[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate

[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate is a tropane alkaloid derivative with the molecular formula C17H23NO3 and CAS number 51-55-8. This compound features a bicyclic tropane structure linked to a phenylpropanoate ester group. With a molecular weight of 289.4 g/mol, it belongs to the class of highly toxic substances, classified as Acute Tox. 2 under GHS regulations, requiring careful handling due to its significant toxicological properties.

[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate is an organic compound with molecular formula C17H23NO3 and molecular weight 289.4 g/mol. As a tropane alkaloid ester, it typically appears as a crystalline solid at room temperature. The compound contains both hydrophilic (hydroxyl and amine groups) and lipophilic (phenyl and bicyclic) regions, affecting its solubility profile. Its stereochemistry is specifically defined with (1S,5R) configuration at the bicyclic system.

[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate is primarily used in pharmaceutical research and analytical chemistry applications. Due to its tropane alkaloid structure, it serves as a reference standard in analytical laboratories and research institutions. The compound may also be utilized in medicinal chemistry research for studying structure-activity relationships. Given its high toxicity classification (Acute Tox. 2), its use is restricted to specialized professional applications under controlled laboratory conditions.

[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate requires extreme caution due to its Acute Tox. 2 classification and GHS06 pictogram. Essential PPE includes chemical-resistant gloves, safety goggles, and laboratory coats. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Use only the minimum quantities necessary and ensure proper training before handling. Emergency equipment should be readily available, and work should be performed by qualified personnel only.

[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate must be stored in a secure, locked chemical storage area due to its high toxicity (Acute Tox. 2). Keep containers tightly closed in a cool, dry, well-ventilated location away from heat and ignition sources. Store separately from incompatible materials including strong oxidizers and acids. Access should be restricted to authorized personnel only. Regular inventory checks and proper labeling with GHS06 hazard symbols are essential for safe storage management.

Immediate medical attention is required for any contact with [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate due to its Acute Tox. 2 classification. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately. In case of eye contact, flush with water for 15 minutes. If ingested, do not induce vomiting and seek immediate medical care. Always contact poison control or emergency services promptly.

[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate must be disposed of as hazardous waste due to its high toxicity classification. Contact licensed hazardous waste disposal companies for proper handling and destruction. Never dispose of in regular waste, drains, or sewage systems. Small laboratory quantities should be collected in appropriate hazardous waste containers and labeled clearly. Follow local and national regulations for hazardous waste disposal, and maintain disposal records as required by environmental authorities.

[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate is classified as ADR Class 6.1, Packing Group I, indicating high toxicity for transport purposes. Shipments require proper dangerous goods packaging, labeling with toxic substance markings, and appropriate shipping documentation. Only certified dangerous goods carriers can transport this material. Packaging must meet UN specification requirements for Packing Group I substances. Emergency response information and safety data sheets must accompany all shipments to ensure safe handling during transport.

[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate is subject to extensive regulatory oversight due to its high toxicity. Under CLP regulation, it carries Acute Tox. 2 classification with mandatory GHS06 labeling. REACH registration may be required for commercial use in the EU. The compound is not currently listed as SVHC, but its toxicity profile means it may be subject to additional restrictions. Transport regulations under ADR Class 6.1 apply, and local controlled substance regulations should be verified before purchase or use.

[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate is available through OYSI, a specialized European distributor of high-quality chemical products. As a highly toxic substance (Acute Tox. 2), procurement requires proper authorization and compliance verification. OYSI ensures full regulatory compliance, proper packaging, and safe delivery throughout Europe. Due to the compound's toxicity classification and transport restrictions (ADR 6.1, Group I), purchases are limited to qualified research institutions and licensed facilities with appropriate handling capabilities.