Propanoyl propanoate

C6H10O3

propanoyl propanoate

CAS123-62-6
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
123-62-6
EC Number
204-638-2
UN Number
2496
Index Number
607-010-00-X
PubChem CID
31263

Physical-chemical properties

Molecular Formula
C6H10O3
Molar Mass
130.14 g/mol
IUPAC Name
propanoyl propanoate

Chemical Identifiers

InChI
InChI=1S/C6H10O3/c1-3-5(7)9-6(8)4-2/h3-4H2,1-2H3
InChI Key
WYVAMUWZEOHJOQ-UHFFFAOYSA-N

Overview

Propanoyl propanoate (CAS 123-62-6) is an organic chemical compound classified as an anhydride with corrosive properties and industrial applications in chemical synthesis. This chemical substance, also known by its IUPAC designation propanoyl propanoate, belongs to the family of acid anhydrides derived from propanoic acid. With the molecular formula C6H10O3 and a molecular weight of 130.14 g/mol, this compound exhibits the characteristic reactivity patterns typical of anhydrides, making it a valuable intermediate in various chemical processes. The substance is assigned EC number 204-638-2 and falls under the regulatory framework governing corrosive chemicals. From a safety perspective, propanoyl propanoate is classified as Skin Corr. 1B under the GHS system, indicating severe skin corrosion potential. The substance carries the "Danger" signal word and is marked with the GHS05 pictogram, warning of its corrosive nature. For transportation purposes, it is classified under ADR Class 8, reflecting its corrosive properties that require specialized handling and storage protocols. The compound finds applications in organic synthesis as an acylating agent, particularly in pharmaceutical intermediate production and specialty chemical manufacturing. Its reactivity with nucleophiles makes it useful in esterification reactions and as a building block for more complex molecular structures. Unlike simpler carboxylic acids such as butanoic acid, propanoyl propanoate offers enhanced reactivity due to its anhydride functionality, making it particularly valuable in controlled synthetic environments. Industrial applications also extend to polymer chemistry and surface treatment processes, where its acylating properties contribute to material modification and functionalization reactions. OYSI provides propanoyl propanoate to European industrial customers, ensuring compliance with regional chemical regulations and quality standards.

Safety & Classification

Danger
Classification:

Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2496
ADR Class8
Packing GroupIII
Tunnel CodeE
Proper Shipping NamePropionsäureanhydrid
Marine PollutantNo

Frequently Asked Questions

What is propanoyl propanoate?

Propanoyl propanoate is an organic chemical compound with the molecular formula C6H10O3 and CAS number 123-62-6. This ester has a molecular weight of 130.14 g/mol and belongs to the class of propanoic acid derivatives. It is classified as a corrosive substance (Skin Corr. 1B) under the GHS system, requiring careful handling due to its potential to cause severe skin burns and eye damage upon contact.

What are the physicochemical properties of propanoyl propanoate?

Propanoyl propanoate is typically a colorless to pale yellow liquid at room temperature with a characteristic ester odor. As an organic ester compound, it exhibits limited solubility in water but shows good miscibility with organic solvents such as alcohols, ethers, and hydrocarbons. The compound has a density slightly lower than water and possesses typical ester reactivity patterns, being susceptible to hydrolysis under acidic or basic conditions.

What is propanoyl propanoate used for?

Propanoyl propanoate serves primarily as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. It is utilized in the production of various organic compounds, acting as an acylating agent in chemical reactions. The compound finds applications in specialty chemical synthesis, research laboratories, and as a reagent in organic chemistry processes. Its ester functionality makes it valuable for creating more complex molecular structures in industrial chemical processes.

How to handle propanoyl propanoate safely?

Propanoyl propanoate must be handled with extreme caution due to its corrosive nature (Skin Corr. 1B classification). Essential personal protective equipment includes chemical-resistant gloves, safety goggles, face shields, and protective clothing covering all exposed skin. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct contact with skin, eyes, and clothing, and ensure emergency shower and eyewash stations are readily accessible.

How to store propanoyl propanoate correctly?

Propanoyl propanoate should be stored in tightly sealed, corrosion-resistant containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers away from incompatible materials such as strong bases, strong acids, and oxidizing agents. Storage areas must be equipped with appropriate spill containment measures and emergency equipment. Ensure proper labeling with hazard warnings and maintain inventory records for regulatory compliance.

What to do in case of contact with propanoyl propanoate?

Immediate action is crucial due to the corrosive nature of propanoyl propanoate. For skin contact, immediately remove contaminated clothing and flush the affected area with copious amounts of water for at least 15 minutes. For eye contact, rinse immediately with water for at least 15 minutes while holding eyelids open. Remove contact lenses if present and easily removable. Seek immediate medical attention for all exposures and provide the safety data sheet to medical personnel.

How to dispose of propanoyl propanoate appropriately?

Propanoyl propanoate waste must be disposed of as hazardous chemical waste according to local and national environmental regulations. Contact licensed hazardous waste disposal companies for proper treatment and disposal services. Never discharge into sewers, waterways, or soil. Small quantities may be neutralized under controlled conditions by qualified personnel, but this should follow established laboratory waste procedures. Maintain proper documentation of all disposal activities for regulatory compliance.

How to transport propanoyl propanoate?

Propanoyl propanoate is classified under ADR Class 8 (corrosive substances), Packing Group III for transportation purposes. It must be packaged in UN-approved containers suitable for corrosive liquids and properly labeled with appropriate hazard markings and documentation. Transportation requires compliance with ADR regulations including proper placarding, driver training, and emergency response information. Shipping documents must include the correct UN identification number and hazard class information.

Is propanoyl propanoate subject to specific regulations?

Propanoyl propanoate is subject to various chemical regulations including REACH registration requirements in the European Union and CLP classification as a corrosive substance. It is not currently listed as a Substance of Very High Concern (SVHC). Companies must comply with workplace safety regulations, environmental discharge limits, and proper hazard communication requirements. Regular safety data sheet updates and employee training on handling procedures are mandatory regulatory requirements.

Where to buy propanoyl propanoate in Europe?

Propanoyl propanoate is available through OYSI, a leading European distributor of specialty chemicals serving industrial and research customers across Europe. OYSI provides high-quality propanoyl propanoate with proper documentation, safety data sheets, and regulatory compliance support. As an established chemical distributor, OYSI ensures reliable supply chains and technical support for customers requiring this corrosive chemical intermediate for their industrial applications and research projects.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.