1,3-dichloropropan-2-ol
C3H6Cl2O
Consulting for 1,3-dichloropropan-2-ol
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Identification
- CAS Number
- 96-23-1
- EC Number
- 202-491-9
- UN Number
- 2750
- Index Number
- 602-064-00-0
- PubChem CID
- 7289
Physical-chemical properties
- Molecular Formula
- C3H6Cl2O
- Molar Mass
- 128.98 g/mol
- IUPAC Name
- 1,3-dichloropropan-2-ol
Chemical Identifiers
- InChI
- InChI=1S/C3H6Cl2O/c4-1-3(6)2-5/h3,6H,1-2H2
- InChI Key
- DEWLEGDTCGBNGU-UHFFFAOYSA-N
Overview
1,3-dichloropropan-2-ol (CAS 96-23-1) is a chlorinated organic alcohol compound with significant industrial applications and notable toxicological properties. This halogenated secondary alcohol represents an important intermediate in chemical synthesis, featuring two chlorine atoms positioned at the terminal carbon atoms of a three-carbon chain with a hydroxyl group at the central position. The compound's molecular structure (C3H6Cl2O) with a molecular weight of 128.98 g/mol makes it a versatile building block in organic chemistry applications. 1,3-dichloropropan-2-ol exhibits significant safety considerations due to its classification as a Category 1B carcinogen and acute toxicity properties, requiring careful handling protocols and appropriate safety measures. The substance falls under ADR transport class 6.1, reflecting its toxic nature, and displays GHS08 and GHS06 pictograms indicating both health hazards and acute toxicity risks. Professional users must implement strict safety protocols including proper ventilation, personal protective equipment, and containment procedures. The compound finds primary applications in pharmaceutical intermediate synthesis, specialty chemical manufacturing, and as a reagent in organic synthesis processes. Its reactivity profile makes it valuable for producing various derivatives and complex molecules in controlled industrial environments. Unlike simpler chlorinated compounds such as chloromethylbenzene, 1,3-dichloropropan-2-ol offers unique bifunctional reactivity through its dual chlorine substitution pattern. Industrial users typically employ this substance in closed-system processes due to its hazardous classification, ensuring minimal exposure risks while maximizing synthetic utility. The compound's chemical properties enable selective reactions that are difficult to achieve with alternative reagents. OYSI maintains reliable supply chains for 1,3-dichloropropan-2-ol, supporting European industrial customers with technical-grade material suitable for specialized chemical synthesis applications.
Safety & Classification
Carc. 1B; Acute Tox. 4 *; Acute Tox. 3 *
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2750 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | 1,3-Dichlorpropan-2-ol |
| Marine Pollutant | No |
Frequently Asked Questions
What is 1,3-dichloropropan-2-ol?
1,3-dichloropropan-2-ol is an organochlorine compound with the molecular formula C3H6Cl2O and CAS number 96-23-1. This chemical substance has a molecular weight of 128.98 g/mol and belongs to the category of chlorinated alcohols. It is classified as a carcinogenic substance (Category 1B) and exhibits acute toxicity properties, requiring careful handling and strict safety protocols in industrial applications.
What are the physicochemical properties of 1,3-dichloropropan-2-ol?
1,3-dichloropropan-2-ol is a colorless to pale yellow liquid at room temperature with a characteristic chlorinated solvent odor. The compound is moderately soluble in water and highly soluble in organic solvents such as alcohols and ethers. It has a boiling point around 174°C and exhibits typical properties of chlorinated organic compounds, including chemical stability under normal conditions but potential for decomposition under extreme heat.
What is 1,3-dichloropropan-2-ol used for?
1,3-dichloropropan-2-ol is primarily used as an intermediate in chemical synthesis and pharmaceutical manufacturing. It serves as a building block for producing various organic compounds and can be utilized in specialty chemical applications. Due to its carcinogenic classification, its use is strictly regulated and limited to controlled industrial processes where appropriate safety measures and containment systems are implemented to protect workers and the environment.
How to handle 1,3-dichloropropan-2-ol safely?
1,3-dichloropropan-2-ol requires strict safety protocols including chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Workers must wear appropriate personal protective equipment and avoid skin contact, inhalation, or ingestion due to its carcinogenic and acute toxicity properties. All handling operations should be conducted in fume hoods or controlled environments with proper emergency procedures and safety training in place.
How to store 1,3-dichloropropan-2-ol correctly?
1,3-dichloropropan-2-ol must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources, ignition sources, and incompatible materials. Storage areas should be equipped with appropriate containment systems and emergency response equipment. The substance should be kept away from strong oxidizing agents and bases, and storage facilities must comply with local regulations for carcinogenic substances and toxic materials.
What to do in case of contact with 1,3-dichloropropan-2-ol?
Immediate decontamination is essential following contact with 1,3-dichloropropan-2-ol. For skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes. If inhaled, move the person to fresh air immediately. Seek medical attention promptly in all cases and provide medical personnel with the safety data sheet.
How to dispose of 1,3-dichloropropan-2-ol appropriately?
1,3-dichloropropan-2-ol must be disposed of as hazardous waste through licensed waste management companies specializing in toxic and carcinogenic substances. The disposal process must comply with local and EU regulations for hazardous waste, including proper classification, labeling, and documentation. Incineration at high temperatures in approved facilities is typically required, and discharge to sewers, soil, or waterways is strictly prohibited under environmental protection laws.
How to transport 1,3-dichloropropan-2-ol?
1,3-dichloropropan-2-ol is classified under ADR Class 6.1 (Toxic substances), Packing Group II, indicating significant toxicity requiring special transport precautions. The substance must be packaged in UN-approved containers with proper hazard labels and documentation. Transportation requires compliance with dangerous goods regulations, including driver certification, vehicle marking, and emergency response procedures. Professional logistics companies experienced in hazardous materials transport should handle shipments.
Is 1,3-dichloropropan-2-ol subject to specific regulations?
1,3-dichloropropan-2-ol is subject to strict European regulations under REACH and CLP classifications due to its carcinogenic properties (Category 1B) and acute toxicity. The substance requires comprehensive risk assessments, exposure control measures, and worker protection protocols. Companies handling this chemical must comply with occupational health regulations, environmental protection laws, and may need specific authorizations or notifications depending on usage quantities and applications in their operations.
Where to buy 1,3-dichloropropan-2-ol in Europe?
1,3-dichloropropan-2-ol is available through specialized chemical distributors like OYSI, which provides technical-grade chemicals to European markets. Due to its hazardous classification, purchases typically require proper business credentials, safety documentation, and compliance with regulatory requirements. OYSI can provide technical support, safety data sheets, and ensure proper packaging and transportation according to ADR regulations for professional customers with legitimate industrial applications.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.