2,2,3-trifluoro-3-(trifluoromethyl)oxirane

C3F6O

CAS428-59-1

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Identification

CAS Number
428-59-1
EC Number
207-050-4
UN Number
3163
PubChem CID
9883

Physical-chemical properties

Molecular Formula
C3F6O
Molar Mass
166.02 g/mol
IUPAC Name
2,2,3-trifluoro-3-(trifluoromethyl)oxirane

Chemical Identifiers

InChI
InChI=1S/C3F6O/c4-1(2(5,6)7)3(8,9)10-1
InChI Key
PGFXOWRDDHCDTE-UHFFFAOYSA-N

Overview

2,2,3-trifluoro-3-(trifluoromethyl)oxirane (CAS 428-59-1) is a highly fluorinated epoxide compound with exceptional chemical stability and unique reactivity properties. This specialized fluorinated oxirane represents a distinctive class of organofluorine compounds characterized by its three-membered epoxide ring bearing multiple fluorine substituents. With the molecular formula C3F6O and a molecular weight of 166.02 g/mol, this compound exhibits remarkable chemical properties that distinguish it from conventional epoxides. The extensive fluorination imparts exceptional thermal stability, chemical inertness, and unique electronic characteristics that make it valuable for specialized industrial applications. The compound's structure features both difluoro substitution at the 2-position and a trifluoromethyl group at the 3-position of the oxirane ring, creating a highly electronegative environment that significantly influences its reactivity patterns. Unlike simpler compounds such as nitrous oxide, this fluorinated epoxide maintains its structural integrity under demanding conditions while offering selective reactivity through its strained ring system. From a safety perspective, 2,2,3-trifluoro-3-(trifluoromethyl)oxirane is classified under ADR Class 2, indicating its gaseous nature under standard conditions. The absence of specific GHS pictograms suggests relatively manageable handling requirements when proper protocols are followed, though standard precautions for fluorinated compounds should always be observed. Industrial applications primarily include use as a specialty fluorinating agent in pharmaceutical synthesis, as an intermediate in the production of high-performance fluoropolymers, and in the development of advanced materials requiring exceptional chemical resistance. The compound also finds application in specialized research contexts where its unique combination of epoxide reactivity and fluorine chemistry is advantageous. OYSI maintains reliable supplies of 2,2,3-trifluoro-3-(trifluoromethyl)oxirane to support European industrial and research requirements.

Safety & Classification

No Hazard Classification

This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.

Transport (ADR)

UN Number3163
ADR Class2
Packing Group
Tunnel CodeC/E
Proper Shipping NameHexafluorpropenoxid, unter Druck verflüssigt
Marine PollutantNo

Frequently Asked Questions

What is 2,2,3-trifluoro-3-(trifluoromethyl)oxirane?

2,2,3-trifluoro-3-(trifluoromethyl)oxirane is a highly fluorinated epoxide compound with the molecular formula C3F6O and CAS number 428-59-1. This specialized chemical features a three-membered oxirane ring structure with extensive fluorine substitution, giving it unique properties. With a molecular weight of 166.02 g/mol, it belongs to the family of fluorinated organic compounds used primarily in advanced chemical synthesis and specialized industrial applications requiring high chemical resistance and stability.

What are the physicochemical properties of 2,2,3-trifluoro-3-(trifluoromethyl)oxirane?

2,2,3-trifluoro-3-(trifluoromethyl)oxirane is a volatile liquid at room temperature due to its low molecular weight and fluorinated structure. The extensive fluorine substitution imparts high chemical stability, low surface tension, and excellent thermal resistance. Like most fluorinated compounds, it exhibits low solubility in water but good solubility in organic solvents. The compound typically appears as a colorless liquid with minimal odor, and its fluorinated nature gives it unique dielectric properties.

What is 2,2,3-trifluoro-3-(trifluoromethyl)oxirane used for?

