3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is an organic compound with the molecular formula C19H15ClO4 and CAS number 81-82-3. This chlorinated chromen-2-one derivative has a molecular weight of 342.8 g/mol and contains a 4-chlorophenyl group attached to an oxobutyl chain. The compound features a hydroxylated coumarin backbone, making it part of the chromenone family of organic molecules with potential pharmaceutical or industrial applications.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is a solid organic compound at room temperature with a molecular weight of 342.8 g/mol. The presence of the chlorophenyl group and hydroxyl functionality suggests limited water solubility but good solubility in organic solvents. The compound's chromenone structure typically exhibits crystalline properties, and the chlorine substitution may influence its melting point and stability characteristics compared to non-halogenated analogs.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is primarily used as an intermediate in pharmaceutical synthesis and chemical research applications. Its chromenone structure makes it valuable for developing anticoagulant compounds or other bioactive molecules. The compound may also serve as a building block in organic synthesis, particularly in the development of medicinal chemistry compounds or as a research standard in analytical laboratories studying coumarin derivatives.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one requires careful handling due to its STOT RE 2 classification indicating potential organ toxicity with repeated exposure. Wear appropriate personal protective equipment including safety glasses, chemical-resistant gloves, and lab coats. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid skin and eye contact, and ensure proper hygiene practices including thorough handwashing after handling.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers upright and properly labeled with hazard information. Store away from incompatible materials such as strong oxidizing agents and bases. Maintain storage temperatures according to supplier specifications and ensure adequate segregation from food, feed, and consumables to prevent cross-contamination.

In case of skin contact with 3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, rinse thoroughly with clean water for 15 minutes while keeping eyelids open. If inhaled, move the person to fresh air and seek medical attention if respiratory irritation occurs. Remove contaminated clothing and seek medical advice if symptoms persist or worsen.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one must be disposed of according to local and national hazardous waste regulations. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Do not discharge into drains, waterways, or soil due to its Aquatic Chronic 3 classification. Contaminated packaging should also be treated as hazardous waste. Maintain proper documentation of disposal activities and follow your facility's chemical waste management procedures.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is classified as ADR Class 6.1 (toxic substances), Packing Group III for transportation. Packages must comply with appropriate UN specifications and bear proper hazard labels and markings. Use authorized carriers experienced in handling toxic materials and ensure proper shipping documentation including safety data sheets. Packages should be secured to prevent damage during transit and segregated according to dangerous goods regulations.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is subject to REACH regulation for registration and safety assessment in the European Union. The compound is classified under CLP regulation with STOT RE 2 and Aquatic Chronic 3 hazard classifications, requiring appropriate labeling with GHS08 pictogram and 'Warning' signal word. It is not currently listed as a Substance of Very High Concern (SVHC), but users must comply with occupational exposure limits and environmental protection requirements.

3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one is available through OYSI, a European distributor of specialty chemicals. OYSI provides this compound to pharmaceutical, research, and industrial customers across Europe with proper documentation including certificates of analysis and safety data sheets. Contact OYSI's technical sales team for availability, packaging options, and regulatory compliance documentation to ensure the product meets your specific application requirements and quality standards.