2,4-dihydroxy-N-(2-methoxyphenyl)benzamide

2,4-dihydroxy-N-(2-methoxyphenyl)benzamide is an organic chemical compound with the molecular formula C14H13NO4 and CAS number 129205-19-2. This benzamide derivative has a molecular weight of 259.26 g/mol and contains hydroxyl groups at positions 2 and 4 of the benzene ring, along with a methoxyphenyl substituent. It is classified as a skin sensitizer and presents chronic aquatic toxicity, requiring careful handling in industrial applications.

2,4-dihydroxy-N-(2-methoxyphenyl)benzamide is a solid compound at room temperature with a molecular weight of 259.26 g/mol. The presence of hydroxyl and methoxy functional groups influences its polarity and solubility characteristics. The compound's structure, featuring both hydrophilic hydroxyl groups and a hydrophobic aromatic system, affects its dissolution behavior in various solvents. Specific physical properties such as melting point and exact solubility data should be confirmed through technical documentation.

2,4-dihydroxy-N-(2-methoxyphenyl)benzamide is primarily used in specialized chemical synthesis and research applications. As a benzamide derivative with specific functional groups, it serves as an intermediate in pharmaceutical research, organic synthesis, and potentially in the development of bioactive compounds. Its particular structural features make it valuable for chemical modification reactions and as a building block in complex molecule synthesis within controlled laboratory and industrial environments.

2,4-dihydroxy-N-(2-methoxyphenyl)benzamide requires careful handling due to its skin sensitization properties (Skin Sens. 1 classification). Essential safety measures include wearing appropriate personal protective equipment such as chemical-resistant gloves, safety glasses, and protective clothing to prevent skin contact. Work in well-ventilated areas and avoid generating dust. The Warning signal word indicates moderate hazard level, but strict adherence to safety protocols is essential to prevent sensitization reactions.

2,4-dihydroxy-N-(2-methoxyphenyl)benzamide should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and properly labeled according to GHS requirements, displaying GHS07 and GHS09 pictograms. Store away from heat sources, direct sunlight, and moisture to maintain product stability. Ensure storage areas are equipped with appropriate spill containment measures and restrict access to trained personnel only. Regular inventory checks help maintain proper storage conditions.

Skin contact with 2,4-dihydroxy-N-(2-methoxyphenyl)benzamide requires immediate action due to its sensitization potential. Remove contaminated clothing and wash affected skin thoroughly with soap and water for at least 15 minutes. If irritation develops or persists, seek medical attention immediately. For eye contact, rinse immediately with clean water for 15 minutes and consult a physician. In case of inhalation, move to fresh air. Always consult the safety data sheet for complete first aid procedures.

2,4-dihydroxy-N-(2-methoxyphenyl)benzamide must be disposed of according to local and national hazardous waste regulations due to its environmental classification (Aquatic Chronic 2). Contact licensed waste disposal companies specialized in chemical waste management. Never dispose of this substance through regular waste streams or sewage systems. Contaminated packaging should also be treated as hazardous waste. Maintain proper documentation of disposal activities and follow all applicable environmental protection requirements for chemical waste handling.

2,4-dihydroxy-N-(2-methoxyphenyl)benzamide is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III, indicating moderate transport hazard. Use appropriate UN-approved packaging designed for Class 9 substances and ensure proper labeling with required hazard markings. Transport documentation must include the correct shipping name and UN number. Vehicles should be equipped with appropriate emergency equipment, and drivers must hold valid dangerous goods transport certification according to ADR regulations.

2,4-dihydroxy-N-(2-methoxyphenyl)benzamide is regulated under REACH and CLP regulations within the European Union, requiring proper classification and labeling with GHS07 and GHS09 pictograms. It is not currently listed as a Substance of Very High Concern (SVHC). Companies must comply with registration, evaluation, and authorization requirements under REACH. Transport is governed by ADR regulations as Class 9 dangerous goods, and environmental regulations apply due to its aquatic toxicity classification.

2,4-dihydroxy-N-(2-methoxyphenyl)benzamide is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with complete regulatory documentation, safety data sheets, and certificates of analysis to ensure compliance with European chemical regulations. As an established chemical distributor, OYSI offers reliable supply chain management and technical support for industrial customers requiring this specialized benzamide derivative for their applications across European markets.