3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is an organic compound with the molecular formula C19H15ClO4 and CAS number 81-82-3. This chlorinated chromen-2-one derivative has a molecular weight of 342.8 g/mol and belongs to the coumarin family. The compound contains a 4-chlorophenyl group and a hydroxychromen-2-one core structure, making it a complex aromatic molecule with potential biological activity.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is a solid organic compound at room temperature with a molecular weight of 342.8 g/mol. The presence of chlorine, hydroxyl, and carbonyl functional groups influences its polarity and solubility characteristics. As an aromatic compound with both hydrophobic and hydrophilic regions, it likely exhibits moderate solubility in organic solvents and limited water solubility.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is primarily used as an intermediate in pharmaceutical and chemical synthesis. Its chromen-2-one structure makes it valuable for developing compounds with potential biological activities. The molecule serves as a building block in organic synthesis, particularly in the production of more complex pharmaceutical intermediates and research chemicals for various industrial applications.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one requires careful handling due to its STOT RE 2 classification. Wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to minimize exposure. Avoid inhalation, skin contact, and ingestion. Follow proper hygiene practices and wash hands thoroughly after handling.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly closed and properly labeled. Store separately from incompatible materials such as strong oxidizing agents. Maintain storage temperature below 25°C when possible and ensure proper secondary containment to prevent environmental release.

In case of skin contact with 3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one, immediately wash with soap and plenty of water for at least 15 minutes. For eye contact, rinse thoroughly with water for 15 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms persist.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one must be disposed of according to local and national hazardous waste regulations. Contact licensed waste disposal companies for proper treatment and disposal. Due to its Aquatic Chronic 3 classification, prevent release to the environment. Incineration at authorized facilities is typically the preferred disposal method for organic compounds, following all applicable environmental protection guidelines.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is classified as ADR Class 6.1 (toxic substances), Packing Group III. Transport requires appropriate UN-specification packaging and proper shipping documentation. Vehicles must display relevant hazard placards and carry emergency response information. Drivers need ADR certification for dangerous goods transport. Ensure packages are properly labeled, marked, and secured during transportation according to international dangerous goods regulations.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is subject to REACH regulation in Europe and requires registration for import/manufacture above one tonne per year. The compound is not currently listed as an SVHC (Substance of Very High Concern). CLP classification requires appropriate labeling with GHS08 pictogram and 'Warning' signal word. Additional national regulations may apply depending on intended use and quantities handled.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides reliable supply with proper documentation, safety data sheets, and regulatory compliance support. Contact OYSI directly for availability, packaging options, and technical support. Ensure your supplier meets all REACH registration requirements and provides appropriate quality certificates for your intended application.