3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione
C8H8O3
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Identification
- CAS Number
- 26266-63-7
- EC Number
- 247-570-9
- UN Number
- 2698
- Index Number
- 607-099-00-5
- PubChem CID
- 6810
Physical-chemical properties
- Molecular Formula
- C8H8O3
- Molar Mass
- 152.15 g/mol
- IUPAC Name
- 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione
Chemical Identifiers
- InChI
- InChI=1S/C8H8O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-2,5-6H,3-4H2
- InChI Key
- KMOUUZVZFBCRAM-UHFFFAOYSA-N
Overview
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione (CAS 26266-63-7) is a cyclic anhydride compound with reactive carbonyl groups and benzofuran structure. This specialized organic compound, also identified by EC number 247-570-9, represents a unique class of heterocyclic anhydrides featuring a partially saturated benzofuran ring system. With its molecular formula C8H8O3 and molecular weight of 152.15 g/mol, this substance exhibits the characteristic reactivity of cyclic anhydrides while maintaining structural similarities to other complex organic intermediates used in chemical synthesis. The compound presents significant safety considerations requiring careful handling protocols. Classified with Eye Dam. 1, it causes serious eye damage and requires immediate protective measures during use. Its respiratory sensitization properties (Resp. Sens. 1) and skin sensitization potential (Skin Sens. 1) necessitate appropriate ventilation systems and personal protective equipment. The substance carries ADR Class 8 classification, indicating its corrosive nature during transport, while its aquatic chronic toxicity classification requires environmental protection measures. Industrial applications primarily focus on organic synthesis intermediates, where its anhydride functionality enables formation of esters, amides, and other derivatives. The compound serves as a valuable building block in pharmaceutical intermediates and specialty chemical manufacturing. Unlike simpler compounds such as ethane-1,2-diamine, this molecule's complex ring structure provides unique reactivity patterns essential for sophisticated synthetic pathways. The benzofuran backbone offers distinct advantages in materials science applications, particularly in polymer chemistry where controlled ring-opening reactions create specialized monomers. Its structural complexity allows for selective functionalization, making it valuable in fine chemical synthesis where precise molecular architecture is required. OYSI maintains reliable supply channels for this specialized anhydride, supporting European chemical manufacturers with consistent quality and regulatory compliance.
Safety & Classification
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1; Aquatic Chronic 3
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2698 |
| ADR Class | 8 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Tetrahydrophthalsäureanhydride, Maleinsäureanhydrid > 0,05 %, fest |
| Marine Pollutant | No |
Frequently Asked Questions
What is 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione?
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione is an organic chemical compound with the molecular formula C8H8O3 and CAS number 26266-63-7. This substance belongs to the benzofuran derivatives family and has a molecular weight of 152.15 g/mol. It is classified as a hazardous chemical requiring careful handling due to its potential to cause serious eye damage, respiratory sensitization, and skin sensitization effects.
What are the physicochemical properties of 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione?
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione is a solid organic compound at room temperature with the molecular formula C8H8O3. The substance has a molar mass of 152.15 g/mol and features a bicyclic structure containing both furan and benzene ring systems. Its exact physical properties such as melting point, boiling point, and solubility characteristics should be verified through technical datasheets for specific applications.
What is 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione used for?
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. The compound serves as a building block for the production of pharmaceuticals, specialty chemicals, and advanced materials. Its unique bicyclic structure makes it valuable for creating complex molecular architectures in research and development applications within the chemical industry.
How to handle 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione safely?
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione requires strict safety measures including wearing appropriate PPE such as safety goggles, chemical-resistant gloves, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct skin and eye contact, and ensure proper training on handling procedures. Emergency washing facilities should be readily accessible when working with this substance.
How to store 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione correctly?
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep the substance away from incompatible materials and ensure proper labeling according to GHS requirements. Storage areas should have appropriate spill containment measures and be accessible only to trained personnel. Regular inspection of containers for integrity is recommended.
What to do in case of contact with 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione?
Immediate action is required for contact with 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione due to its eye-damaging and skin-sensitizing properties. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention. For skin contact, wash thoroughly with soap and water. If inhaled, move to fresh air immediately. Remove contaminated clothing and seek medical advice if symptoms develop.
How to dispose of 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione properly?
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione must be disposed of according to local and national waste regulations as hazardous chemical waste. Do not discharge into drains, waterways, or the environment due to its chronic aquatic toxicity classification. Contact licensed waste disposal companies for proper treatment and disposal. Ensure waste containers are properly labeled and segregated from other waste streams following regulatory requirements.
How to transport 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione?
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione is classified under ADR Class 8 (corrosive substances) Packing Group III for transportation. The substance requires appropriate UN-specification packaging and proper hazard labeling during transport. Shipping documents must include the correct technical name, UN number, and hazard class. Ensure compliance with international transport regulations and use qualified carriers experienced in handling corrosive chemical substances.
Is 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione subject to specific regulations?
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione is not currently listed as a Substance of Very High Concern (SVHC) under REACH regulation. However, it must comply with CLP classification requirements as Eye Dam. 1, Resp. Sens. 1, Skin Sens. 1, and Aquatic Chronic 3. Users must ensure proper hazard communication, safety data sheet availability, and compliance with occupational exposure limits where applicable.
Where to buy 3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione in Europe?
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione is available through OYSI, a European distributor of specialty chemicals and technical products. OYSI provides reliable supply chains across Europe with proper regulatory compliance and technical support. Contact OYSI directly for availability, specifications, packaging options, and delivery to your location. Ensure your application requirements match the product specifications and regulatory status before ordering.
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3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.