronic toxicity (Aquatic Chronic 2), it cannot be discharged into waterways or regular waste streams. Contact licensed chemical waste management companies for proper collection and treatment. Maintain detailed waste disposal records and ensure compliance with national and EU waste management directives including proper waste classification codes.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires appropriate hazardous material packaging, labeling, and documentation during transport. Shipping containers must meet UN specification standards for Packing Group III materials. Transport vehicles require proper placarding, and drivers need hazmat certification. Ensure compliance with international dangerous goods regulations including proper shipping names and emergency response information.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is regulated under the European CLP Regulation as indicated by its GHS classification (GHS07, GHS09 pictograms) with 'Warning' signal word. It falls under REACH registration requirements for chemical substances. The compound is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with workplace safety regulations, proper labeling requirements, and maintain safety data sheets. Regular monitoring of regulatory updates is recommended for compliance.

6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides professional-grade chemical supplies with proper documentation, safety data sheets, and regulatory compliance support. As experienced chemical distributors, they ensure appropriate packaging, labeling, and transport according to ADR Class 9 requirements. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.