4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline is a specialized organic compound with the molecular formula C14H17N5 and molecular weight of 255.32 g/mol. This heterocyclic aromatic amine contains both pyrazolo-triazole and aniline functional groups, making it valuable in pharmaceutical and chemical synthesis applications. The compound is identified by CAS number 152828-25-6 and features a complex bicyclic structure with a tert-butyl substituent.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline is a solid organic compound at room temperature with a molecular weight of 255.32 g/mol. The compound contains nitrogen-rich heterocyclic rings combined with an aromatic amine structure. Its physicochemical properties are influenced by the presence of multiple nitrogen atoms and the bulky tert-butyl group, which affect its solubility and stability characteristics in various solvents and reaction conditions.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline is primarily used as an intermediate in pharmaceutical synthesis and advanced chemical manufacturing. Its unique heterocyclic structure makes it valuable for developing bioactive compounds, particularly in medicinal chemistry research. The compound may also serve as a building block in the synthesis of specialized materials, dyes, or agrochemical products where its specific nitrogen-containing framework provides desired biological or chemical properties.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline requires careful handling due to its skin sensitization properties (Skin Sens. 1). Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to minimize exposure. Avoid direct skin contact and inhalation. The compound carries GHS07 pictogram indicating health hazards, so follow proper hygiene practices and wash hands thoroughly after handling.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline should be stored in a cool, dry place away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and contamination. Store in designated chemical storage areas with appropriate ventilation and spill containment measures. Due to its environmental classification (Aquatic Chronic 2), ensure storage areas have proper containment to prevent environmental release. Maintain proper inventory records and follow facility-specific storage protocols for organic chemicals.

Immediate action is required if contact occurs with 4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline due to its skin sensitizing properties. For skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, rinse immediately with clean water for 15 minutes while holding eyelids open. Seek medical attention if irritation persists or develops. For inhalation, move to fresh air immediately and seek medical advice if breathing difficulties occur.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline must be disposed of through licensed hazardous waste disposal companies due to its environmental classification (Aquatic Chronic 2). Never dispose of this substance down drains, in regular waste, or release to the environment. Collect waste in appropriate containers, properly labeled with contents and hazard information. Follow local and national environmental regulations for hazardous chemical waste disposal. Maintain disposal records as required by regulatory authorities and company procedures.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to ADR regulations. Use UN-approved packaging suitable for Class 9 substances and ensure proper hazard labels are affixed. Transport documentation must include correct shipping names, UN numbers, and hazard classifications. Only use qualified carriers experienced in handling chemical products under ADR regulations.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline is subject to standard European chemical regulations including REACH and CLP classifications. The compound is not currently listed as a Substance of Very High Concern (SVHC). It must be handled according to its CLP classification as Skin Sens. 1 and Aquatic Chronic 2, requiring appropriate risk management measures. Users must ensure compliance with workplace safety regulations, environmental protection laws, and proper chemical registration requirements under REACH when applicable.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline is available through OYSI, a leading European distributor of specialty chemicals and pharmaceutical intermediates. OYSI provides high-quality chemical products to research institutions, pharmaceutical companies, and industrial customers across Europe. As an established chemical distributor, OYSI ensures proper handling, documentation, and regulatory compliance for specialized compounds like this pyrazolo-triazole derivative. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.