2-ethoxyethanol

C4H10O2

CAS110-80-5
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
110-80-5
EC Number
203-804-1
UN Number
1171
Index Number
603-012-00-X
PubChem CID
8076

Physical-chemical properties

Molecular Formula
C4H10O2
Molar Mass
90.12 g/mol
IUPAC Name
2-ethoxyethanol

Chemical Identifiers

InChI
InChI=1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3
InChI Key
ZNQVEEAIQZEUHB-UHFFFAOYSA-N

Overview

2-ethoxyethanol (CAS 110-80-5) is a glycol ether solvent with excellent solvency properties and moderate volatility for industrial applications. 2-ethoxyethanol represents a key member of the glycol ether family, widely utilized across various industrial sectors for its unique combination of solvent properties. This colorless liquid, with the molecular formula C4H10O2 and molecular weight of 90.12 g/mol, demonstrates exceptional miscibility with both water and organic solvents, making it particularly valuable in formulation chemistry. The compound's dual ether and alcohol functionality provides superior dissolving capabilities for a broad range of substances, including resins, oils, and various organic compounds. From a safety perspective, 2-ethoxyethanol requires careful handling protocols due to its classification as a reproductive toxicant (Repr. 1B) and acute toxicity concerns (Acute Tox. 3 and 4). The substance carries the "Danger" signal word and displays GHS pictograms for flammability (GHS02), health hazards (GHS08), and acute toxicity (GHS06). As a Class 3 flammable liquid under ADR regulations, proper storage and transportation measures are essential. Unlike some other industrial solvents such as prop-2-enenitrile, 2-ethoxyethanol offers lower volatility while maintaining effective solvency characteristics. Primary industrial applications include its use as a coalescent in water-based paints and coatings, where it enhances film formation and durability. The chemical industry also employs 2-ethoxyethanol in cleaning formulations and as a process solvent in various manufacturing operations. Additionally, it serves as an intermediate in the production of specialized chemicals and pharmaceutical compounds. OYSI maintains reliable supply chains for 2-ethoxyethanol, ensuring consistent availability for European industrial customers requiring this versatile glycol ether solvent.

Safety & Classification

Danger
Classification:

Flam. Liq. 3; Repr. 1B; Acute Tox. 3; Acute Tox. 4

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H331

Toxic if inhaled.

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1171
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameEthylenglycolmonoethylether
Marine PollutantNo

Frequently Asked Questions

What is 2-ethoxyethanol?

2-ethoxyethanol is an organic chemical compound with the molecular formula C4H10O2 and CAS number 110-80-5. It belongs to the glycol ether family and has a molecular weight of 90.12 g/mol. This substance is classified as a flammable liquid with significant health hazards, including reproductive toxicity and acute toxicity. It appears as a colorless liquid with a mild, pleasant odor and is completely miscible with water and most organic solvents.

What are the physicochemical properties of 2-ethoxyethanol?

2-ethoxyethanol is a colorless liquid at room temperature with a characteristic mild, ether-like odor. It has excellent solubility properties, being completely miscible with water, alcohols, and most organic solvents due to its dual hydrophilic and lipophilic nature. The compound has a relatively low vapor pressure and moderate volatility. Its glycol ether structure provides good solvating properties for both polar and non-polar substances, making it effective in various formulations.

What is 2-ethoxyethanol used for?

2-ethoxyethanol is primarily used as a solvent in industrial applications, particularly in coatings, inks, and cleaning formulations. It serves as an excellent solvent for resins, dyes, and various organic compounds due to its dual solubility characteristics. The compound is also utilized in textile processing, leather treatment, and as a component in certain chemical synthesis processes. However, its use has been restricted in consumer products due to its reproductive toxicity classification.

How to handle 2-ethoxyethanol safely?

2-ethoxyethanol requires strict safety measures due to its reproductive toxicity and flammability. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection in poorly ventilated areas. Work in well-ventilated spaces or under fume hoods to minimize inhalation exposure. Avoid skin contact and ensure no ignition sources are present due to its flammable nature. Pregnant women should avoid any exposure to this substance given its Repr. 1B classification.

How to store 2-ethoxyethanol correctly?

2-ethoxyethanol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames due to its flammable classification (Class 3). Keep containers in secondary containment and away from incompatible materials such as strong oxidizing agents. Storage areas should be equipped with appropriate fire suppression systems and maintained below recommended temperature limits. Ensure proper labeling and access restriction to trained personnel only.

What to do in case of contact with 2-ethoxyethanol?

In case of skin contact with 2-ethoxyethanol, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, flush immediately with clean water for at least 15 minutes and seek medical attention. In case of inhalation, move the person to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet for proper medical treatment.

How to dispose of 2-ethoxyethanol appropriately?

2-ethoxyethanol must be disposed of as hazardous waste according to local and European waste regulations. Do not pour down drains or dispose of in regular trash due to its toxicity and environmental impact. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities should be collected in appropriate containers and labeled clearly. Follow national transposition of the Waste Framework Directive and ensure proper waste classification codes are used for disposal documentation.

How to transport 2-ethoxyethanol?

2-ethoxyethanol is classified under ADR as Class 3 (flammable liquids), Packing Group III, requiring specific transport regulations. Packages must be properly labeled with appropriate hazard pictogrammes and shipped in approved containers meeting UN specification standards. Transport vehicles must carry appropriate emergency equipment and documentation. Drivers require ADR training certification for dangerous goods transport. Ensure proper segregation from incompatible materials during transport and follow temperature restrictions if applicable.

Is 2-ethoxyethanol subject to specific regulations?

2-ethoxyethanol is subject to strict European regulations under REACH and CLP due to its reproductive toxicity classification. It requires authorization for certain uses and is restricted in consumer products under REACH Annex XVII. The substance must be properly classified and labeled according to CLP regulation with appropriate hazard statements and precautionary measures. Industrial users must implement risk management measures and may need to notify authorities depending on usage volumes and applications.

Where to buy 2-ethoxyethanol in Europe?

2-ethoxyethanol is available through OYSI, a specialized European distributor of industrial chemicals. OYSI provides this regulated substance to qualified industrial customers with proper documentation and compliance support. As a professional chemical distributor, OYSI ensures full regulatory compliance, proper packaging, and technical support for industrial applications. Contact OYSI directly for availability, specifications, and regulatory documentation required for your specific application and location within Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.