3-chloropropanoic acid

3-chloropropanoic acid is an organochlorine compound with the molecular formula C3H5ClO2 and CAS number 107-94-8. This chemical features a three-carbon carboxylic acid chain with a chlorine atom attached to the terminal carbon. With a molecular weight of 108.52 g/mol, it serves as an important intermediate in organic synthesis and pharmaceutical manufacturing, offering unique reactivity due to the presence of both carboxylic acid and chloroalkyl functional groups.

3-chloropropanoic acid is typically a colorless to pale yellow liquid or crystalline solid at room temperature. It exhibits good solubility in water and polar organic solvents due to its carboxylic acid functionality. The compound has a characteristic acidic odor and demonstrates typical carboxylic acid behavior with a pKa around 4. Its chloroalkyl structure makes it reactive toward nucleophiles, and it can undergo typical esterification, amidation, and substitution reactions.

3-chloropropanoic acid serves as a versatile intermediate in organic synthesis, particularly in pharmaceutical and agrochemical manufacturing. It is commonly used for producing various derivatives through nucleophilic substitution reactions, where the chlorine atom can be replaced with different functional groups. The compound also finds applications in polymer chemistry, as a building block for specialty chemicals, and in research laboratories for synthetic organic chemistry projects requiring halogenated carboxylic acid intermediates.

3-chloropropanoic acid should be handled with standard laboratory safety precautions including wearing appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and lab coats. Work in well-ventilated areas or under fume hoods to avoid inhalation of vapors. Avoid skin and eye contact, and prevent ingestion. Use proper handling techniques to minimize spills and ensure all containers are properly labeled and sealed when not in use.

3-chloropropanoic acid should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers upright and properly labeled with hazard information. Store away from incompatible materials such as strong bases, oxidizing agents, and reactive metals. Maintain storage temperatures as recommended by the supplier and ensure containers are made of compatible materials that resist corrosion from acidic substances.

In case of skin contact with 3-chloropropanoic acid, immediately remove contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes. For eye contact, flush eyes with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and monitor breathing. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for specific first aid measures.

3-chloropropanoic acid waste must be disposed of according to local, national, and international environmental regulations. Do not pour down drains or release into the environment. Collect waste in appropriate containers and arrange disposal through licensed waste management companies specialized in chemical waste. Consider neutralization procedures where appropriate and permitted. Maintain proper documentation of waste disposal activities and follow your facility's waste management procedures for halogenated organic compounds.

3-chloropropanoic acid is classified under ADR Class 8 (Corrosive substances), Packing Group II, indicating it requires specific transport regulations for corrosive materials. It must be packaged in UN-approved containers suitable for corrosive substances and properly labeled with appropriate hazard markings. Transport documents must include proper shipping names and hazard classifications. Only use transport companies experienced in handling corrosive chemicals and ensure compliance with international dangerous goods regulations.

3-chloropropanoic acid is subject to various chemical regulations including REACH registration requirements in Europe for commercial use above specified tonnage thresholds. It must be classified and labeled according to CLP regulation standards, though it currently shows no specific GHS classifications in available data. Users must comply with occupational safety regulations, environmental protection laws, and transport regulations for corrosive substances. It is not currently listed as a Substance of Very High Concern (SVHC).

3-chloropropanoic acid is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides reliable supply of quality chemical products to industrial and research customers across Europe. As an established chemical distributor, OYSI ensures proper documentation, regulatory compliance, and technical support for customers requiring 3-chloropropanoic acid for their applications. Contact OYSI directly for availability, specifications, and pricing information tailored to your specific requirements.