2-methyloxirane
C3H6O
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Identification
- CAS Number
- 75-56-9
- EC Number
- 200-879-2
- UN Number
- 1280
- Index Number
- 603-055-00-4
- PubChem CID
- 6378
Physical-chemical properties
- Molecular Formula
- C3H6O
- Molar Mass
- 58.08 g/mol
- IUPAC Name
- 2-methyloxirane
Chemical Identifiers
- InChI
- InChI=1S/C3H6O/c1-3-2-4-3/h3H,2H2,1H3
- InChI Key
- GOOHAUXETOMSMM-UHFFFAOYSA-N
Overview
2-methyloxirane (CAS 75-56-9) is a highly reactive epoxide compound with significant industrial importance and notable safety considerations due to its flammable and potentially carcinogenic properties. This three-membered cyclic ether, also known by its IUPAC designation 2-methyloxirane, represents a critical intermediate in numerous chemical manufacturing processes. With the molecular formula C3H6O and a molecular weight of 58.08 g/mol, this colorless liquid exhibits exceptional reactivity due to the inherent ring strain characteristic of epoxide compounds. The European chemical classification system assigns this substance multiple hazard categories, including Flammable Liquid Category 1, reflecting its extremely low flash point, and Carcinogen Category 1B, indicating serious long-term health concerns requiring stringent handling protocols. The compound's high reactivity makes it particularly valuable in polymer chemistry and organic synthesis applications. Its ability to undergo ring-opening reactions with various nucleophiles positions it as a versatile building block for producing specialty chemicals, pharmaceutical intermediates, and advanced materials. In industrial settings, 2-methyloxirane serves as a key component in the manufacture of polyurethane foams, surface coatings, and adhesive formulations. The chemical industry also utilizes this epoxide in producing propylene glycol derivatives and as a sterilizing agent for heat-sensitive medical equipment. Like other reactive intermediates such as prop-2-enenitrile, 2-methyloxirane requires specialized storage conditions and expert handling due to its combination of high reactivity and safety hazards. Transportation falls under ADR Class 3 regulations, necessitating compliance with stringent logistics protocols. OYSI maintains technical-grade 2-methyloxirane availability for qualified industrial customers throughout Europe, ensuring proper regulatory compliance and safety documentation.
Safety & Classification
Flam. Liq. 1; Carc. 1B; Muta. 1B; Acute Tox. 3; Acute Tox. 3; Acute Tox. 4; STOT SE 3; Eye Irrit. 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1280 |
| ADR Class | 3 |
| Packing Group | I |
| Tunnel Code | D/E |
| Proper Shipping Name | Propylenoxid |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-methyloxirane?
2-methyloxirane is an organic chemical compound with the molecular formula C3H6O and CAS number 75-56-9. It belongs to the epoxide family, characterized by a three-membered ring containing an oxygen atom. With a molecular weight of 58.08 g/mol, this substance is classified as highly hazardous due to its flammable, carcinogenic, and mutagenic properties. It requires careful handling and is subject to strict safety regulations in industrial applications.
What are the physicochemical properties of 2-methyloxirane?
2-methyloxirane is a highly volatile liquid at room temperature with a characteristic ether-like odor. As an epoxide, it exhibits high reactivity due to the strain in its three-membered ring structure. The compound has a low boiling point and is highly flammable, classified as Flammable Liquid Category 1. It is soluble in most organic solvents and shows limited solubility in water, making it useful in various chemical synthesis applications.
What is 2-methyloxirane used for?
2-methyloxirane serves primarily as an intermediate in chemical synthesis and polymer production. It is widely used in the manufacture of polyurethane foams, surfactants, and specialty chemicals. The compound acts as a reactive building block for producing various derivatives including glycol ethers and pharmaceuticals. Its epoxide functionality makes it valuable for ring-opening reactions in organic synthesis, contributing to the production of coatings, adhesives, and other industrial materials.
How to handle 2-methyloxirane safely?
2-methyloxirane requires strict safety measures due to its multiple hazard classifications. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Eliminate all ignition sources as the substance is extremely flammable. Regular health monitoring is essential due to its carcinogenic and mutagenic properties. Emergency equipment should be readily available.
How to store 2-methyloxirane correctly?
2-methyloxirane must be stored in cool, dry, well-ventilated areas away from heat sources, sparks, and open flames. Use only approved containers designed for flammable liquids, preferably under inert atmosphere to prevent degradation. Storage temperature should be kept low to minimize vapor pressure and decomposition risk. Keep away from incompatible materials such as acids, bases, and oxidizing agents. Implement proper grounding and bonding procedures to prevent static electricity buildup.
What to do in case of contact with 2-methyloxirane?
Immediate action is critical upon contact with 2-methyloxirane. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. In case of eye contact, flush immediately with clean water and seek medical attention. If inhaled, move to fresh air and monitor breathing. For ingestion, do not induce vomiting and seek immediate medical care. Always consult a poison control center or medical professional promptly due to the substance's toxic properties.
How to dispose of 2-methyloxirane properly?
2-methyloxirane disposal must comply with local and international hazardous waste regulations due to its multiple classifications. The substance cannot be disposed of through regular waste streams and requires specialized hazardous waste treatment facilities. Incineration at approved high-temperature facilities is typically the preferred method. Small quantities may require neutralization or chemical treatment before disposal. Always consult with certified waste management companies and obtain proper waste codes for documentation and tracking purposes.
How to transport 2-methyloxirane?
2-methyloxirane is classified under ADR transport regulations as Class 3 (Flammable Liquids), Packing Group I, indicating the highest level of danger. Transportation requires UN-approved packaging and proper hazard labeling including flammable liquid markings. Vehicles must carry appropriate emergency equipment and documentation. Drivers need specialized training for dangerous goods transport. The substance must be segregated from incompatible materials and secured to prevent movement during transit. Emergency response information must accompany shipments.
Is 2-methyloxirane subject to specific regulations?
2-methyloxirane is subject to extensive regulatory oversight under multiple frameworks. Under REACH regulation, it requires registration and safety data sheets for commercial use. CLP classification mandates specific hazard communication including 'Danger' signal word and appropriate pictograms (GHS02, GHS06, GHS08). Due to its carcinogenic and mutagenic properties, workplace exposure limits are strictly regulated. Additional restrictions may apply for certain uses, and regular monitoring of occupational exposure is typically required in industrial settings.
Where to buy 2-methyloxirane in Europe?
2-methyloxirane is available through specialized chemical distributors in Europe, including OYSI, which supplies industrial chemicals to the European market. Due to its hazardous classification, purchases typically require proper business credentials, safety documentation, and end-use declarations. Suppliers must provide complete safety data sheets and ensure compliance with transport regulations. Professional chemical distributors like OYSI can assist with regulatory requirements and provide technical support for safe handling and application guidance.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.