2,4,6-trichloro-1,3,5-triazine

C3Cl3N3

CAS108-77-0
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
108-77-0
EC Number
203-614-9
UN Number
2670
Index Number
613-009-00-5
PubChem CID
7954

Physical-chemical properties

Molecular Formula
C3Cl3N3
Molar Mass
184.41 g/mol
IUPAC Name
2,4,6-trichloro-1,3,5-triazine

Chemical Identifiers

InChI
InChI=1S/C3Cl3N3/c4-1-7-2(5)9-3(6)8-1
InChI Key
MGNCLNQXLYJVJD-UHFFFAOYSA-N

Overview

2,4,6-trichloro-1,3,5-triazine (CAS 108-77-0) is a highly reactive chlorinated triazine compound with strong electrophilic properties and significant industrial versatility. This heterocyclic organic compound, commonly known as cyanuric chloride, represents one of the most important building blocks in organic synthesis and industrial chemistry. With its molecular formula C3Cl3N3 and molecular weight of 184.41 g/mol, this white crystalline substance exhibits exceptional reactivity due to the presence of three chlorine atoms attached to the triazine ring. The compound's high electrophilic character makes it particularly valuable as an intermediate in chemical manufacturing processes. From a safety perspective, 2,4,6-trichloro-1,3,5-triazine requires careful handling protocols. Classified under multiple hazard categories including Acute Tox. 2, Skin Corr. 1B, and Skin Sens. 1, the substance carries a "Danger" signal word and displays GHS06 and GHS05 pictograms. Its classification as ADR Class 8 reflects its corrosive nature, necessitating appropriate storage and transportation measures. The compound's reactivity profile differs significantly from other halogenated compounds such as tribromoborane, which exhibits similar electrophilic behavior but with different selectivity patterns. Industrial applications of this triazine derivative span multiple sectors, including the production of reactive dyes where it serves as a key intermediate for textile coloration processes. Additionally, it plays a crucial role in pharmaceutical synthesis as a building block for various active pharmaceutical ingredients, and functions as an important reagent in agrochemical manufacturing for herbicide and pesticide production. OYSI maintains reliable supply chains for 2,4,6-trichloro-1,3,5-triazine to support diverse industrial requirements across European markets.

Safety & Classification

Danger
Classification:

Acute Tox. 2 *; Acute Tox. 4 *; Skin Corr. 1B; Skin Sens. 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H330

Fatal if inhaled.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

H317

May cause an allergic skin reaction.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2670
ADR Class8
Packing GroupII
Tunnel CodeE
Proper Shipping NameCyanurchlorid, geschmolzen
Marine PollutantNo

Frequently Asked Questions

What is 2,4,6-trichloro-1,3,5-triazine?

2,4,6-trichloro-1,3,5-triazine is a highly reactive chlorinated organic compound with the molecular formula C3Cl3N3 and CAS number 108-77-0. This triazine derivative has a molecular weight of 184.41 g/mol and serves as an important intermediate in chemical synthesis. It belongs to the family of s-triazines and is characterized by three chlorine atoms attached to a six-membered heterocyclic ring containing alternating carbon and nitrogen atoms.

What are the physicochemical properties of 2,4,6-trichloro-1,3,5-triazine?

2,4,6-trichloro-1,3,5-triazine is a white to off-white crystalline solid at room temperature with a characteristic pungent odor. It has limited solubility in water but dissolves well in organic solvents such as acetone, benzene, and chloroform. The compound is highly reactive due to the presence of three activated chlorine atoms, making it susceptible to nucleophilic substitution reactions. It exhibits good thermal stability under normal storage conditions.

What is 2,4,6-trichloro-1,3,5-triazine used for?

2,4,6-trichloro-1,3,5-triazine is primarily used as an intermediate in the synthesis of herbicides, particularly atrazine and other triazine-based pesticides. It serves as a key building block in pharmaceutical manufacturing, dye production, and polymer chemistry. The compound is also utilized in the manufacture of optical brightening agents, reactive dyes for textiles, and various specialty chemicals. Its high reactivity makes it valuable for introducing triazine moieties into complex molecular structures.

How to handle 2,4,6-trichloro-1,3,5-triazine safely?

2,4,6-trichloro-1,3,5-triazine must be handled with extreme caution due to its acute toxicity and corrosive properties. Essential protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Work should be conducted in a fume hood to prevent inhalation exposure. Avoid skin and eye contact completely, as the substance can cause severe burns and sensitization. Personnel should be trained in emergency procedures and have immediate access to eyewash stations and safety showers.

How to store 2,4,6-trichloro-1,3,5-triazine correctly?

2,4,6-trichloro-1,3,5-triazine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers in secondary containment to prevent spills and maintain temperatures below 25°C for optimal stability. Store away from incompatible materials such as strong bases, alcohols, and amines which can react violently. Ensure proper labeling and restrict access to authorized personnel only. Regular inspection of container integrity is essential.

What to do in case of contact with 2,4,6-trichloro-1,3,5-triazine?

Immediate action is critical upon contact with 2,4,6-trichloro-1,3,5-triazine due to its corrosive nature. For skin contact, remove contaminated clothing immediately and flush affected area with copious amounts of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention promptly in all cases of exposure, and bring the safety data sheet to medical personnel.

How to dispose of 2,4,6-trichloro-1,3,5-triazine appropriately?

2,4,6-trichloro-1,3,5-triazine must be disposed of as hazardous waste through licensed waste management companies in compliance with local and European regulations. The material cannot be discharged to sewers or waterways due to its toxicity and environmental persistence. Contaminated packaging should also be treated as hazardous waste. Disposal methods typically involve high-temperature incineration at authorized facilities. Maintain detailed records of all disposal activities and ensure proper waste classification codes are used.

How to transport 2,4,6-trichloro-1,3,5-triazine?

2,4,6-trichloro-1,3,5-triazine is classified as dangerous goods under ADR regulations as Class 8 (corrosive substances), Packing Group II. Transport requires appropriate UN-approved packaging, proper labeling with GHS06 and GHS05 pictograms, and accompanying transport documents including safety data sheets. Vehicles must carry appropriate emergency equipment and drivers need hazardous materials training. Shipments must comply with quantity limitations and routing restrictions as specified in ADR regulations for corrosive materials.

Is 2,4,6-trichloro-1,3,5-triazine subject to specific regulations?

2,4,6-trichloro-1,3,5-triazine is regulated under multiple European frameworks including REACH registration requirements and CLP classification as Acute Tox. 2/4, Skin Corr. 1B, and Skin Sens. 1. While not currently listed as an SVHC substance, it requires proper hazard communication through safety data sheets and labeling. Users must comply with occupational exposure limits, environmental discharge restrictions, and may need permits for industrial use. Import/export may require additional notifications depending on quantities and end-use applications.

Where to buy 2,4,6-trichloro-1,3,5-triazine in Europe?

2,4,6-trichloro-1,3,5-triazine is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. OYSI provides comprehensive regulatory support, technical documentation, and ensures full compliance with European chemical regulations. As an established chemical distributor, OYSI offers reliable supply chains, proper packaging, and expert guidance on handling requirements. Contact OYSI directly for availability, technical specifications, and regulatory compliance support for your specific application needs.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.