1H-indole-5,6-diol

1H-indole-5,6-diol is an organic compound with the molecular formula C8H7NO2 and CAS number 3131-52-0. It belongs to the indole family, featuring a bicyclic structure with two hydroxyl groups positioned at the 5 and 6 positions of the indole ring. With a molecular weight of 149.15 g/mol, this compound is classified as hazardous with acute toxicity, eye damage, and aquatic chronic toxicity properties.

1H-indole-5,6-diol is a solid organic compound at room temperature with a molecular weight of 149.15 g/mol. The presence of hydroxyl groups and the nitrogen atom in the indole ring system influences its polarity and potential hydrogen bonding capabilities. Due to its phenolic structure, it likely exhibits limited water solubility but may dissolve in polar organic solvents.

1H-indole-5,6-diol is primarily used as an intermediate in pharmaceutical and chemical synthesis. Its indole structure makes it valuable for developing pharmaceutical compounds, particularly those targeting neurological pathways. It may also serve as a building block in the synthesis of more complex organic molecules and research applications in biochemical studies involving indole derivatives.

1H-indole-5,6-diol requires careful handling due to its Acute Tox. 4 and Eye Dam. 1 classifications. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in a well-ventilated area or under a fume hood to avoid inhalation. Prevent skin and eye contact, and ensure proper training before handling this substance.

1H-indole-5,6-diol should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed and properly labeled. Store away from incompatible materials and ensure appropriate containment to prevent environmental release. The storage area should be equipped with appropriate safety equipment and restricted to authorized personnel only.

In case of eye contact with 1H-indole-5,6-diol, immediately flush with plenty of water for at least 15 minutes and seek immediate medical attention due to its Eye Dam. 1 classification. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. If ingested, do not induce vomiting and seek medical advice immediately. Always consult safety data sheets for complete first aid procedures.

1H-indole-5,6-diol must be disposed of according to local, national, and international waste regulations. Due to its hazardous classification and aquatic chronic toxicity, it requires specialized hazardous waste disposal through licensed waste management companies. Never dispose of it in regular waste streams or down drains. Consult local environmental authorities for specific disposal requirements and approved disposal facilities.

1H-indole-5,6-diol is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III. Transport must comply with international dangerous goods regulations including proper packaging, labeling, and documentation. Use UN-approved packaging and ensure proper marking with hazard labels. Transportation should be handled by qualified personnel familiar with dangerous goods regulations and emergency procedures.

1H-indole-5,6-diol is subject to CLP regulation classification with GHS pictograms GHS07, GHS05, and GHS09, requiring appropriate labeling and safety data sheets. It falls under REACH regulation requirements for registration and chemical safety assessment. The compound is not currently listed as a SVHC (Substance of Very High Concern), but users must comply with occupational exposure limits and environmental protection measures.

1H-indole-5,6-diol is available through OYSI, a European distributor of technical chemicals. OYSI provides this compound with full regulatory compliance including proper classification, labeling, and safety documentation. As a specialized chemical distributor, OYSI ensures quality products meeting European standards and provides technical support for industrial and research applications across European markets.