5-chloro-2-(2,4-dichlorophenoxy)phenol

C12H7Cl3O2

CAS3380-34-5
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
3380-34-5
EC Number
222-182-2
UN Number
3077
Index Number
604-070-00-9
PubChem CID
5564

Physical-chemical properties

Molecular Formula
C12H7Cl3O2
Molar Mass
289.50 g/mol
IUPAC Name
5-chloro-2-(2,4-dichlorophenoxy)phenol

Chemical Identifiers

InChI
InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H
InChI Key
XEFQLINVKFYRCS-UHFFFAOYSA-N

Overview

5-chloro-2-(2,4-dichlorophenoxy)phenol (CAS 3380-34-5) is an organochlorine compound featuring antimicrobial and preservative properties through its phenolic structure. This chlorinated phenolic derivative represents a specialized chemical intermediate widely utilized in industrial applications requiring antimicrobial efficacy. The compound's molecular structure, characterized by multiple chlorine substituents on interconnected phenolic rings, confers enhanced stability and biocidal activity compared to simpler phenolic compounds. Its systematic designation reflects the precise positioning of three chlorine atoms across the diphenyl ether backbone, which significantly influences both its chemical reactivity and biological properties. The substance exhibits moderate skin and eye irritation potential, classified under GHS pictograms GHS07 and GHS09, indicating both health hazards and environmental concerns. Its aquatic toxicity profile requires careful handling and disposal procedures, as the compound demonstrates both acute and chronic toxicity to aquatic organisms. The Warning signal word reflects its intermediate hazard level, necessitating appropriate personal protective equipment during handling operations. Primary industrial applications include formulation of antimicrobial agents, synthesis of specialized preservatives, and development of biocidal products for industrial hygiene. The compound serves as a key intermediate in manufacturing processes requiring controlled antimicrobial activity, particularly in environments where traditional preservatives prove insufficient. Its chemical stability makes it suitable for applications involving elevated temperatures or challenging chemical environments, similar to other organochlorine compounds like 2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione used in industrial processes. OYSI maintains reliable European supply chains for 5-chloro-2-(2,4-dichlorophenoxy)phenol, supporting diverse industrial customers with comprehensive technical documentation and regulatory compliance assistance.

Safety & Classification

Warning
Classification:

Skin Irrit. 2; Eye Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameTriclosan
Marine PollutantNo

Frequently Asked Questions

What is 5-chloro-2-(2,4-dichlorophenoxy)phenol?

5-chloro-2-(2,4-dichlorophenoxy)phenol is an organochlorine compound with the molecular formula C12H7Cl3O2 and CAS number 3380-34-5. This chemical substance has a molecular weight of 289.5 g/mol and belongs to the phenolic compounds family. It is characterized by the presence of three chlorine atoms and a phenoxy group in its structure, making it a chlorinated aromatic compound with specific chemical properties.

What are the physicochemical properties of 5-chloro-2-(2,4-dichlorophenoxy)phenol?

5-chloro-2-(2,4-dichlorophenoxy)phenol is a solid crystalline compound at room temperature with a molecular weight of 289.5 g/mol. As a chlorinated aromatic compound, it typically exhibits low water solubility due to its hydrophobic nature and multiple chlorine substituents. The compound is more soluble in organic solvents such as alcohols, acetone, and other polar organic media, which is characteristic of phenolic chlorinated compounds.

What is 5-chloro-2-(2,4-dichlorophenoxy)phenol used for?

5-chloro-2-(2,4-dichlorophenoxy)phenol is primarily used as an intermediate in chemical synthesis and pharmaceutical manufacturing. This compound serves as a building block for the production of more complex molecules in the pharmaceutical and agrochemical industries. Its chlorinated aromatic structure makes it valuable for developing biologically active compounds, including potential antimicrobial agents and other specialty chemicals requiring specific chlorinated phenolic structures.

How to handle 5-chloro-2-(2,4-dichlorophenoxy)phenol safely?

5-chloro-2-(2,4-dichlorophenoxy)phenol requires careful handling due to its skin and eye irritant properties (Skin Irrit. 2; Eye Irrit. 2). Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid generating dust and ensure immediate washing if skin contact occurs.

How to store 5-chloro-2-(2,4-dichlorophenoxy)phenol correctly?

5-chloro-2-(2,4-dichlorophenoxy)phenol should be stored in a cool, dry place away from direct sunlight and heat sources. The compound must be kept in tightly sealed, chemically compatible containers to prevent moisture absorption and contamination. Storage areas should be well-ventilated and equipped with appropriate spill containment measures. Due to its aquatic toxicity classification, special precautions must be taken to prevent environmental release during storage.

What to do in case of contact with 5-chloro-2-(2,4-dichlorophenoxy)phenol?

Immediate action is required upon contact with 5-chloro-2-(2,4-dichlorophenoxy)phenol due to its irritant properties. For skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately and consult a physician if symptoms persist.

How to dispose of 5-chloro-2-(2,4-dichlorophenoxy)phenol appropriately?

5-chloro-2-(2,4-dichlorophenoxy)phenol must be disposed of as hazardous waste according to local and national regulations due to its environmental classification (Aquatic Acute 1; Aquatic Chronic 1). The compound should never be discharged into sewers, waterways, or soil. Disposal must be conducted through licensed hazardous waste contractors who can ensure proper treatment, typically involving high-temperature incineration or other approved destruction methods for chlorinated organic compounds.

How to transport 5-chloro-2-(2,4-dichlorophenoxy)phenol?

5-chloro-2-(2,4-dichlorophenoxy)phenol is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires specific packaging standards and labeling according to dangerous goods regulations. Shipments must be properly documented with appropriate transport documents and emergency response information. The packaging must meet UN specification requirements and display the correct hazard labels including GHS07 and GHS09 pictograms.

Is 5-chloro-2-(2,4-dichlorophenoxy)phenol subject to specific regulations?

5-chloro-2-(2,4-dichlorophenoxy)phenol is subject to standard EU chemical regulations including REACH and CLP classifications but is not currently listed as a Substance of Very High Concern (SVHC). The compound must comply with standard registration, evaluation, and authorization requirements under REACH. Its classification as skin and eye irritant, along with aquatic toxicity properties, requires appropriate safety data sheets, labeling with Warning signal word, and compliance with occupational exposure limits where established.

Where to buy 5-chloro-2-(2,4-dichlorophenoxy)phenol in Europe?

5-chloro-2-(2,4-dichlorophenoxy)phenol is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound to industrial customers, research institutions, and pharmaceutical companies across Europe. As a professional chemical distributor, OYSI ensures proper handling, packaging, and documentation compliance with European regulations, providing customers with high-quality products and technical support for their specific applications and requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.