4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline is a specialized organic compound with the molecular formula C14H17N5 and molecular weight 255.32 g/mol. This heterocyclic aromatic amine contains both pyrazolo-triazole and aniline functional groups, making it a versatile chemical intermediate. The compound is classified under CAS number 152828-25-6 and features a tert-butyl substituent that enhances its stability and modifies its reactivity profile for various synthetic applications.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline is a solid organic compound at room temperature with a molecular weight of 255.32 g/mol. The compound contains multiple nitrogen atoms within its heterocyclic structure, contributing to its chemical reactivity. Its tert-butyl group provides steric hindrance and affects solubility characteristics. Specific physical properties such as melting point, boiling point, and exact solubility data should be confirmed through detailed technical specifications or analytical testing.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline serves primarily as a chemical intermediate in pharmaceutical and fine chemical synthesis. Its unique pyrazolo-triazole structure makes it valuable for developing bioactive compounds, particularly in medicinal chemistry research. The aniline functionality allows for further derivatization through standard aromatic substitution reactions. This compound may also find applications in materials science, agrochemical development, and as a building block for more complex heterocyclic systems in specialized industrial processes.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline requires careful handling due to its skin sensitization properties (Skin Sens. 1). Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction systems to minimize inhalation exposure. Avoid direct skin and eye contact. Handle in accordance with GHS07 pictogram requirements and ensure proper training on chemical safety protocols before use.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline should be stored in a cool, dry place away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and contamination. Store separately from strong oxidizing agents and incompatible materials. Ensure storage areas are well-ventilated and equipped with appropriate spill containment measures. Given its environmental hazard classification (Aquatic Chronic 2), prevent release to the environment and maintain proper inventory records for regulatory compliance.

Skin contact with 4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes and seek medical attention. If inhaled, move to fresh air immediately. Due to the compound's skin sensitization potential, monitor for allergic reactions and seek medical advice if symptoms develop. Always consult the safety data sheet for complete first aid procedures.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline must be disposed of through licensed hazardous waste contractors in compliance with local environmental regulations. Due to its Aquatic Chronic 2 classification, prevent release to water systems or soil. Contaminated materials should be treated as hazardous waste. Small quantities may be suitable for high-temperature incineration at authorized facilities. Always check local and national waste disposal regulations, and maintain proper waste documentation for regulatory compliance and environmental protection.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Use UN-specification packaging and ensure proper hazard markings and transport documents are in place. Drivers must hold valid dangerous goods certification. Follow ADR requirements for loading, segregation, and emergency procedures during transport to ensure safety and regulatory compliance.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline falls under REACH registration requirements in Europe and must comply with CLP classification and labeling regulations. The compound is not currently listed as a Substance of Very High Concern (SVHC). Its Skin Sens. 1 and Aquatic Chronic 2 classifications require specific hazard communication through safety data sheets and appropriate labeling with GHS07 and GHS09 pictograms. Users must ensure compliance with occupational exposure limits and environmental protection measures.

4-(6-tert-butyl-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)aniline is available through OYSI, a leading European distributor of specialty chemicals. OYSI provides reliable supply chains across Europe with proper documentation, quality assurance, and regulatory compliance support. As specialists in fine and pharmaceutical chemicals, OYSI ensures appropriate packaging, handling, and delivery of this sensitive compound. Contact OYSI directly for pricing, availability, technical specifications, and delivery options to your location within Europe.