2,2,3-trifluoro-3-(trifluoromethyl)oxirane serves as a valuable building block in fluorinated polymer synthesis and specialty chemical manufacturing. Its reactive epoxide group allows for ring-opening reactions to create fluorinated intermediates for pharmaceutical, agrochemical, and materials science applications. The compound is particularly useful in developing high-performance materials requiring chemical inertness, thermal stability, and low surface energy properties, such as specialized coatings, surfactants, and advanced polymer systems.

How to handle 2,2,3-trifluoro-3-(trifluoromethyl)oxirane safely?

2,2,3-trifluoro-3-(trifluoromethyl)oxirane should be handled with standard laboratory safety precautions including chemical-resistant gloves, safety goggles, and adequate ventilation. Work in a well-ventilated area or fume hood to prevent vapor accumulation. Use appropriate personal protective equipment when transferring or processing the material. Avoid contact with skin and eyes, and prevent inhalation of vapors. Ensure proper grounding when handling to prevent static electricity buildup, and keep containers tightly sealed when not in use.

How to store 2,2,3-trifluoro-3-(trifluoromethyl)oxirane correctly?

2,2,3-trifluoro-3-(trifluoromethyl)oxirane should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers upright and properly labeled in designated chemical storage areas. Avoid storage near strong bases or nucleophiles that could react with the epoxide group. Use appropriate secondary containment and ensure storage areas have adequate temperature control. Regularly inspect containers for signs of deterioration or leakage, and maintain proper inventory management.

What to do in case of contact with 2,2,3-trifluoro-3-(trifluoromethyl)oxirane?

In case of skin contact with 2,2,3-trifluoro-3-(trifluoromethyl)oxirane, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Remove the person from exposure and ensure they rest in a comfortable position. Seek medical attention if irritation persists or if significant exposure has occurred.

How to dispose of 2,2,3-trifluoro-3-(trifluoromethyl)oxirane properly?

2,2,3-trifluoro-3-(trifluoromethyl)oxirane must be disposed of according to local, national, and EU waste regulations as a chemical waste. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Do not pour down drains or release into the environment. Collect waste in appropriate containers, properly labeled with contents and hazards. Consider waste minimization through process optimization and recycling where feasible. Maintain detailed waste disposal records as required by environmental regulations.

How to transport 2,2,3-trifluoro-3-(trifluoromethyl)oxirane?

2,2,3-trifluoro-3-(trifluoromethyl)oxirane is classified under ADR Class 2 for transportation, indicating it falls under gases or gas-related materials. Proper packaging must comply with UN specifications and ADR requirements for this classification. Use appropriate shipping containers that meet regulatory standards, ensure proper labeling and documentation, and work with carriers experienced in chemical transport. Verify that all transport documentation includes correct identification numbers, proper shipping names, and required hazard labels according to ADR regulations.

Is 2,2,3-trifluoro-3-(trifluoromethyl)oxirane subject to specific regulations?

2,2,3-trifluoro-3-(trifluoromethyl)oxirane is subject to standard EU chemical regulations including REACH registration requirements and CLP classification obligations. The compound is not currently listed as an SVHC (Substance of Very High Concern) under REACH. Standard chemical safety data sheet requirements apply, and users must comply with workplace exposure regulations. Import/export may require appropriate documentation, and any commercial use should ensure compliance with relevant industry-specific regulations and customer requirements for chemical substances.

Where to buy 2,2,3-trifluoro-3-(trifluoromethyl)oxirane in Europe?

2,2,3-trifluoro-3-(trifluoromethyl)oxirane is available through OYSI, a trusted European distributor of specialty chemicals serving industrial and research customers across the continent. OYSI provides reliable supply chain management and technical support for fluorinated compounds and specialty chemicals. Contact OYSI directly for availability, specifications, and delivery options to your location. Their experienced team can assist with product selection, regulatory compliance, and technical applications to meet your specific requirements for this specialized fluorinated epoxide compound.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.