3-chloropropanoic acid

3-chloropropanoic acid is an organochlorine compound with the chemical formula C3H5ClO2 and CAS number 107-94-8. This halogenated carboxylic acid features a three-carbon chain with a chlorine atom attached to the third carbon and a carboxyl group. With a molecular weight of 108.52 g/mol, it serves as an important intermediate in organic synthesis and pharmaceutical manufacturing.

3-chloropropanoic acid is typically a colorless to pale yellow liquid or crystalline solid at room temperature. It exhibits good solubility in water and polar organic solvents due to its carboxyl group. The compound has a characteristic acidic odor and demonstrates typical carboxylic acid properties including the ability to form salts with bases and undergo esterification reactions.

3-chloropropanoic acid is primarily used as an intermediate in pharmaceutical synthesis and organic chemistry applications. It serves as a building block for manufacturing various drugs, agrochemicals, and specialty chemicals. The compound is particularly valuable in the production of beta-alanine derivatives and other amino acid analogs used in pharmaceutical research and development.

Safe handling of 3-chloropropanoic acid requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and lab coats. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact, and ensure proper grounding when transferring the material to prevent static discharge.

3-chloropropanoic acid should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers away from strong bases, reducing agents, and metals that may react with the acidic compound. Store in secondary containment to prevent spills and maintain proper inventory management.

In case of skin contact with 3-chloropropanoic acid, immediately flush the affected area with plenty of water for at least 15 minutes and remove contaminated clothing. For eye contact, rinse thoroughly with water for at least 15 minutes. If ingested, rinse mouth with water and seek immediate medical attention. Never induce vomiting unless directed by medical professionals.

3-chloropropanoic acid waste must be disposed of according to local and national hazardous waste regulations. Contact licensed waste disposal companies for proper treatment and disposal. Small quantities may be neutralized carefully with appropriate bases under controlled conditions before disposal, but this should only be done by trained personnel following established protocols.

3-chloropropanoic acid is classified under ADR Class 8 (Corrosive substances), Packing Group II, indicating it requires specific packaging and labeling for transport. Packages must bear appropriate hazard labels and be constructed to ADR specifications. Transportation should comply with dangerous goods regulations including proper documentation and driver certification requirements.

3-chloropropanoic acid is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification rules. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with workplace safety regulations, environmental protection laws, and proper classification and labeling requirements according to applicable jurisdictions.

3-chloropropanoic acid is available through OYSI, a trusted European distributor of specialty chemicals and pharmaceutical intermediates. OYSI provides reliable supply chains across Europe with proper documentation and regulatory compliance. Contact OYSI directly for availability, specifications, and pricing information to meet your specific application requirements.