4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol

C25H18O2

CAS3236-71-3
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
3236-71-3
EC Number
406-950-6
UN Number
3077
Index Number
604-060-00-4
PubChem CID
76716

Physical-chemical properties

Molecular Formula
C25H18O2
Molar Mass
350.40 g/mol
IUPAC Name
4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol

Chemical Identifiers

InChI
InChI=1S/C25H18O2/c26-19-13-9-17(10-14-19)25(18-11-15-20(27)16-12-18)23-7-3-1-5-21(23)22-6-2-4-8-24(22)25/h1-16,26-27H
InChI Key
YWFPGFJLYRKYJZ-UHFFFAOYSA-N

Overview

4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol (CAS 3236-71-3) is an organic compound featuring a fluorene backbone with two hydroxyphenyl substituents, commonly used as a specialty chemical intermediate. This bisphenol derivative represents a distinctive class of aromatic compounds characterized by its fluorene core structure substituted with phenolic groups at the 9-position. The molecule's unique architecture, combining the rigid fluorene framework with reactive hydroxyl functionalities, imparts specific properties that make it valuable in various industrial applications. With a molecular formula of C25H18O2 and molecular weight of 350.4 g/mol, this compound exhibits the structural complexity typical of advanced organic intermediates used in polymer chemistry and materials science. From a safety perspective, 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol requires careful handling due to its classification as a skin and eye irritant (GHS07 pictogram) and its potential environmental impact on aquatic systems (GHS09 pictogram). The compound falls under ADR Class 9 for transportation, indicating it requires specific packaging and handling protocols during shipping and storage. Safety measures should include appropriate personal protective equipment and containment procedures to prevent environmental release. Industrial applications primarily focus on its role as a chemical intermediate in polymer synthesis, where its bifunctional nature allows for incorporation into various polymer backbones. The compound finds use in specialty resin formulations and as a building block for advanced materials requiring thermal stability and specific optical properties. Unlike simpler phenolic compounds or phosphite stabilizers such as triphenyl phosphite, this fluorene-based structure offers enhanced rigidity and unique performance characteristics in demanding applications. OYSI provides reliable access to 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol for European industrial customers requiring consistent quality and technical support for their specialized chemical processes.

Safety & Classification

Warning
Classification:

Skin Irrit. 2; Eye Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name9,9-Bis(4-hydroxyphenyl)fluoren
Marine PollutantNo

Frequently Asked Questions

What is 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol?

4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol is an organic chemical compound with the molecular formula C25H18O2 and CAS number 3236-71-3. This substance has a molecular weight of 350.4 g/mol and belongs to the fluorene derivative family. It is characterized by its biphenolic structure containing a central fluorene core with two hydroxyphenyl groups. The compound is classified as hazardous with skin and eye irritation properties, and poses risks to aquatic environments.

What are the physicochemical properties of 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol?

4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol typically appears as a solid crystalline material at room temperature due to its high molecular weight of 350.4 g/mol. The compound contains two hydroxyl groups that influence its solubility characteristics, making it moderately soluble in polar organic solvents and alcohols but poorly soluble in water. Its fluorene backbone provides structural rigidity and contributes to its thermal stability properties.

What is 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol used for?

4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol is primarily used as a chemical intermediate in pharmaceutical and fine chemical synthesis. Its biphenolic structure makes it valuable in polymer chemistry applications and as a building block for advanced materials. The compound may also find applications in research and development for specialty chemical formulations, particularly where fluorene-based structures are required for specific molecular properties.

How to handle 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol safely?

4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol must be handled with appropriate personal protective equipment including safety gloves, protective clothing, and eye protection due to its Skin Irrit. 2 and Eye Irrit. 2 classifications. Work should be conducted in well-ventilated areas or under fume hoods. Avoid direct contact with skin and eyes, and prevent inhalation of dust or vapors. The Warning signal word indicates moderate hazard levels requiring standard laboratory safety precautions.

How to store 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol correctly?

4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Given its aquatic toxicity classification (Aquatic Acute 1; Aquatic Chronic 1), storage areas must be designed to prevent environmental release. Keep containers properly labeled and away from incompatible materials. Regular inspection of storage containers is recommended to ensure integrity and prevent leakage.

What to do in case of contact with 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol?

Skin contact with 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of clean water for at least 15 minutes and seek medical attention. In case of inhalation, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for complete first aid procedures.

How to dispose of 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol appropriately?

4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol must be disposed of through licensed hazardous waste disposal facilities due to its aquatic toxicity classification. The substance cannot be discharged to sewers or waterways given its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Disposal must comply with local, national, and EU waste regulations. Contact certified waste management companies for proper collection, treatment, and disposal following the waste framework directive requirements.

How to transport 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol?

4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to ADR regulations. Packages must display the Class 9 hazard label and proper shipping name. Transportation should be conducted by qualified carriers familiar with dangerous goods regulations, with appropriate emergency response information readily available during transport.

Is 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol subject to special regulations?

4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol is subject to standard EU chemical regulations including REACH registration requirements and CLP classification and labeling obligations. The substance is not currently identified as a Substance of Very High Concern (SVHC) under REACH. However, its GHS07 and GHS09 pictogram classifications require compliance with occupational health and environmental protection measures. Users must ensure proper risk assessment and implementation of appropriate risk management measures.

Where to buy 4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol in Europe?

4-[9-(4-hydroxyphenyl)fluoren-9-yl]phenol is available through OYSI, a specialized European distributor of chemical products. OYSI provides this compound to industrial and research customers across Europe with proper documentation and regulatory compliance. As a professional chemical distributor, OYSI ensures quality standards, appropriate packaging, and regulatory compliance for hazardous materials transport. Contact OYSI directly for availability, specifications, and ordering information for your specific requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.