2-chloroacetonitrile

2-chloroacetonitrile is an organochlorine compound with the molecular formula C2H2ClN and CAS number 107-14-2. This chemical substance has a molecular weight of 75.5 g/mol and belongs to the nitrile family. It is classified as a highly toxic substance with acute toxicity properties and environmental hazards. The compound is regulated under various safety frameworks due to its dangerous nature and requires careful handling in industrial applications.

2-chloroacetonitrile is a colorless to pale yellow liquid at room temperature with a characteristic pungent odor. The compound is miscible with water and most organic solvents, making it highly soluble in various media. It has a boiling point around 124°C and a density higher than water. The substance is chemically reactive due to both the nitrile group and the chlorine substituent, which influences its handling and storage requirements.

2-chloroacetonitrile serves primarily as an intermediate in pharmaceutical and agrochemical synthesis. It is used in the production of various pharmaceutical compounds, pesticides, and herbicides. The compound acts as a building block for creating more complex molecules through nucleophilic substitution reactions. Additionally, it finds application in organic synthesis laboratories for research purposes and in the manufacture of specialty chemicals where its reactive nitrile and chlorine functionalities are utilized.

2-chloroacetonitrile requires strict safety protocols due to its Acute Tox. 3 classification and GHS06 pictogram. Personal protective equipment must include chemical-resistant gloves, safety goggles, and appropriate respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin and eye contact, and prevent inhalation of vapors. Emergency shower and eyewash stations should be readily accessible, and personnel must be trained in proper handling procedures.

2-chloroacetonitrile must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. The storage area should be equipped with appropriate spill containment measures and fire suppression systems. Keep containers upright and protect from physical damage. Store separately from incompatible materials such as strong bases, oxidizing agents, and reducing agents. Access should be restricted to authorized personnel only.

Immediate action is critical due to the acute toxicity of 2-chloroacetonitrile. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for at least 15 minutes. If inhaled, move person to fresh air immediately. For ingestion, do not induce vomiting. Seek immediate medical attention in all cases and provide safety data sheet to medical personnel.

2-chloroacetonitrile disposal must comply with local, national, and international hazardous waste regulations due to its toxic and environmental hazard classifications. The substance cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment facilities. Incineration at high temperatures in approved facilities is typically the preferred disposal method. Contact licensed waste disposal companies and provide complete chemical identification and safety data for proper handling and treatment.

2-chloroacetonitrile is classified under ADR Class 6.1 (toxic substances) Packing Group I, indicating high toxicity requiring strict transport regulations. Packages must bear appropriate hazard labels including GHS06 and GHS09 pictograms with 'Danger' signal word. Transportation requires specialized packaging, proper documentation, and trained personnel. Vehicles must carry emergency response information and appropriate spill response materials. Only authorized carriers experienced in dangerous goods transport should handle shipments.

2-chloroacetonitrile is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The substance falls under toxic chemical regulations due to its Acute Tox. 3 classification and environmental hazard properties. While not currently listed as an SVHC, it requires safety data sheets, proper labeling, and compliance with occupational exposure limits. Import/export may require additional permits depending on regional regulations and intended use.

2-chloroacetonitrile is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substances. OYSI provides proper documentation, safety data sheets, and ensures compliance with European chemical regulations including REACH and CLP requirements. As a professional chemical supplier, OYSI offers technical support and guidance for safe handling, storage, and regulatory compliance to industrial customers across Europe requiring this specialized chemical intermediate.