Cyanamide

CH2N2

cyanamide

CAS420-04-2
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
420-04-2
EC Number
206-992-3
UN Number
2923
Index Number
615-013-00-2
PubChem CID
9864

Physical-chemical properties

Molecular Formula
CH2N2
Molar Mass
42.04 g/mol
IUPAC Name
cyanamide

Chemical Identifiers

InChI
InChI=1S/CH2N2/c2-1-3/h2H2
InChI Key
XZMCDFZZKTWFGF-UHFFFAOYSA-N

Overview

Cyanamide (CAS 420-04-2) is a nitrogen-containing organic compound with strong alkaline properties and high reactivity toward water and acids. This crystalline white solid, with the molecular formula CH2N2, represents one of the most versatile yet hazardous chemicals in industrial applications. Cyanamide exhibits exceptional reactivity due to its unique structure containing both amino and nitrile functional groups, making it a valuable intermediate in numerous chemical synthesis processes. The compound readily absorbs moisture from air and reacts vigorously with water, releasing ammonia and forming various derivatives. From a safety perspective, cyanamide requires stringent handling protocols due to its classification as a Category 2 carcinogen and reproductive toxicant. The substance presents significant risks including acute toxicity through oral and dermal exposure, severe skin and eye corrosion, and potential for skin sensitization. Its corrosive nature, indicated by the GHS05 pictogram alongside toxicity warnings GHS08 and GHS06, demands specialized storage conditions and comprehensive personal protective equipment during handling. Transport regulations classify it under ADR Class 8 as a corrosive substance. Industrial applications of cyanamide span pharmaceutical synthesis, agrochemical production, and specialty chemical manufacturing. The compound serves as a crucial building block for producing guanidine derivatives and various heterocyclic compounds. In agricultural chemistry, it functions as an intermediate for herbicide synthesis, while the pharmaceutical industry utilizes it for developing active pharmaceutical ingredients. Unlike more complex nitrogen compounds such as pentachloro-lambda5-phosphane, cyanamide's relatively simple structure facilitates its use in diverse synthetic pathways. OYSI provides high-quality cyanamide to European industrial customers, ensuring compliance with all relevant safety and regulatory requirements for this critical chemical intermediate.

Safety & Classification

Danger
Classification:

Carc. 2; Repr. 2; Acute Tox. 3; Acute Tox. 3; STOT RE 2; Skin Corr. 1; Eye Dam. 1; Skin Sens. 1; ...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H314

Causes severe skin burns and eye damage.

H318

Causes serious eye damage.

H317

May cause an allergic skin reaction.

H412

Harmful to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2923
ADR Class8
Packing GroupIII
Tunnel CodeE
Proper Shipping NameCyanamid, fest
Marine PollutantNo

Frequently Asked Questions

What is cyanamide?

Cyanamide is an organic compound with the chemical formula CH2N2 and molecular weight of 42.04 g/mol. It is a nitrogen-containing chemical that serves as an important industrial intermediate and agricultural product. This substance is classified as hazardous due to its corrosive properties, potential carcinogenic effects, and reproductive toxicity. Cyanamide requires careful handling due to its multiple health hazards including acute toxicity and skin sensitization properties.

What are the physicochemical properties of cyanamide?

Cyanamide is typically a white crystalline solid at room temperature with hygroscopic properties, meaning it readily absorbs moisture from air. The compound is highly soluble in water and polar solvents, forming alkaline solutions. It has a characteristic ammonia-like odor and can decompose upon heating or in the presence of acids. The substance is stable under normal conditions but can polymerize or decompose when exposed to high temperatures or certain catalysts.

What is cyanamide used for?

Cyanamide is primarily used as an agricultural chemical, particularly as a plant growth regulator and soil treatment agent in viticulture and horticulture. It serves as an important intermediate in the synthesis of pharmaceuticals, including guanidine derivatives and other nitrogen-containing compounds. The substance is also utilized in the production of melamine, dicyandiamide, and various organic chemicals. Additionally, it finds applications in the manufacturing of plastics, resins, and specialty chemicals.

How to handle cyanamide safely?

Cyanamide requires extensive personal protective equipment including chemical-resistant gloves, safety goggles, and full-face respiratory protection due to its corrosive and toxic nature. Workers must wear acid-resistant clothing and work in well-ventilated areas or under fume extraction systems. Avoid skin and eye contact completely, as the substance causes severe burns and permanent eye damage. Handle only with proper training and ensure emergency shower and eyewash stations are readily accessible.

How to store cyanamide correctly?

Cyanamide must be stored in tightly sealed, corrosion-resistant containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep separated from acids, oxidizing agents, and incompatible materials to prevent dangerous reactions. Storage areas should be equipped with appropriate spill containment measures and restricted access. Maintain temperatures below 25°C and protect from moisture to prevent decomposition. Regular container inspection is essential due to the corrosive nature of the substance.

What to do in case of contact with cyanamide?

Cyanamide contact requires immediate emergency response due to its severe corrosive properties. For skin contact, immediately flush with copious amounts of water for at least 15 minutes while removing contaminated clothing. In case of eye exposure, rinse continuously with water for at least 15 minutes and seek immediate medical attention. If inhaled, move the person to fresh air and provide oxygen if breathing is difficult. Never induce vomiting if ingested and obtain emergency medical care immediately.

How to dispose of cyanamide appropriately?

Cyanamide disposal must comply with local and European waste regulations as it is classified as hazardous waste. The substance cannot be disposed of in regular waste streams and requires specialized treatment at authorized hazardous waste facilities. Small quantities can be neutralized carefully under controlled conditions by qualified personnel before disposal. Container disposal must also follow hazardous waste protocols. Always consult local environmental authorities and waste management companies for specific disposal requirements and procedures.

How to transport cyanamide?

Cyanamide is classified under ADR regulations as Class 8 (corrosive substances), Packing Group III, requiring appropriate hazardous goods packaging and labeling. Transportation must comply with dangerous goods regulations including proper packaging, marking, and documentation. Vehicles must display appropriate hazard placards and drivers require ADR training certification. The substance must be secured to prevent movement during transport and separated from incompatible materials. Emergency response information must accompany all shipments.

Is cyanamide subject to specific regulations?

Cyanamide is subject to comprehensive European chemical regulations under REACH and CLP, requiring safety data sheets and hazard classification. The substance is classified as Category 2 carcinogen and reproductive toxicant, triggering strict workplace exposure limits and authorization requirements. It falls under dangerous goods regulations for transport and storage. Users must comply with occupational health and safety directives, and industrial emissions may be regulated under environmental protection laws depending on usage quantities and applications.

Where to buy cyanamide in Europe?

Cyanamide is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. As a hazardous substance requiring expert handling, it is essential to source from qualified suppliers who provide proper documentation, safety data sheets, and regulatory compliance support. OYSI ensures reliable supply chain management and technical support for industrial applications. Due to regulatory requirements, purchases typically require end-user declarations and appropriate licensing for handling hazardous chemicals.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.