2-chlorobenzaldehyde
C7H5ClO
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Identification
- CAS Number
- 89-98-5
- EC Number
- 201-956-3
- UN Number
- 3265
- Index Number
- 605-011-00-X
- PubChem CID
- 6996
Physical-chemical properties
- Molecular Formula
- C7H5ClO
- Molar Mass
- 140.56 g/mol
- IUPAC Name
- 2-chlorobenzaldehyde
Chemical Identifiers
- InChI
- InChI=1S/C7H5ClO/c8-7-4-2-1-3-6(7)5-9/h1-5H
- InChI Key
- FPYUJUBAXZAQNL-UHFFFAOYSA-N
Overview
2-chlorobenzaldehyde (CAS 89-98-5) is an aromatic aldehyde compound featuring a chlorine substituent at the ortho position of the benzaldehyde ring. This halogenated benzaldehyde derivative serves as a valuable intermediate in organic synthesis and chemical manufacturing processes. With its molecular formula C7H5ClO and molecular weight of 140.56 g/mol, 2-chlorobenzaldehyde exhibits the characteristic reactivity of both aromatic aldehydes and chlorinated organic compounds. The compound's structure combines the electrophilic aldehyde functionality with the electron-withdrawing effect of the chlorine atom, making it particularly useful for selective chemical transformations. From a safety perspective, 2-chlorobenzaldehyde is classified as Skin Corr. 1B under GHS regulations, requiring careful handling with appropriate personal protective equipment. The substance carries the danger signal word and displays the GHS05 pictogram, indicating its corrosive properties. Transportation falls under ADR Class 8, reflecting its corrosive nature during shipping and storage. Industrial applications of 2-chlorobenzaldehyde include pharmaceutical intermediate synthesis, where it serves as a building block for various active pharmaceutical ingredients. The compound also finds use in agrochemical manufacturing and specialty chemical production. Unlike simpler carboxylic acids such as butanoic acid or heptanoic acid, this aromatic aldehyde offers unique reactivity patterns that enable complex molecular constructions in synthetic chemistry. The chemical's versatility extends to dye and pigment manufacturing, where the aldehyde group facilitates condensation reactions essential for chromophore development. Its chlorinated aromatic structure provides stability while maintaining sufficient reactivity for further functionalization. OYSI maintains reliable supply chains for 2-chlorobenzaldehyde to support European industrial customers requiring this specialized chemical intermediate.
Safety & Classification
Skin Corr. 1B
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Causes severe skin burns and eye damage.
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3265 |
| ADR Class | 8 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | 2-Chlorbenzaldehyd |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-chlorobenzaldehyde?
2-chlorobenzaldehyde is an aromatic aldehyde compound with the molecular formula C7H5ClO and CAS number 89-98-5. This organic chemical features a benzene ring substituted with both a chlorine atom and an aldehyde functional group in the ortho position. With a molecular weight of 140.56 g/mol, it is classified as a corrosive substance (Skin Corr. 1B) requiring careful handling due to its hazardous properties.
What are the physicochemical properties of 2-chlorobenzaldehyde?
2-chlorobenzaldehyde is typically a colorless to pale yellow liquid at room temperature with a characteristic aromatic aldehyde odor. The compound has a molecular weight of 140.56 g/mol and contains both electron-withdrawing chlorine and aldehyde groups that influence its reactivity. It exhibits limited solubility in water but dissolves readily in organic solvents such as ethanol, ether, and benzene, making it suitable for various organic synthesis applications.
What is 2-chlorobenzaldehyde used for?
2-chlorobenzaldehyde serves as an important intermediate in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of various chemical compounds including pharmaceuticals, agrochemicals, and specialty chemicals. The compound acts as a building block for synthesizing more complex molecules, particularly in the development of medicinal compounds and fine chemicals. Its aldehyde functionality makes it valuable for condensation reactions and other organic transformations in industrial processes.
How to handle 2-chlorobenzaldehyde safely?
2-chlorobenzaldehyde requires careful handling due to its corrosive properties (Skin Corr. 1B classification). Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation exposure. The GHS05 pictogram indicates corrosive hazards, requiring immediate attention to prevent serious skin and eye damage upon contact.
How to store 2-chlorobenzaldehyde correctly?
2-chlorobenzaldehyde should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and direct sunlight. As a corrosive substance, it must be kept separate from incompatible materials such as strong bases, oxidizing agents, and metals. Storage containers should be made of compatible materials resistant to corrosion. Regular inspection of containers is essential to prevent leaks and ensure proper containment of this hazardous chemical.
What to do in case of contact with 2-chlorobenzaldehyde?
Immediate action is critical due to 2-chlorobenzaldehyde's corrosive nature. For skin contact, immediately remove contaminated clothing and flush the affected area with plenty of water for at least 15 minutes. In case of eye contact, rinse immediately with water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and seek medical help if breathing difficulties occur. Always consult a physician after any significant exposure.
How to dispose of 2-chlorobenzaldehyde properly?
2-chlorobenzaldehyde must be disposed of as hazardous waste according to local and national regulations. The substance cannot be discharged into sewers or the environment due to its corrosive and potentially harmful properties. Disposal should only be carried out by licensed waste management companies specializing in hazardous chemical waste. Containers must be properly labeled and handled according to waste classification requirements to ensure environmental protection and regulatory compliance.
How to transport 2-chlorobenzaldehyde?
2-chlorobenzaldehyde is classified under ADR Class 8 (corrosive substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation for safe transport. Vehicles must display appropriate hazard placards, and drivers need ADR certification for transporting corrosive materials. Proper packaging must meet UN specifications for corrosive substances, ensuring secure containment during transit and compliance with international dangerous goods regulations.
Is 2-chlorobenzaldehyde subject to specific regulations?
2-chlorobenzaldehyde is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification as a corrosive substance (Skin Corr. 1B). The compound is not currently listed as a Substance of Very High Concern (SVHC) under REACH. However, its corrosive classification requires compliance with occupational safety standards, proper labeling with GHS05 pictograms, and adherence to workplace exposure limits where established by local authorities.
Where to buy 2-chlorobenzaldehyde in Europe?
2-chlorobenzaldehyde is available through OYSI, a specialized European distributor of chemical products serving industrial and research customers across Europe. As an established chemical distributor, OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance support. Professional customers can obtain detailed product information, availability, and technical support through OYSI's distribution network, ensuring reliable supply for their chemical synthesis and manufacturing requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.