3,4-dihydro-2H-pyran-2-carbaldehyde

C6H8O2

CAS100-73-2

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Identification

CAS Number
100-73-2
EC Number
202-884-5
UN Number
2607
PubChem CID
60994

Physical-chemical properties

Molecular Formula
C6H8O2
Molar Mass
112.13 g/mol
IUPAC Name
3,4-dihydro-2H-pyran-2-carbaldehyde

Chemical Identifiers

InChI
InChI=1S/C6H8O2/c7-5-6-3-1-2-4-8-6/h2,4-6H,1,3H2
InChI Key
NPWYTMFWRRIFLK-UHFFFAOYSA-N

Overview

3,4-dihydro-2H-pyran-2-carbaldehyde (CAS 100-73-2) is a cyclic aldehyde compound with distinctive heterocyclic structure and aldehyde functionality. This organic compound belongs to the pyran family, featuring a six-membered ring containing one oxygen atom and an aldehyde group at the 2-position. With the molecular formula C6H8O2 and a molecular weight of 112.13 g/mol, this substance presents unique chemical properties that make it valuable for various industrial applications. The compound is also known by its EC number 202-884-5 and is classified under ADR transport class 3, indicating its flammable nature. The heterocyclic structure of 3,4-dihydro-2H-pyran-2-carbaldehyde provides distinctive reactivity patterns, particularly through its aldehyde functional group, which readily participates in condensation reactions, oxidation processes, and nucleophilic additions. The partially saturated pyran ring system offers additional synthetic versatility compared to simpler aldehydes or fully saturated compounds. This structural combination is less common than linear aldehydes such as 2,2,5-trimethylhex-4-enal, making it particularly valuable for specialized synthetic applications. In industrial applications, this compound serves primarily as an intermediate in organic synthesis, particularly in pharmaceutical manufacturing and fine chemical production. It is utilized in the synthesis of complex heterocyclic compounds and as a building block for various pharmaceutical intermediates. The compound also finds application in specialty fragrance chemistry, where its unique structure contributes to distinctive olfactory properties. Safety handling requires standard precautions for flammable organic compounds, with appropriate ventilation and fire prevention measures essential due to its ADR class 3 classification. Storage should follow guidelines for aldehydes, protecting from oxidation and maintaining temperature control. OYSI provides reliable supply of 3,4-dihydro-2H-pyran-2-carbaldehyde to support European industrial operations requiring this specialized heterocyclic aldehyde.

Safety & Classification

No Hazard Classification

This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.

Transport (ADR)

UN Number2607
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameAcrolein, Dimer, stabilisiert
Marine PollutantNo

Frequently Asked Questions

What is 3,4-dihydro-2H-pyran-2-carbaldehyde?

3,4-dihydro-2H-pyran-2-carbaldehyde is an organic compound with the molecular formula C6H8O2 and CAS number 100-73-2. It belongs to the pyran family, featuring a six-membered heterocyclic ring containing one oxygen atom and an aldehyde functional group. With a molecular weight of 112.13 g/mol, this compound is commonly used as an intermediate in organic synthesis and pharmaceutical applications due to its reactive aldehyde group and cyclic structure.

What are the physicochemical properties of 3,4-dihydro-2H-pyran-2-carbaldehyde?

3,4-dihydro-2H-pyran-2-carbaldehyde is typically a colorless to pale yellow liquid at room temperature with a characteristic aldehyde odor. The compound exhibits moderate volatility and is soluble in organic solvents such as ethanol, methanol, and acetone, while having limited solubility in water. Its boiling point and other specific physical properties depend on purity and environmental conditions, making proper characterization essential for industrial applications.

What is 3,4-dihydro-2H-pyran-2-carbaldehyde used for?

3,4-dihydro-2H-pyran-2-carbaldehyde serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It is utilized in the production of various heterocyclic compounds, agrochemicals, and fine chemicals. The compound's reactive aldehyde functionality makes it valuable for condensation reactions, cyclizations, and other synthetic transformations. Additionally, it finds applications in fragrance and flavor chemistry due to its structural characteristics and potential aromatic properties.

How to handle 3,4-dihydro-2H-pyran-2-carbaldehyde safely?

Safe handling of 3,4-dihydro-2H-pyran-2-carbaldehyde requires standard laboratory safety practices including wearing appropriate personal protective equipment such as safety goggles, gloves, and lab coats. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation exposure. Avoid contact with skin, eyes, and clothing. Use proper grounding techniques when transferring the material to prevent static electricity buildup, and keep away from heat sources and open flames.

How to store 3,4-dihydro-2H-pyran-2-carbaldehyde correctly?

3,4-dihydro-2H-pyran-2-carbaldehyde should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. The storage area should be kept below 25°C to maintain product stability. Keep containers away from oxidizing agents and strong acids or bases that could cause unwanted reactions. Regular inspection of containers for leaks or deterioration is recommended, and inventory should follow first-in-first-out rotation principles.

What to do in case of contact with 3,4-dihydro-2H-pyran-2-carbaldehyde?

In case of skin contact with 3,4-dihydro-2H-pyran-2-carbaldehyde, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, flush thoroughly with clean water for 15 minutes and seek medical attention. If inhaled, move the person to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Remove contaminated clothing and wash before reuse. Always consult the safety data sheet for specific emergency procedures.

How to dispose of 3,4-dihydro-2H-pyran-2-carbaldehyde properly?

Disposal of 3,4-dihydro-2H-pyran-2-carbaldehyde must comply with local, national, and EU waste regulations. The compound should be treated as hazardous chemical waste and disposed of through licensed waste management companies specialized in organic chemical disposal. Never dispose of it down drains or in regular trash. Small quantities may be suitable for controlled incineration at appropriate facilities. Always consult local environmental authorities and waste disposal regulations before disposal.

How to transport 3,4-dihydro-2H-pyran-2-carbaldehyde?

3,4-dihydro-2H-pyran-2-carbaldehyde is classified under ADR Class 3 (flammable liquids), Packing Group III for transportation purposes. It must be packaged in appropriate UN-approved containers and labeled according to ADR regulations. Transport vehicles must comply with ADR requirements for Class 3 substances, including proper placarding and driver certification. Shipping documentation must include proper shipping names, hazard classes, and UN numbers. Only qualified carriers experienced in hazardous materials transport should handle shipments.

Is 3,4-dihydro-2H-pyran-2-carbaldehyde subject to specific regulations?

3,4-dihydro-2H-pyran-2-carbaldehyde is subject to standard EU chemical regulations including REACH (Registration, Evaluation, Authorization of Chemicals) and CLP (Classification, Labelling and Packaging) requirements. It is not currently listed as a Substance of Very High Concern (SVHC). Manufacturers and importers must ensure proper registration under REACH for quantities above one tonne per year. Standard industrial chemical handling and workplace safety regulations apply, along with environmental protection requirements for emissions and waste management.

Where to buy 3,4-dihydro-2H-pyran-2-carbaldehyde in Europe?

3,4-dihydro-2H-pyran-2-carbaldehyde is available through OYSI, a reliable European distributor of specialty chemicals and intermediates. OYSI provides high-quality chemical products to industries across Europe with comprehensive technical support and regulatory compliance documentation. As an established chemical distributor, OYSI ensures proper handling, storage, and transportation of chemicals while maintaining competitive pricing and reliable supply chains. Contact OYSI directly for availability, specifications, and pricing information for your specific requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.