2-(phosphonomethylamino)acetic acid

2-(phosphonomethylamino)acetic acid is an organophosphorus compound with the molecular formula C3H8NO5P and CAS number 1071-83-6. This chemical features both phosphonic acid and amino acid functional groups, making it a phosphono-amino acid derivative. With a molecular weight of 169.07 g/mol, it belongs to a class of compounds known for their chelating properties and biological activity. The substance is classified as hazardous due to its potential for causing serious eye damage and chronic aquatic toxicity.

2-(phosphonomethylamino)acetic acid typically appears as a white to off-white crystalline solid at room temperature. The compound is highly soluble in water due to its polar phosphonic acid and carboxylic acid groups. It exhibits acidic properties with multiple ionizable protons from both the phosphonic and carboxylic acid functionalities. The substance is stable under normal conditions but should be protected from moisture and extreme temperatures to maintain its integrity and prevent degradation.

2-(phosphonomethylamino)acetic acid serves primarily as a chelating agent and intermediate in chemical synthesis. Its dual acid functionality makes it effective for metal ion complexation in industrial processes, water treatment applications, and analytical chemistry. The compound is also utilized in pharmaceutical research and development, particularly in the synthesis of organophosphorus-based drugs. Additionally, it finds applications in agricultural chemistry and as a building block for specialized chemical formulations requiring phosphono-amino acid structures.

2-(phosphonomethylamino)acetic acid requires careful handling due to its Eye Dam. 1 classification. Always wear safety goggles, chemical-resistant gloves, and protective clothing when handling this substance. Work in a well-ventilated area or under a fume hood to prevent inhalation exposure. Avoid direct contact with skin and eyes, and never eat, drink, or smoke in work areas. Use appropriate dispensing equipment to minimize dust generation and potential exposure. Ensure emergency eyewash stations and safety showers are readily accessible.

2-(phosphonomethylamino)acetic acid should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep containers upright and properly labeled according to GHS requirements, displaying the appropriate danger pictogrammes (GHS05, GHS09). Store separately from incompatible materials such as strong bases and oxidizing agents. Ensure storage areas have appropriate spill containment measures and are accessible only to trained personnel wearing proper protective equipment.

Eye contact with 2-(phosphonomethylamino)acetic acid requires immediate action due to its severe eye damage potential. Flush eyes immediately with plenty of clean water for at least 15 minutes, holding eyelids open to ensure thorough rinsing. Remove contact lenses if present and easily removable. For skin contact, wash affected area thoroughly with soap and water. In case of inhalation, move the person to fresh air immediately. Seek immediate medical attention for all exposure incidents, particularly eye contact, and provide the safety data sheet to medical personnel.

2-(phosphonomethylamino)acetic acid must be disposed of according to local and national hazardous waste regulations due to its classification as dangerous goods. Do not discharge into drains, waterways, or soil due to its Aquatic Chronic 2 classification. Collect waste in appropriate labeled containers and arrange disposal through licensed hazardous waste contractors. Consider neutralization or treatment methods where permitted by regulations. Maintain proper documentation of all disposal activities and ensure compliance with REACH and local environmental protection requirements.

2-(phosphonomethylamino)acetic acid is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. Use appropriate UN-specification packaging that meets the requirements for Class 9 materials. Ensure proper labeling with the correct UN number, proper shipping name, and hazard labels. Transport documents must include all required information according to ADR regulations. Drivers must possess appropriate training certificates, and vehicles should carry suitable emergency equipment for Class 9 materials.

2-(phosphonomethylamino)acetic acid is subject to REACH regulation and must comply with CLP classification requirements in Europe. The substance is classified with hazard pictogrammes GHS05 and GHS09, requiring appropriate labeling and safety data sheets. It is not currently listed as a Substance of Very High Concern (SVHC). Users must ensure compliance with occupational health and safety regulations, environmental protection laws, and proper notification procedures under REACH. Industrial users may need to prepare chemical safety reports depending on usage volumes and applications.

2-(phosphonomethylamino)acetic acid is available through OYSI, a trusted European distributor of specialty chemicals. OYSI provides high-quality chemical products with full regulatory compliance including proper CLP labeling, safety data sheets, and REACH documentation. As a specialized chemical distributor, OYSI ensures reliable supply chains and technical support for industrial customers across Europe. Contact OYSI directly for product specifications, availability, and technical assistance regarding 2-(phosphonomethylamino)acetic acid for your specific applications and requirements.