[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate

C15H21N3O2

CAS57-47-6
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
57-47-6
EC Number
200-332-8
UN Number
1544
Index Number
614-020-00-8
PubChem CID
5983

Physical-chemical properties

Molecular Formula
C15H21N3O2
Molar Mass
275.35 g/mol
IUPAC Name
[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate

Chemical Identifiers

InChI
InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1
InChI Key
PIJVFDBKTWXHHD-HIFRSBDPSA-N

Overview

[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate (CAS 57-47-6) is a carbamate insecticide with potent cholinesterase inhibition properties used in pest control applications. This compound, with molecular formula C15H21N3O2 and molecular weight 275.35 g/mol, belongs to the carbamate class of insecticides and represents a significant technical chemical in agricultural and industrial pest management. The substance features a complex pyrroloindole ring system with specific stereochemical configuration, contributing to its biological activity profile. Its systematic structure incorporates methylcarbamate functionality, which is responsible for the reversible inhibition of acetylcholinesterase in target organisms. The compound exhibits high acute toxicity, classified as Acute Tox. 2 under the Globally Harmonized System, requiring the danger signal word and GHS06 pictogram for skull and crossbones. Transportation falls under ADR Class 6.1, reflecting its toxic properties. These safety characteristics necessitate specialized handling protocols, appropriate personal protective equipment, and secure storage conditions in controlled environments. Primary industrial applications include formulation into agricultural pesticides for crop protection, specialty pest control products for commercial use, and integration into integrated pest management systems. The compound's efficacy profile makes it valuable for controlling various insect species while maintaining relatively shorter environmental persistence compared to organochlorine alternatives. Unlike related compounds such as (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one, this carbamate offers specific advantages in targeted pest control applications. OYSI supplies this technical chemical to qualified industrial customers throughout Europe, ensuring full regulatory compliance and comprehensive technical support for specialized applications.

Safety & Classification

Danger
Classification:

Acute Tox. 2 *; Acute Tox. 2 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H330

Fatal if inhaled.

H300

Fatal if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1544
ADR Class6.1
Packing GroupI
Tunnel CodeC/E
Proper Shipping NamePhysostigmin
Marine PollutantNo

Frequently Asked Questions

What is [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate?

[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate is a carbamate compound with the molecular formula C15H21N3O2 and CAS number 57-47-6. This organic chemical has a molecular weight of 275.35 g/mol and features a complex pyrroloindole structure with a methylcarbamate functional group. It is classified as a highly toxic substance requiring careful handling and specialized safety measures.

What are the physicochemical properties of [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate?

[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate is an organic compound with molecular formula C15H21N3O2 and molecular weight 275.35 g/mol. As a carbamate derivative, it typically exists as a crystalline solid at room temperature. The compound contains nitrogen-bearing heterocycles which influence its solubility characteristics and chemical reactivity. Specific physical properties such as melting point and solubility should be verified from the supplier's technical documentation.

What is [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate used for?

[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate is primarily used in pharmaceutical research and chemical synthesis applications. Its complex pyrroloindole structure makes it valuable as a research intermediate or reference standard in analytical chemistry. Due to its high toxicity classification (Acute Tox. 2), its use is restricted to specialized industrial and research applications where appropriate safety controls are in place.

How to handle [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate safely?

[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate requires maximum safety precautions due to its Acute Tox. 2 classification. Mandatory personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Only trained personnel should handle this substance, and emergency procedures must be readily available.

How to store [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate correctly?

[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate must be stored in a secure, locked chemical storage area with restricted access due to its high toxicity. Keep containers tightly sealed in a cool, dry place away from incompatible materials. Storage areas should have appropriate ventilation and spill containment measures. The substance should be segregated from oxidizing agents, acids, and bases. Regular inventory checks and proper labeling are essential.

What to do in case of contact with [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate?

Immediate medical attention is required for any contact with [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate due to its Acute Tox. 2 classification. For skin contact, remove contaminated clothing and rinse thoroughly with water. If inhaled, move to fresh air immediately. For eye contact, flush with clean water for at least 15 minutes. Never induce vomiting if ingested. Contact emergency services immediately and provide the safety data sheet to medical personnel.

How to dispose of [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate properly?

[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate must be disposed of as hazardous waste through licensed waste disposal companies due to its high toxicity classification. The waste requires special handling and cannot be disposed of in regular waste streams. Disposal must comply with local, national, and EU waste regulations. Empty containers should also be treated as hazardous waste. Maintain complete documentation of all disposal activities for regulatory compliance.

How to transport [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate?

[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate is classified as ADR Class 6.1, Packing Group I, indicating highly toxic substances requiring maximum transport safety measures. Specialized packaging, labeling, and documentation are mandatory. Only certified dangerous goods carriers can transport this material. Vehicles must carry appropriate emergency equipment and drivers require ADR certification. Shipments must include proper dangerous goods declarations and emergency response information.

Is [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate subject to special regulations?

[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate is subject to comprehensive chemical regulations including REACH registration requirements and CLP classification as Acute Tox. 2. While not currently listed as an SVHC, its high toxicity classification subjects it to strict handling, storage, and transport regulations. Companies must maintain safety data sheets, conduct risk assessments, and implement appropriate risk management measures. Import/export may require additional permits depending on jurisdiction.

Where to buy [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate in Europe?

[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate is available through OYSI, a specialized European distributor of technical chemicals. Due to its high toxicity classification and regulatory requirements, purchase is restricted to qualified industrial and research users with appropriate safety facilities. Buyers must demonstrate proper handling capabilities and regulatory compliance. Contact OYSI directly for availability, technical specifications, and regulatory documentation required for this controlled substance.

Services for [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate

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[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate is a dangerous good. We support you with labeling, packaging, and transport documentation.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.