2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide

C9H20NO3PS2

CAS2275-18-5
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
2275-18-5
EC Number
218-893-2
UN Number
2783
Index Number
015-032-00-0
PubChem CID
16774

Physical-chemical properties

Molecular Formula
C9H20NO3PS2
Molar Mass
285.40 g/mol
IUPAC Name
2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide

Chemical Identifiers

InChI
InChI=1S/C9H20NO3PS2/c1-5-12-14(15,13-6-2)16-7-9(11)10-8(3)4/h8H,5-7H2,1-4H3,(H,10,11)
InChI Key
QTXHFDHVLBDJIO-UHFFFAOYSA-N

Overview

2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide (CAS 2275-18-5) is an organophosphorus compound with acute toxicity properties and environmental persistence characteristics. This specialized chemical compound, with the molecular formula C9H20NO3PS2 and molecular weight of 285.4 g/mol, represents a significant organophosphorus derivative used in various industrial applications. The compound features a complex structure combining phosphinothioyl and acetamide functional groups, which contribute to its unique chemical properties and biological activity profile. Its EC number 218-893-2 confirms its registration within European chemical databases, ensuring regulatory compliance for commercial use. The substance exhibits high acute toxicity characteristics, classified as Acute Tox. 1 and Acute Tox. 2 under the CLP Regulation, requiring the "Danger" signal word and GHS06 skull and crossbones pictogram. These safety classifications necessitate stringent handling protocols and proper personal protective equipment during industrial operations. Additionally, its Aquatic Chronic 3 classification indicates potential long-term effects on aquatic environments, requiring careful waste management and disposal procedures. Transportation falls under ADR Class 6.1, designating it as a toxic substance requiring specialized shipping arrangements. Industrial applications typically include use as an intermediate in pharmaceutical synthesis, specialty chemical manufacturing, and research applications requiring organophosphorus compounds. Unlike simpler aromatic compounds such as chloromethylbenzene or N-methylaniline, this molecule's complex phosphorus-sulfur framework provides unique reactivity patterns valuable in specialized synthetic processes. The compound's dual sulfur-phosphorus functionality makes it particularly suitable for applications requiring specific chelating or coordination properties. OYSI maintains reliable supply chains for this technical-grade compound, supporting European industrial customers with consistent quality and regulatory documentation.

Safety & Classification

Danger
Classification:

Acute Tox. 1; Acute Tox. 2 *; Aquatic Chronic 3

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H310

Fatal in contact with skin.

H300

Fatal if swallowed.

H412

Harmful to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Fatal

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2783
ADR Class6.1
Packing GroupI
Tunnel CodeC/E
Proper Shipping NameProthoat (ISO), fest
Marine PollutantNo

Frequently Asked Questions

What is 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide?

2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide is an organophosphorus compound with the molecular formula C9H20NO3PS2 and CAS number 2275-18-5. This chemical substance has a molecular weight of 285.4 g/mol and belongs to the class of phosphorothioate derivatives. It is classified as extremely hazardous due to its acute toxicity properties and requires careful handling under strict safety protocols in professional environments.

What are the physicochemical properties of 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide?

2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide is an organophosphorus compound with a molecular weight of 285.4 g/mol and molecular formula C9H20NO3PS2. The substance contains phosphorus, sulfur, nitrogen and oxygen atoms in its structure, giving it specific chemical reactivity. As a phosphorothioate derivative, it typically exhibits moderate stability under normal conditions but may be sensitive to hydrolysis and oxidation reactions.

What is 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide used for?

2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide is primarily used in specialized industrial applications requiring organophosphorus chemistry. Its specific molecular structure makes it valuable in research and development processes, particularly in pharmaceutical intermediates and chemical synthesis. Due to its high acute toxicity classification, its use is restricted to professional environments with appropriate safety measures and trained personnel handling hazardous chemical substances.

How to handle 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide safely?

2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide requires extreme caution during handling due to its Acute Tox. 1 classification and GHS06 skull and crossbones pictogram. Essential protective equipment includes chemical-resistant gloves, full face protection, and appropriate respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Only trained personnel should handle this substance following strict safety protocols.

How to store 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide correctly?

2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide must be stored in a secure, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed and store in original packaging with proper labeling. Due to its ADR Class 6.1 Group I classification, it requires storage in specialized facilities for highly toxic substances. Maintain controlled access and ensure storage areas comply with local regulations for hazardous chemical storage.

What to do in case of contact with 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide?

Immediate medical attention is required for any contact with 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide due to its extreme toxicity. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately. In case of eye contact, flush with clean water for 15 minutes. For ingestion, do not induce vomiting and seek emergency medical care immediately. Contact poison control center.

How to dispose of 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide properly?

2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide must be disposed of through licensed hazardous waste management facilities due to its high acute toxicity and environmental concerns. The substance cannot be disposed of through regular waste streams and requires specialized treatment. Contact certified waste disposal companies experienced in handling ADR Class 6.1 Group I materials. Follow all local and European regulations for hazardous chemical waste disposal including proper documentation and tracking.

How to transport 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide?

2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide is classified under ADR Class 6.1, Packing Group I, indicating highly toxic substances requiring strict transport regulations. Transportation must comply with dangerous goods regulations using approved packaging and proper labeling with GHS06 pictograms. Only certified carriers authorized to handle Class 6.1 materials can transport this substance. Documentation must include proper shipping names, hazard classes, and emergency response information throughout the transport chain.

Is 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide subject to specific regulations?

2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide is subject to strict European chemical regulations including REACH registration requirements and CLP classification as Acute Tox. 1 and 2. While not currently listed as an SVHC substance, its high toxicity classification subjects it to restricted use conditions. Companies must comply with occupational safety regulations, environmental protection measures, and proper risk assessment procedures. Professional users require appropriate authorization and safety training for handling such hazardous substances.

Where to buy 2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide in Europe?

2-diethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide is available through specialized chemical distributors like OYSI, a European supplier of technical chemicals. Due to its high toxicity classification and regulatory requirements, purchase is restricted to qualified professional users with appropriate licenses and safety infrastructure. OYSI provides technical support and ensures compliance with European chemical regulations for customers requiring this specialized organophosphorus compound for legitimate industrial applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.