3,4-dihydro-2H-pyran-2-carbaldehyde

3,4-dihydro-2H-pyran-2-carbaldehyde is an organic chemical compound with the molecular formula C6H8O2 and CAS number 100-73-2. This aldehyde features a six-membered heterocyclic ring containing one oxygen atom in a dihydropyran structure with an aldehyde functional group. With a molecular weight of 112.13 g/mol, it serves as an important intermediate in organic synthesis and pharmaceutical applications.

3,4-dihydro-2H-pyran-2-carbaldehyde is typically a colorless to pale yellow liquid at room temperature with a characteristic aldehyde odor. The compound exhibits moderate solubility in organic solvents such as ethanol, acetone, and dichloromethane, while showing limited solubility in water due to its organic nature. Its aldehyde functionality makes it reactive toward nucleophiles and prone to oxidation under certain conditions.

3,4-dihydro-2H-pyran-2-carbaldehyde is primarily used as an intermediate in pharmaceutical synthesis and fine chemical manufacturing. It serves as a building block for producing various heterocyclic compounds and bioactive molecules. The compound finds applications in the synthesis of natural product analogs, drug intermediates, and specialty chemicals in research and development laboratories as well as commercial pharmaceutical production.

3,4-dihydro-2H-pyran-2-carbaldehyde should be handled with standard laboratory safety precautions including wearing appropriate personal protective equipment such as safety glasses, chemical-resistant gloves, and lab coats. Work in well-ventilated areas or under fume hoods to avoid inhalation of vapors. Avoid contact with skin and eyes, and prevent ingestion. Keep away from sources of ignition as the compound is classified under ADR Class 3 (flammable liquids).

3,4-dihydro-2H-pyran-2-carbaldehyde should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers in fireproof storage areas due to its flammable nature (ADR Class 3). Store away from strong oxidizing agents and bases that could react with the aldehyde group. Maintain storage temperature below 25°C and ensure proper labeling of containers.

In case of skin contact with 3,4-dihydro-2H-pyran-2-carbaldehyde, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air and seek medical help if symptoms persist. In case of ingestion, do not induce vomiting and seek immediate medical attention.

3,4-dihydro-2H-pyran-2-carbaldehyde must be disposed of according to local and national environmental regulations as hazardous waste. Contact licensed waste disposal companies for proper treatment and disposal. Do not pour down drains or release into the environment. Small laboratory quantities should be collected in appropriate waste containers and labeled clearly. Incineration at authorized facilities under controlled conditions is typically the preferred disposal method for organic compounds.

3,4-dihydro-2H-pyran-2-carbaldehyde is classified under ADR Class 3 (flammable liquids), Packing Group III for transportation purposes. It must be packaged in UN-approved containers with appropriate labeling and documentation. Transportation requires compliance with dangerous goods regulations including proper marking, placarding of vehicles, and driver certification. Ensure containers are properly sealed and secured to prevent leakage during transit.

3,4-dihydro-2H-pyran-2-carbaldehyde is subject to standard chemical regulations including REACH registration requirements in Europe. The compound is not classified as a Substance of Very High Concern (SVHC) and does not carry specific GHS hazard classifications. However, it must comply with general chemical safety regulations, workplace exposure limits, and transportation requirements under ADR. Users should maintain safety data sheets and follow good laboratory practices.

3,4-dihydro-2H-pyran-2-carbaldehyde is available through OYSI, a specialized European distributor of technical chemicals and laboratory reagents. OYSI provides high-quality chemical products to pharmaceutical companies, research institutions, and industrial manufacturers across Europe. Contact OYSI directly for availability, specifications, packaging options, and delivery information to meet your specific requirements for this fine chemical intermediate.