4-aminobenzenesulfonic acid
C6H7NO3S
Consulting for 4-aminobenzenesulfonic acid
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Identification
- CAS Number
- 121-57-3
- EC Number
- 204-482-5
- UN Number
- Index Number
- 612-014-00-X
- PubChem CID
- 8479
Physical-chemical properties
- Molecular Formula
- C6H7NO3S
- Molar Mass
- 173.19 g/mol
- IUPAC Name
- 4-aminobenzenesulfonic acid
Chemical Identifiers
- InChI
- InChI=1S/C6H7NO3S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H,8,9,10)
- InChI Key
- HVBSAKJJOYLTQU-UHFFFAOYSA-N
Overview
4-aminobenzenesulfonic acid (CAS 121-57-3) is an aromatic sulfonated compound with amino functionality and high water solubility. This organic compound, also known by its IUPAC designation 4-aminobenzenesulfonic acid, represents a significant intermediate in the chemical industry with molecular formula C6H7NO3S and molecular weight of 173.19 g/mol. The substance features both amino and sulfonic acid functional groups attached to a benzene ring, making it a versatile building block for various chemical syntheses. From a safety perspective, this compound requires careful handling due to its classification as Skin Irritant Category 2, Eye Irritant Category 2, and Skin Sensitizer Category 1, carrying the GHS07 pictogram and "Warning" signal word. Proper personal protective equipment including gloves, eye protection, and adequate ventilation are essential when working with this material. The dual functional groups present in its structure contribute to these irritation properties, similar to how compounds like 4-nitrophenol can exhibit comparable handling requirements due to their aromatic nature with reactive substituents. The compound finds primary applications in the pharmaceutical industry as an intermediate for drug synthesis, in dye manufacturing where its aromatic amino structure serves as a coupling component, and in the production of optical brightening agents for textile and paper industries. Its excellent water solubility makes it particularly valuable in aqueous processing environments where other aromatic compounds might present solubility challenges. OYSI maintains reliable European supply chains for 4-aminobenzenesulfonic acid, ensuring consistent quality and availability for industrial customers across various manufacturing sectors.
Safety & Classification
Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Frequently Asked Questions
What is 4-aminobenzenesulfonic acid?
4-aminobenzenesulfonic acid is an organic compound with the molecular formula C6H7NO3S and CAS number 121-57-3. This aromatic sulfonic acid derivative contains both amino and sulfonic acid functional groups on a benzene ring. With a molecular weight of 173.19 g/mol, it appears as a white to off-white crystalline powder. The compound is classified as a skin and eye irritant and potential skin sensitizer under GHS regulations.
What are the physicochemical properties of 4-aminobenzenesulfonic acid?
4-aminobenzenesulfonic acid is a white to off-white crystalline solid at room temperature with a molecular weight of 173.19 g/mol. The compound is highly soluble in water due to its sulfonic acid group, which provides strong ionic character. It exhibits typical aromatic compound stability while maintaining the reactivity of both amino and sulfonic acid functional groups. The substance is odorless and stable under normal storage conditions.
What is 4-aminobenzenesulfonic acid used for?
4-aminobenzenesulfonic acid is primarily used as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It serves as a key building block in the production of azo dyes and sulfonamide drugs. The compound is also utilized in analytical chemistry as a reagent and in the manufacture of optical brightening agents. Its dual functional groups make it valuable for various chemical modifications in industrial applications.
How to handle 4-aminobenzenesulfonic acid safely?
4-aminobenzenesulfonic acid requires careful handling due to its skin and eye irritation potential and skin sensitization properties. Wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation in work areas and avoid generating dust. Wash hands thoroughly after handling and avoid contact with skin, eyes, and clothing. Work in well-ventilated areas or use local exhaust ventilation systems.
How to store 4-aminobenzenesulfonic acid correctly?
4-aminobenzenesulfonic acid should be stored in tightly closed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers sealed when not in use to prevent moisture absorption and contamination. Store away from strong oxidizing agents and incompatible materials. Maintain storage temperatures below 25°C and ensure proper labeling according to GHS requirements. Regularly inspect containers for damage or deterioration.
What to do in case of contact with 4-aminobenzenesulfonic acid?
In case of skin contact with 4-aminobenzenesulfonic acid, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of clean water for at least 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if irritation persists or if allergic reactions develop, especially given its skin sensitization potential.
How to dispose of 4-aminobenzenesulfonic acid appropriately?
4-aminobenzenesulfonic acid must be disposed of in accordance with local, national, and international waste regulations. Contact licensed waste disposal companies for proper handling and treatment. Do not discharge into drains, waterways, or soil. Small quantities may require neutralization before disposal, while larger amounts need specialized chemical waste treatment. Maintain proper documentation of disposal activities and follow your facility's waste management procedures.
How to transport 4-aminobenzenesulfonic acid?
4-aminobenzenesulfonic acid does not appear to have specific ADR classification requirements, suggesting it may not be classified as dangerous goods for transport purposes. However, packages should be properly labeled according to GHS requirements with appropriate hazard pictograms and safety information. Ensure containers are securely closed and protected from damage during transport. Follow general chemical transport guidelines and maintain proper documentation including safety data sheets.
Is 4-aminobenzenesulfonic acid subject to specific regulations?
4-aminobenzenesulfonic acid is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification for hazard communication. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with workplace safety regulations, proper labeling requirements under GHS, and maintain safety data sheets. Industrial users should ensure compliance with local occupational exposure limits and reporting requirements.
Where to buy 4-aminobenzenesulfonic acid in Europe?
4-aminobenzenesulfonic acid is available through OYSI, a trusted European distributor of specialty chemicals serving various industries across the continent. OYSI provides high-quality chemical products with proper documentation, safety data sheets, and regulatory compliance support. Contact OYSI's technical team for product specifications, availability, and delivery options throughout Europe. Professional customers can rely on OYSI's expertise in chemical distribution and customer service.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.