5-chloro-2-(2,4-dichlorophenoxy)phenol

C12H7Cl3O2

CAS3380-34-5
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
3380-34-5
EC Number
222-182-2
UN Number
3077
Index Number
604-070-00-9
PubChem CID
5564

Physical-chemical properties

Molecular Formula
C12H7Cl3O2
Molar Mass
289.50 g/mol
IUPAC Name
5-chloro-2-(2,4-dichlorophenoxy)phenol

Chemical Identifiers

InChI
InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H
InChI Key
XEFQLINVKFYRCS-UHFFFAOYSA-N

Overview

5-chloro-2-(2,4-dichlorophenoxy)phenol (CAS 3380-34-5) is an organochlorine compound with antimicrobial and preservative properties. This chlorinated phenolic compound represents a specialized chemical intermediate widely utilized in industrial applications requiring antimicrobial efficacy. With its molecular formula C12H7Cl3O2 and molecular weight of 289.5 g/mol, 5-chloro-2-(2,4-dichlorophenoxy)phenol features a unique diphenyl ether structure containing three strategically positioned chlorine atoms that enhance its biological activity and chemical stability. The compound exhibits notable antimicrobial properties due to its phenolic structure and halogen substitution pattern, making it effective against various microorganisms. From a safety perspective, this substance requires careful handling as it presents moderate hazards including skin and eye irritation (GHS07 pictogram) and significant aquatic toxicity (GHS09 pictogram). The classification as Aquatic Acute 1 and Aquatic Chronic 1 indicates substantial environmental concerns, necessitating proper containment and disposal protocols. Its ADR Class 9 designation reflects its status as a miscellaneous dangerous substance for transport purposes. Primary industrial applications include use as a preservative in industrial formulations, an antimicrobial agent in specialized coatings, and as a chemical intermediate in pharmaceutical synthesis. Unlike simpler compounds such as 2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione, this phenoxy derivative offers enhanced stability and broader spectrum activity. The compound finds particular utility in applications where sustained antimicrobial action is required under challenging environmental conditions. OYSI maintains reliable supply chains for 5-chloro-2-(2,4-dichlorophenoxy)phenol, supporting European industrial customers with consistent quality and comprehensive technical documentation for regulatory compliance.

Safety & Classification

Warning
Classification:

Skin Irrit. 2; Eye Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameTriclosan
Marine PollutantNo

Frequently Asked Questions

What is 5-chloro-2-(2,4-dichlorophenoxy)phenol?

5-chloro-2-(2,4-dichlorophenoxy)phenol is an organochlorine compound with the molecular formula C12H7Cl3O2 and CAS number 3380-34-5. This chemical features a phenolic structure with multiple chlorine substituents, giving it a molecular weight of 289.5 g/mol. It belongs to the class of chlorinated phenoxy compounds and is classified as hazardous to both human health and the aquatic environment according to GHS regulations.

What are the physicochemical properties of 5-chloro-2-(2,4-dichlorophenoxy)phenol?

5-chloro-2-(2,4-dichlorophenoxy)phenol is a solid organochlorine compound at room temperature with a molecular weight of 289.5 g/mol. As a chlorinated phenolic compound, it typically appears as a crystalline solid with limited water solubility due to its hydrophobic chlorinated aromatic structure. The presence of multiple chlorine atoms and the phenolic hydroxyl group influence its chemical stability and reactivity patterns.

What is 5-chloro-2-(2,4-dichlorophenoxy)phenol used for?

5-chloro-2-(2,4-dichlorophenoxy)phenol is primarily used as an intermediate in chemical synthesis and pharmaceutical manufacturing. Its chlorinated phenoxy structure makes it valuable in the production of specialized organic compounds, particularly in research and development applications. The compound may also serve as a building block for more complex molecules in fine chemical synthesis, though specific industrial applications depend on individual manufacturing requirements.

How to handle 5-chloro-2-(2,4-dichlorophenoxy)phenol safely?

5-chloro-2-(2,4-dichlorophenoxy)phenol requires careful handling due to its skin and eye irritant properties. Workers must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or use local exhaust ventilation to minimize exposure. Avoid direct contact with skin and eyes, and prevent inhalation of dust particles. Always wash hands thoroughly after handling and follow established workplace safety protocols.

How to store 5-chloro-2-(2,4-dichlorophenoxy)phenol correctly?

5-chloro-2-(2,4-dichlorophenoxy)phenol should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly closed and store in original packaging or suitable chemical-resistant containers. Due to its aquatic toxicity classification, ensure storage areas have appropriate containment measures to prevent environmental release. Separate from incompatible materials and maintain proper inventory management to ensure material integrity.

What to do in case of contact with 5-chloro-2-(2,4-dichlorophenoxy)phenol?

5-chloro-2-(2,4-dichlorophenoxy)phenol contact requires immediate action due to its irritant properties. For skin contact, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush eyes with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if irritation persists or symptoms develop.

How to dispose of 5-chloro-2-(2,4-dichlorophenoxy)phenol properly?

5-chloro-2-(2,4-dichlorophenoxy)phenol disposal must comply with local and national hazardous waste regulations due to its environmental classification. The compound requires treatment as hazardous waste and cannot be disposed of in regular waste streams. Contact licensed hazardous waste disposal companies for proper collection and treatment. Incineration at appropriate high-temperature facilities is typically the preferred disposal method, ensuring complete destruction while preventing environmental contamination.

How to transport 5-chloro-2-(2,4-dichlorophenoxy)phenol?

5-chloro-2-(2,4-dichlorophenoxy)phenol is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Shipments must use UN-approved packaging and display proper hazard labels. Transport vehicles require appropriate placarding, and drivers must have dangerous goods training certification for legal compliance during road transport.

Is 5-chloro-2-(2,4-dichlorophenoxy)phenol subject to specific regulations?

5-chloro-2-(2,4-dichlorophenoxy)phenol is subject to European REACH regulation and CLP classification requirements. The compound is classified under GHS with Warning signal word, displaying pictograms GHS07 and GHS09 for health and environmental hazards respectively. While not currently listed as a Substance of Very High Concern (SVHC), it requires safety data sheets and proper hazard communication. Users must comply with occupational exposure limits and environmental protection measures.

Where to buy 5-chloro-2-(2,4-dichlorophenoxy)phenol in Europe?

5-chloro-2-(2,4-dichlorophenoxy)phenol is available through OYSI, a specialized European distributor of technical chemicals and intermediates. OYSI provides this compound with complete regulatory documentation, including safety data sheets and certificates of analysis. As professional chemical distributors, OYSI ensures compliance with European regulations and provides technical support for proper handling and application of this specialized organochlorine compound throughout European markets.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.