3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate is a complex organic compound with molecular formula C20H25ClN2O5 and CAS number 88150-42-9. This dihydropyridine derivative has a molecular weight of 408.9 g/mol and belongs to a class of compounds often associated with calcium channel blocking activity. The molecule contains multiple functional groups including ethyl and methyl esters, an aminoethoxymethyl side chain, and a chlorinated phenyl ring attached to the dihydropyridine core structure.

This compound is an organic solid with a molecular weight of 408.9 g/mol and molecular formula C20H25ClN2O5. As a dihydropyridine derivative containing both polar (amino, ester) and nonpolar (chlorophenyl) functional groups, it likely exhibits moderate solubility in organic solvents and limited water solubility. The presence of the amino group suggests potential for salt formation with acids. The compound's stability and exact physical appearance would depend on storage conditions and purity grade.

This dihydropyridine derivative is primarily used in pharmaceutical research and development applications. Compounds of this structural class are commonly investigated for their potential calcium channel modulating properties and cardiovascular therapeutic effects. It may serve as a research intermediate, reference standard, or active pharmaceutical ingredient precursor in drug discovery programs. The specific aminoethoxymethyl substitution pattern suggests targeted pharmaceutical applications, though specific therapeutic uses would require detailed pharmacological studies and regulatory approval.

Safe handling requires strict safety protocols due to its Acute Tox. 3 and Eye Dam. 1 classifications. Always wear appropriate PPE including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction to avoid inhalation. Prevent skin and eye contact as the substance can cause severe eye damage. Use proper laboratory techniques, avoid eating, drinking, or smoking in work areas, and wash hands thoroughly after handling. Implement emergency procedures and ensure safety shower and eyewash stations are accessible.

Store this compound in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Use tightly sealed, properly labeled containers to prevent contamination and moisture absorption. Due to its hazardous classification, store in a designated chemical storage area with restricted access. Keep away from incompatible materials such as strong oxidizers and bases. Implement proper inventory management and regular inspection of storage conditions. Ensure storage area has appropriate spill containment and emergency equipment readily available.

In case of eye contact, immediately flush with plenty of water for at least 15 minutes and seek immediate medical attention due to Eye Dam. 1 classification. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. If inhaled, move person to fresh air and seek medical attention if symptoms develop. In case of ingestion, do not induce vomiting and seek immediate medical attention due to acute toxicity. Always provide the safety data sheet to medical personnel for proper treatment guidance.

Disposal must comply with local, national, and EU waste regulations due to its hazardous classification. This substance requires disposal as hazardous chemical waste through licensed waste management companies. Never dispose of via regular waste streams or sewage systems due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Collect waste in properly labeled, compatible containers and maintain detailed waste documentation. Consider incineration at authorized high-temperature facilities as the preferred disposal method for organic pharmaceutical compounds.

Transport is regulated under ADR Class 6.1, Packing Group I, indicating high toxicity requiring strict packaging and documentation requirements. Use UN-approved packaging suitable for Packing Group I substances, with proper hazard labels and shipping documents. Only authorized carriers trained in dangerous goods transport should handle shipments. Ensure packages are properly marked with UN number, proper shipping name, and hazard labels. Transport vehicles must carry appropriate emergency equipment and documentation. Follow all ADR regulations for route restrictions and driver certification requirements.

This substance is subject to EU CLP regulation due to its hazardous classifications (Acute Tox. 3, STOT RE 2, Eye Dam. 1, Aquatic toxicity). It falls under REACH registration requirements if manufactured or imported above threshold quantities. The compound is not currently listed as a SVHC (Substance of Very High Concern). As a pharmaceutical intermediate, it may also be subject to additional pharmaceutical regulations and good manufacturing practices. Users must comply with occupational safety regulations and environmental protection measures due to its hazardous properties.

OYSI is a reliable European distributor for this specialized pharmaceutical compound, offering professional chemical distribution services across Europe. As experienced suppliers of research chemicals and pharmaceutical intermediates, OYSI can provide this substance with proper documentation, safety data sheets, and regulatory compliance support. Our European network ensures efficient logistics and technical support for laboratory and research applications. Contact OYSI directly for availability, specifications, and delivery options tailored to your specific research requirements and regulatory needs.