2-(2-aminoethylamino)ethanol

C4H12N2O

CAS111-41-1
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

Consulting for 2-(2-aminoethylamino)ethanol

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Identification

CAS Number
111-41-1
EC Number
203-867-5
UN Number
2735
Index Number
603-194-00-0
PubChem CID
8112

Physical-chemical properties

Molecular Formula
C4H12N2O
Molar Mass
104.15 g/mol
IUPAC Name
2-(2-aminoethylamino)ethanol

Chemical Identifiers

InChI
InChI=1S/C4H12N2O/c5-1-2-6-3-4-7/h6-7H,1-5H2
InChI Key
LHIJANUOQQMGNT-UHFFFAOYSA-N

Overview

2-(2-aminoethylamino)ethanol (CAS 111-41-1) is an organic amine compound with hydroxyl functionality and corrosive properties. This versatile chemical intermediate, also known by its IUPAC designation 2-(2-aminoethylamino)ethanol, serves as a crucial building block in various industrial applications. With the molecular formula C4H12N2O and a molecular weight of 104.15 g/mol, this compound features both primary and secondary amine groups alongside a hydroxyl functional group, making it highly reactive and useful for chemical synthesis processes. The compound exhibits significant hazard characteristics, classified as a Category 1B reproductive toxicant, skin corrosive substance, and skin sensitizer according to CLP regulation. Its corrosive nature is reflected in the GHS pictograms GHS05, GHS07, and GHS08, with a danger signal word indicating serious health risks upon exposure. Transportation falls under ADR Class 8 due to its corrosive properties, requiring appropriate handling and storage protocols. In industrial applications, 2-(2-aminoethylamino)ethanol functions primarily as an intermediate in pharmaceutical synthesis, particularly for active pharmaceutical ingredients requiring diamine functionality. It also serves in the production of specialty polymers and as a curing agent for epoxy resins, where its dual amine structure provides excellent crosslinking properties. The compound finds additional use in the manufacture of chelating agents and corrosion inhibitors, similar to applications involving ethane-1,2-diamine. The presence of both hydrophilic hydroxyl and basic amine groups makes this compound particularly suitable for applications requiring water solubility and pH adjustment capabilities. Its reactivity profile allows for various derivatization reactions in fine chemical synthesis. OYSI maintains reliable supply chains for 2-(2-aminoethylamino)ethanol to support European industrial customers requiring consistent quality and technical support.

Safety & Classification

Danger
Classification:

Repr. 1B; Skin Corr. 1B; Skin Sens. 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H314

Causes severe skin burns and eye damage.

H317

May cause an allergic skin reaction.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2735
ADR Class8
Packing GroupII
Tunnel CodeE
Proper Shipping NameN-(2-Aminoethyl)-ethanolamin
Marine PollutantNo

Frequently Asked Questions

What is 2-(2-aminoethylamino)ethanol?

2-(2-aminoethylamino)ethanol is an organic chemical compound with the molecular formula C4H12N2O and CAS number 111-41-1. This diamine alcohol has a molecular weight of 104.15 g/mol and belongs to the family of ethanolamines. It is classified as a hazardous substance with reproductive toxicity (Repr. 1B), severe skin corrosion (Skin Corr. 1B), and skin sensitization (Skin Sens. 1) properties, requiring careful handling and appropriate safety measures.

What are the physicochemical properties of 2-(2-aminoethylamino)ethanol?

2-(2-aminoethylamino)ethanol is typically a viscous liquid at room temperature with hygroscopic properties, meaning it readily absorbs moisture from air. The compound is highly soluble in water due to its polar amine and hydroxyl functional groups. It exhibits basic properties due to the presence of two amino groups and can form hydrogen bonds through its hydroxyl group. The substance may have an amine-like odor and should be handled under controlled conditions.

What is 2-(2-aminoethylamino)ethanol used for?

2-(2-aminoethylamino)ethanol is primarily used as an intermediate in chemical synthesis and manufacturing processes. It serves as a building block for the production of surfactants, corrosion inhibitors, and specialty chemicals. The compound is also utilized in the formulation of metalworking fluids, textile processing agents, and as a curing agent for epoxy resins. Its dual amine functionality makes it valuable in polymer chemistry and pharmaceutical intermediate synthesis.

How to handle 2-(2-aminoethylamino)ethanol safely?

2-(2-aminoethylamino)ethanol requires strict safety protocols due to its corrosive and sensitizing properties. Personal protective equipment must include chemical-resistant gloves, safety goggles, face shields, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation. Given its reproductive toxicity classification (Repr. 1B), pregnant workers should avoid exposure. Emergency eyewash stations and safety showers must be readily accessible.

How to store 2-(2-aminoethylamino)ethanol correctly?

2-(2-aminoethylamino)ethanol should be stored in tightly sealed containers made of compatible materials, away from heat sources, ignition sources, and incompatible substances. Storage areas must be cool, dry, and well-ventilated to prevent vapor accumulation. The substance should be kept away from acids, oxidizing agents, and reactive metals. Secondary containment is recommended due to its corrosive nature. Storage facilities should comply with local regulations for hazardous materials and include appropriate spill control measures.

What to do in case of contact with 2-(2-aminoethylamino)ethanol?

2-(2-aminoethylamino)ethanol contact requires immediate emergency response due to its corrosive properties. For skin contact, immediately remove contaminated clothing and flush affected area with copious amounts of water for at least 15 minutes. In case of eye contact, rinse immediately with water for at least 15 minutes and seek medical attention urgently. If inhaled, move the person to fresh air and seek medical advice. For ingestion, do not induce vomiting and seek immediate medical attention.

How to dispose of 2-(2-aminoethylamino)ethanol appropriately?

2-(2-aminoethylamino)ethanol disposal must comply with local, national, and international waste regulations due to its hazardous classification. The substance cannot be disposed of in regular waste streams and requires treatment as hazardous chemical waste. Disposal should be conducted through licensed waste management companies specializing in hazardous materials. Small quantities may be neutralized under controlled conditions before disposal, but this should only be done by qualified personnel following approved procedures and environmental regulations.

How to transport 2-(2-aminoethylamino)ethanol?

2-(2-aminoethylamino)ethanol is classified under ADR Class 8 (corrosive substances), Packing Group II, indicating it poses significant transport hazards. Transportation requires appropriate UN-specification packaging designed for corrosive materials and proper hazard labeling including corrosive placards. Vehicles must carry appropriate emergency response information and spill control materials. Drivers require ADR training for dangerous goods transport. All transport documentation must include proper shipping names, hazard classifications, and emergency contact information according to ADR regulations.

Is 2-(2-aminoethylamino)ethanol subject to specific regulations?

2-(2-aminoethylamino)ethanol is subject to comprehensive European chemical regulations including REACH registration requirements and CLP classification obligations. While not currently listed as a Substance of Very High Concern (SVHC), its Repr. 1B classification subjects it to strict handling and labeling requirements under CLP regulation. The substance may be subject to workplace exposure limits and requires safety data sheets for commercial supply. Companies handling this chemical must ensure compliance with occupational health regulations and environmental protection standards.

Where to buy 2-(2-aminoethylamino)ethanol in Europe?

2-(2-aminoethylamino)ethanol is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. OYSI provides this substance with full regulatory compliance including proper CLP labeling, safety data sheets, and transport documentation. As a professional chemical distributor, OYSI ensures product quality, regulatory compliance, and technical support for industrial applications. Contact OYSI directly for availability, specifications, packaging options, and delivery throughout European markets for your specific industrial requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.