2-methyloxirane

C3H6O

CAS75-56-9
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
75-56-9
EC Number
200-879-2
UN Number
1280
Index Number
603-055-00-4
PubChem CID
6378

Physical-chemical properties

Molecular Formula
C3H6O
Molar Mass
58.08 g/mol
IUPAC Name
2-methyloxirane

Chemical Identifiers

InChI
InChI=1S/C3H6O/c1-3-2-4-3/h3H,2H2,1H3
InChI Key
GOOHAUXETOMSMM-UHFFFAOYSA-N

Overview

2-methyloxirane (CAS 75-56-9) is a highly reactive three-membered cyclic ether with significant industrial importance and notable safety considerations due to its flammable and carcinogenic properties. Also known by its IUPAC name 2-methyloxirane, this organic compound belongs to the epoxide family and serves as a crucial intermediate in various chemical manufacturing processes. With the molecular formula C3H6O and a molecular weight of 58.08 g/mol, this colorless liquid exhibits exceptional reactivity due to the ring strain inherent in its three-membered oxirane structure. The presence of the methyl substituent distinguishes it from simpler epoxides and influences both its reactivity patterns and industrial applications. The compound presents significant safety challenges, classified under multiple hazard categories including Flam. Liq. 1, Carc. 1B, and Muta. 1B, requiring strict handling protocols and specialized storage conditions. Its classification under ADR Class 3 reflects its highly flammable nature, while the GHS pictogrammes GHS02, GHS08, and GHS06 indicate fire, health, and toxicity hazards respectively. These properties necessitate comprehensive risk management strategies in industrial settings. In industrial applications, 2-methyloxirane serves primarily as a chemical intermediate in polymer synthesis and pharmaceutical manufacturing. Its high reactivity makes it valuable for producing specialized polymers and as a building block in organic synthesis pathways. The compound shares certain applications with related substances such as 2-ethoxyethanol in solvent systems, though its unique reactivity profile sets it apart from other industrial chemicals like prop-2-enenitrile. OYSI provides 2-methyloxirane to qualified industrial customers with comprehensive technical support and regulatory documentation to ensure safe handling and compliance with European chemical regulations.

Safety & Classification

Danger
Classification:

Flam. Liq. 1; Carc. 1B; Muta. 1B; Acute Tox. 3; Acute Tox. 3; Acute Tox. 4; STOT SE 3; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H224

Extremely flammable liquid and vapour.

H350

May cause cancer.

H340

May cause genetic defects.

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H302

Harmful if swallowed.

H335

May cause respiratory irritation.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1280
ADR Class3
Packing GroupI
Tunnel CodeD/E
Proper Shipping NamePropylenoxid
Marine PollutantNo

Frequently Asked Questions

What is 2-methyloxirane?

2-methyloxirane is an organic chemical compound with the molecular formula C3H6O and CAS number 75-56-9. It belongs to the epoxide family, characterized by a three-membered ring containing an oxygen atom. With a molecular weight of 58.08 g/mol, this substance is classified as highly hazardous due to its flammable, carcinogenic, and mutagenic properties. It requires careful handling under controlled conditions due to its significant health and safety risks.

What are the physicochemical properties of 2-methyloxirane?

2-methyloxirane is a colorless liquid at room temperature with a characteristic ether-like odor. As an epoxide, it exhibits high reactivity due to ring strain in its three-membered cyclic structure. The compound has a low boiling point and high vapor pressure, making it highly volatile. It is miscible with most organic solvents and shows limited solubility in water. Its high flammability classification (Flam. Liq. 1) indicates extremely low flash point and easy ignition.

What is 2-methyloxirane used for?

2-methyloxirane serves primarily as an intermediate in chemical synthesis and polymer production. It is used in the manufacture of polyols, surfactants, and specialty chemicals through ring-opening reactions. The compound finds applications in producing glycol ethers, pharmaceutical intermediates, and industrial solvents. Due to its high reactivity, it is valuable in creating branched polymer structures and as a building block for complex organic molecules in fine chemical manufacturing.

How to handle 2-methyloxirane safely?

Safe handling of 2-methyloxirane requires comprehensive protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods due to its toxic vapors and carcinogenic properties. Avoid all ignition sources as it is extremely flammable (Class 1). Personnel should be trained on emergency procedures, and exposure monitoring is essential. Minimize skin and eye contact, and ensure immediate access to emergency eyewash and shower facilities.

How to store 2-methyloxirane correctly?

2-methyloxirane must be stored in tightly sealed containers in cool, dry, and well-ventilated areas away from heat sources and ignition. Storage requires temperature control below 25°C and protection from direct sunlight. The substance should be kept separate from strong acids, bases, and oxidizing agents due to potential violent reactions. Use only approved containers resistant to chemical attack, and implement proper grounding procedures to prevent static electricity buildup during handling.

What to do in case of contact with 2-methyloxirane?

Immediate action is required for any contact with 2-methyloxirane. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye exposure, flush immediately with clean water for 15-20 minutes while keeping eyelids open. If inhaled, move victim to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Contact poison control center and provide safety data sheet to medical personnel.

How to dispose of 2-methyloxirane appropriately?

2-methyloxirane disposal must comply with local and national hazardous waste regulations as it is classified as dangerous waste. The substance cannot be disposed of in regular waste streams due to its carcinogenic and mutagenic properties. Disposal should be performed only by licensed hazardous waste management companies through approved methods such as high-temperature incineration or chemical treatment. Maintain proper documentation and waste manifests as required by environmental regulations.

How to transport 2-methyloxirane?

2-methyloxirane is classified under ADR Class 3 (flammable liquids), Packing Group I, indicating maximum danger level for transport. Transportation requires specialized containers meeting UN specifications and proper hazard labeling with flammable liquid markings. Vehicles must be equipped with appropriate fire extinguishing equipment and drivers need ADR certification. Transport documentation must include proper shipping names, hazard classes, and emergency response information. Temperature control during transport may be necessary to prevent vapor buildup.

Is 2-methyloxirane subject to specific regulations?

2-methyloxirane is subject to extensive regulatory oversight under REACH, CLP, and national chemical legislation due to its carcinogenic (1B) and mutagenic (1B) classification. The substance requires registration under REACH for manufacturing or import above threshold quantities. Workplace exposure limits apply, and users must implement risk management measures. Special authorizations may be required for certain uses, and the substance is subject to strict labeling requirements including danger pictograms GHS02, GHS06, and GHS08.

Where to buy 2-methyloxirane in Europe?

2-methyloxirane is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substance handling. OYSI provides proper documentation, safety data sheets, and regulatory compliance support for this controlled substance. Due to its hazardous classification, purchase requires verification of intended use and compliance with regulatory requirements. Professional customers can contact OYSI for availability, technical specifications, and guidance on safe handling procedures for this specialized chemical intermediate.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.