1,3-dichloropropan-2-ol

C3H6Cl2O

CAS96-23-1
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
96-23-1
EC Number
202-491-9
UN Number
2750
Index Number
602-064-00-0
PubChem CID
7289

Physical-chemical properties

Molecular Formula
C3H6Cl2O
Molar Mass
128.98 g/mol
IUPAC Name
1,3-dichloropropan-2-ol

Chemical Identifiers

InChI
InChI=1S/C3H6Cl2O/c4-1-3(6)2-5/h3,6H,1-2H2
InChI Key
DEWLEGDTCGBNGU-UHFFFAOYSA-N

Overview

1,3-Dichloropropan-2-ol (CAS 96-23-1) is a chlorinated organic compound with the molecular formula C3H6Cl2O and significant industrial applications despite its hazardous properties. This dichlorinated alcohol represents an important intermediate in chemical synthesis and industrial processes, characterized by its molecular weight of 128.98 g/mol. The compound features two chlorine atoms attached to the terminal carbon positions of a three-carbon chain, with a hydroxyl group positioned on the central carbon atom. This structural arrangement gives 1,3-dichloropropan-2-ol its distinctive chemical reactivity and utility in various manufacturing applications. The substance is classified under EC number 202-491-9 and falls within ADR transport class 6.1, reflecting its toxic nature. Safety considerations are paramount when handling this compound, as it carries serious health hazard classifications including Carc. 1B and acute toxicity ratings. The presence of GHS08 and GHS06 pictograms, along with the "Danger" signal word, emphasizes the need for stringent safety protocols during storage, handling, and transportation. Industrial applications of 1,3-dichloropropan-2-ol include its use as a chemical intermediate in the synthesis of various organic compounds and as a solvent in specialized applications. The compound also serves in the production of certain polymers and resins. Like other halogenated compounds such as chloromethylbenzene, it requires careful handling due to its reactive nature and potential health impacts. Manufacturing facilities utilizing this compound typically implement comprehensive safety measures and environmental controls. The substance's reactivity profile makes it valuable for specific synthetic pathways while demanding expertise in hazardous material management. OYSI maintains availability of 1,3-dichloropropan-2-ol for qualified industrial customers with appropriate handling capabilities and regulatory compliance.

Safety & Classification

Danger
Classification:

Carc. 1B; Acute Tox. 4 *; Acute Tox. 3 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2750
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name1,3-Dichlorpropan-2-ol
Marine PollutantNo

Frequently Asked Questions

What is 1,3-dichloropropan-2-ol?

1,3-dichloropropan-2-ol is an organochlorine compound with the molecular formula C3H6Cl2O and CAS number 96-23-1. This chemical substance has a molecular weight of 128.98 g/mol and belongs to the chlorinated alcohol family. It is classified as a Category 1B carcinogen and acute toxicity substance, making it a highly regulated chemical requiring strict handling protocols and safety measures in industrial applications.

What are the physicochemical properties of 1,3-dichloropropan-2-ol?

1,3-dichloropropan-2-ol is a colorless to pale yellow liquid at room temperature with a characteristic chlorinated solvent odor. It is moderately soluble in water and miscible with most organic solvents including alcohols and ethers. The compound has a boiling point around 174°C and a density higher than water. Its chlorinated structure makes it relatively stable under normal conditions but susceptible to hydrolysis in alkaline environments.

What is 1,3-dichloropropan-2-ol used for?

1,3-dichloropropan-2-ol is primarily used as an intermediate in chemical synthesis and pharmaceutical manufacturing. It serves as a building block for producing various organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. Due to its carcinogenic classification, its applications are strictly regulated and limited to controlled industrial processes where appropriate safety measures can be implemented to protect workers and the environment.

How to handle 1,3-dichloropropan-2-ol safely?

1,3-dichloropropan-2-ol requires maximum safety precautions due to its carcinogenic and toxic properties. Essential PPE includes chemical-resistant gloves, full face protection, and impermeable protective clothing. Work must be conducted in well-ventilated areas or under fume extraction systems. Avoid skin contact, inhalation, and ingestion completely. Regular health monitoring of exposed workers is mandatory, and all handling procedures must comply with occupational safety regulations.

How to store 1,3-dichloropropan-2-ol correctly?

1,3-dichloropropan-2-ol must be stored in tightly sealed, compatible containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Storage areas should be equipped with appropriate containment systems and restricted access due to the substance's carcinogenic nature. Keep away from incompatible materials such as strong bases and oxidizing agents. Temperature should be maintained below 25°C to ensure stability and prevent vapor formation.

What to do in case of contact with 1,3-dichloropropan-2-ol?

Immediate action is critical upon contact with 1,3-dichloropropan-2-ol. For skin contact, remove contaminated clothing and rinse affected area with copious amounts of water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with water for 15 minutes while holding eyelids open. Seek immediate medical attention in all cases and provide safety data sheet to medical personnel. Never induce vomiting if ingested.

How to dispose of 1,3-dichloropropan-2-ol appropriately?

1,3-dichloropropan-2-ol must be disposed of as hazardous waste through licensed waste management facilities specialized in handling carcinogenic substances. Incineration at high temperatures in approved facilities is typically required. Empty containers must also be treated as hazardous waste. All disposal activities must comply with local and European waste regulations, including proper documentation and tracking. Never discharge into sewers, soil, or water bodies under any circumstances.

How to transport 1,3-dichloropropan-2-ol?

1,3-dichloropropan-2-ol is classified under ADR Class 6.1 (toxic substances), Packing Group II, indicating significant transport hazards. It must be packaged in UN-approved containers with appropriate labeling including GHS08 and GHS06 pictograms and 'Danger' signal word. Transport requires proper documentation, emergency response information, and compliance with ADR regulations. Only certified carriers experienced in handling toxic chemicals should transport this substance.

Is 1,3-dichloropropan-2-ol subject to specific regulations?

1,3-dichloropropan-2-ol is subject to extensive European regulations under REACH and CLP due to its carcinogenic classification (Carc. 1B). Registration requirements, exposure scenarios, and risk management measures must be strictly followed. The substance may be subject to authorization procedures and workplace exposure limits. Companies must implement comprehensive risk assessment and management protocols. Regular reporting and monitoring obligations apply to all users and distributors within the supply chain.

Where to buy 1,3-dichloropropan-2-ol in Europe?

1,3-dichloropropan-2-ol is available through OYSI, a specialized European distributor of technical chemicals with expertise in handling regulated substances. As a carcinogenic material, purchase requires proper authorization, documentation of intended use, and compliance with regulatory requirements. OYSI provides comprehensive support including safety documentation, regulatory guidance, and proper packaging. Contact OYSI directly to discuss availability, regulatory compliance, and specific application requirements for this controlled substance.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.