2-(2,2-dimethylpropanoyl)indene-1,3-dione
C14H14O3
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Identification
- CAS Number
- 83-26-1
- EC Number
- 201-462-8
- UN Number
- 2588
- Index Number
- 606-016-00-X
- PubChem CID
- 6732
Physical-chemical properties
- Molecular Formula
- C14H14O3
- Molar Mass
- 230.26 g/mol
- IUPAC Name
- 2-(2,2-dimethylpropanoyl)indene-1,3-dione
Chemical Identifiers
- InChI
- InChI=1S/C14H14O3/c1-14(2,3)13(17)10-11(15)8-6-4-5-7-9(8)12(10)16/h4-7,10H,1-3H3
- InChI Key
- RZKYEQDPDZUERB-UHFFFAOYSA-N
Overview
2-(2,2-dimethylpropanoyl)indene-1,3-dione (CAS 83-26-1) is an organic compound featuring an indene-1,3-dione core structure with significant toxicological properties requiring careful handling protocols. This chemical compound, also identified by EC number 201-462-8, belongs to the indanedione family and exhibits a molecular formula of C14H14O3 with a molecular weight of 230.26 g/mol. The substance is characterized by its distinctive bicyclic structure incorporating a pivaloyl substituent, which contributes to its specific chemical reactivity and biological activity profile. As a member of the indanedione class, this compound shares certain structural similarities with other aromatic compounds, though its toxicological profile differs significantly from substances like N-methylaniline or phenylhydrazine, which possess different functional groups and associated hazard classifications. The compound presents serious safety considerations, classified under multiple hazard categories including Acute Toxicity Category 3, Specific Target Organ Toxicity Repeat Exposure Category 1, and acute and chronic aquatic toxicity. These classifications necessitate implementation of stringent safety protocols during handling, storage, and transportation. The substance requires ADR Class 6.1 transportation classification and displays GHS pictograms indicating acute toxicity, health hazards, and environmental dangers. Industrial applications for 2-(2,2-dimethylpropanoyl)indene-1,3-dione typically include use as a chemical intermediate in pharmaceutical synthesis, specialty organic synthesis reactions, and as a research chemical for academic and industrial laboratories. The compound serves particular utility in developing anticoagulant compounds and related pharmaceutical research applications. OYSI maintains reliable supply chains for this specialized chemical compound, ensuring consistent availability for qualified industrial customers requiring this technical-grade substance for legitimate commercial applications.
Safety & Classification
Acute Tox. 3 *; STOT RE 1; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2588 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Pindon (ISO) |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-(2,2-dimethylpropanoyl)indene-1,3-dione?
2-(2,2-dimethylpropanoyl)indene-1,3-dione is an organic chemical compound with the molecular formula C14H14O3 and CAS number 83-26-1. This substance belongs to the indandione family and has a molecular weight of 230.26 g/mol. It is classified as a hazardous substance requiring careful handling due to its toxic properties and environmental impact potential.
What are the physicochemical properties of 2-(2,2-dimethylpropanoyl)indene-1,3-dione?
2-(2,2-dimethylpropanoyl)indene-1,3-dione is a solid organic compound at room temperature with a complex aromatic structure. The molecule contains both ketone and indene functional groups, contributing to its chemical reactivity. Its molecular weight of 230.26 g/mol indicates moderate molecular size, and its structure suggests limited water solubility but good solubility in organic solvents.
What is 2-(2,2-dimethylpropanoyl)indene-1,3-dione used for?
2-(2,2-dimethylpropanoyl)indene-1,3-dione is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its indandione structure makes it valuable in the production of anticoagulant compounds and other pharmaceutical applications. It may also serve as a precursor in fine chemical synthesis and research applications within the pharmaceutical and chemical industries.
How to handle 2-(2,2-dimethylpropanoyl)indene-1,3-dione safely?
2-(2,2-dimethylpropanoyl)indene-1,3-dione requires careful handling due to its Acute Tox. 3 and STOT RE 1 classifications. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Ensure emergency procedures are in place and personnel are trained in safe handling practices.
How to store 2-(2,2-dimethylpropanoyl)indene-1,3-dione correctly?
2-(2,2-dimethylpropanoyl)indene-1,3-dione should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers properly labeled and segregated from food, feed, and water supplies. Storage areas should be equipped with appropriate spill containment measures and restricted access due to the substance's toxic properties and environmental hazards.
What to do in case of contact with 2-(2,2-dimethylpropanoyl)indene-1,3-dione?
In case of skin contact with 2-(2,2-dimethylpropanoyl)indene-1,3-dione, immediately remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. For eye contact, flush with water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for complete first aid procedures.
How to dispose of 2-(2,2-dimethylpropanoyl)indene-1,3-dione appropriately?
2-(2,2-dimethylpropanoyl)indene-1,3-dione must be disposed of as hazardous waste according to local and national regulations. Contact licensed waste disposal companies specialized in toxic and environmentally hazardous substances. Never dispose of this substance in regular waste streams, sewers, or the environment due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Maintain proper documentation of disposal activities as required by regulations.
How to transport 2-(2,2-dimethylpropanoyl)indene-1,3-dione?
2-(2,2-dimethylpropanoyl)indene-1,3-dione is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation. Use appropriate UN-specification packaging and ensure proper labeling with GHS06, GHS08, and GHS09 pictograms. Transport documents must include proper shipping names and hazard classifications. Only use carriers authorized to transport Class 6.1 substances and ensure emergency response information is available during transport.
Is 2-(2,2-dimethylpropanoyl)indene-1,3-dione subject to particular regulations?
2-(2,2-dimethylpropanoyl)indene-1,3-dione is subject to REACH regulation for registration and evaluation in the European Union. It must be classified and labeled according to CLP regulation with Danger signal word and appropriate pictograms (GHS06, GHS08, GHS09). The substance is not currently listed as SVHC but requires compliance with occupational exposure limits and environmental protection measures due to its hazardous properties.
Where to buy 2-(2,2-dimethylpropanoyl)indene-1,3-dione in Europe?
2-(2,2-dimethylpropanoyl)indene-1,3-dione is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this substance to pharmaceutical, research, and industrial customers across Europe with appropriate documentation including safety data sheets and certificates of analysis. Contact OYSI directly for availability, specifications, and regulatory compliance information to ensure proper sourcing for your specific applications.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.