4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
C15H16O2
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Identification
- CAS Number
- 80-05-7
- EC Number
- 201-245-8
- UN Number
- 3077
- Index Number
- 604-030-00-0
- PubChem CID
- 6623
Physical-chemical properties
- Molecular Formula
- C15H16O2
- Molar Mass
- 228.29 g/mol
- IUPAC Name
- 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
Chemical Identifiers
- InChI
- InChI=1S/C15H16O2/c1-15(2,11-3-7-13(16)8-4-11)12-5-9-14(17)10-6-12/h3-10,16-17H,1-2H3
- InChI Key
- IISBACLAFKSPIT-UHFFFAOYSA-N
Overview
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol (CAS 80-05-7) is a bisphenol compound with strong industrial applications and significant regulatory considerations due to its hazardous properties. This organic compound, commonly known as bisphenol A (BPA), represents one of the most widely produced industrial chemicals globally, with a molecular formula of C15H16O2 and a molecular weight of 228.29 g/mol. The substance features two phenolic rings connected by a propane bridge, giving it unique chemical stability and reactivity properties that make it valuable across multiple industrial sectors. The compound's hazard classification includes reproductive toxicity (Repr. 1B), specific target organ toxicity (STOT SE 3), serious eye damage (Eye Dam. 1), skin sensitization (Skin Sens. 1), and acute and chronic aquatic toxicity (Aquatic Acute 1; Aquatic Chronic 1). These classifications necessitate careful handling protocols and appropriate safety measures during storage, transportation, and processing. The substance carries the "Danger" signal word and requires ADR Class 9 transport classification, reflecting its potential environmental and health impacts. Primary industrial applications include polycarbonate plastic production, where it serves as a key monomer, and epoxy resin manufacturing for protective coatings and adhesives. The chemical industry also utilizes this compound in the synthesis of flame retardants and as an intermediate in various polymer formulations. Unlike simpler compounds such as benzene-1,4-diol, this bisphenol structure provides enhanced thermal stability and mechanical properties in final applications. Given the increasing regulatory scrutiny surrounding bisphenol compounds, proper documentation and compliance support are essential for industrial users. OYSI maintains technical-grade supplies of this compound with comprehensive regulatory documentation to support our European industrial clients' specific application requirements.
Safety & Classification
Repr. 1B; STOT SE 3; Eye Dam. 1; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
Health Hazard
GHS08
Serious health hazard. May cause cancer, organ damage, or genetic defects.
Exclamation Mark
GHS07
Harmful. May cause irritation, allergic reactions, or drowsiness.
Corrosion
GHS05
Corrosive. Causes severe skin burns and eye damage.
Environment
GHS09
Environmental hazard. Toxic to aquatic life with long lasting effects.
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | 4,4'-Isopropylidendiphenol |
| Marine Pollutant | No |
Frequently Asked Questions
What is 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol?
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol is an organic compound with the molecular formula C15H16O2 and CAS number 80-05-7. This phenolic compound has a molecular weight of 228.29 g/mol and features two hydroxyl groups attached to aromatic rings connected by a propane bridge. It is classified as a hazardous substance with reproductive toxicity, skin sensitization, and environmental concerns according to CLP regulation.
What are the physicochemical properties of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol?
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol typically appears as a white to off-white crystalline solid at room temperature. The compound has limited water solubility due to its phenolic structure but shows good solubility in organic solvents. Its molecular structure contains two phenolic hydroxyl groups, making it prone to oxidation and capable of forming hydrogen bonds, which influences its physical properties and stability.
What is 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol used for?
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol is primarily used as an antioxidant and stabilizer in polymer applications, particularly in the production of plastics and rubber materials. It serves as an intermediate in chemical synthesis and is utilized in the manufacturing of specialty chemicals. The compound's phenolic structure makes it effective at preventing oxidative degradation in various industrial formulations and materials.
How to handle 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol safely?
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol requires careful handling due to its classification as Repr. 1B, Eye Dam. 1, and Skin Sens. 1. Essential PPE includes chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction to avoid inhalation. Prevent skin and eye contact, and avoid generating dust. Ensure emergency eyewash stations and safety showers are accessible during handling operations.
How to store 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol correctly?
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers upright and properly labeled according to CLP requirements. Store away from incompatible materials such as strong oxidizing agents. Maintain storage temperatures below 25°C when possible and ensure adequate containment measures to prevent environmental release due to its aquatic toxicity classification.
What to do in case of contact with 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol?
Immediate action is required due to the compound's Eye Dam. 1 classification. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek immediate medical attention. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. If inhaled, move to fresh air immediately. Due to its reproductive toxicity classification, seek medical advice promptly for any significant exposure incident.
How to dispose of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol appropriately?
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol must be disposed of as hazardous waste due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Contact licensed waste disposal companies authorized to handle chemical waste. Never discharge to sewers, watercourses, or soil. Contaminated packaging should be treated as hazardous waste. Follow local and EU regulations including the Waste Framework Directive for proper classification and disposal documentation.
How to transport 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol?
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol is classified under ADR as Class 9 (Miscellaneous dangerous goods), Packing Group III. Transportation requires appropriate UN specification packaging and proper dangerous goods documentation. Vehicles must carry appropriate emergency equipment and drivers need ADR certification. Packages must display correct hazard labels and markings according to dangerous goods regulations. Ensure compliance with national and international transport regulations for hazardous materials.
Is 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol subject to specific regulations?
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol is subject to REACH regulation requiring registration for manufacture or import above one tonne annually. CLP classification mandates specific labeling with GHS08, GHS07, GHS05, and GHS09 pictograms and 'Danger' signal word. While not currently listed as SVHC, its Repr. 1B classification means it may face future regulatory scrutiny. Users must comply with occupational exposure limits and environmental discharge restrictions.
Where to buy 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol in Europe?
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to industrial customers across Europe with proper documentation including safety data sheets, certificates of analysis, and regulatory compliance information. As a professional chemical distributor, OYSI ensures proper packaging, labeling, and transport arrangements according to ADR and CLP requirements for this hazardous substance.
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4-[2-(4-hydroxyphenyl)propan-2-yl]phenol is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.