1,2-diethoxyethane

C6H14O2

CAS629-14-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
629-14-1
EC Number
211-076-1
UN Number
1153
Index Number
603-208-00-5
PubChem CID
12375

Physical-chemical properties

Molecular Formula
C6H14O2
Molar Mass
118.17 g/mol
IUPAC Name
1,2-diethoxyethane

Chemical Identifiers

InChI
InChI=1S/C6H14O2/c1-3-7-5-6-8-4-2/h3-6H2,1-2H3
InChI Key
LZDKZFUFMNSQCJ-UHFFFAOYSA-N

Overview

1,2-Diethoxyethane (CAS 629-14-1) is an organic ether solvent with excellent solvating properties and moderate volatility. This diethyl ether derivative serves as a versatile aprotic solvent in various industrial chemical processes. With its molecular formula C6H14O2 and molecular weight of 118.17 g/mol, 1,2-diethoxyethane exhibits characteristic ether properties while maintaining enhanced stability compared to simpler ether compounds. The substance belongs to the glycol ether family, sharing certain solvent characteristics with other industrial solvents like ethylbenzene, though with distinct polarity and boiling point properties. The chemical structure features two ethoxy groups attached to an ethylene backbone, providing both hydrophilic and lipophilic characteristics that make it particularly effective for dissolving a wide range of organic compounds. This dual nature enables excellent miscibility with both polar and nonpolar substances, making it valuable in formulation chemistry. Safety considerations are paramount when handling 1,2-diethoxyethane, as it carries significant hazard classifications including Flammable Liquid Category 2, Reproductive Toxicity Category 1A, and Eye Irritation Category 2. The substance requires careful handling protocols, appropriate personal protective equipment, and adherence to ADR Class 3 transportation regulations. Storage areas must maintain proper ventilation and fire prevention measures due to its flammable nature. Industrial applications include use as a reaction medium in pharmaceutical synthesis, as a component in specialty coatings formulations, and as an extraction solvent in chemical processing operations. Its unique solvating properties make it particularly suitable for processes requiring selective dissolution or purification steps. OYSI maintains reliable supply chains for 1,2-diethoxyethane to serve European industrial customers requiring this specialized solvent.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Repr. 1A; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1153
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameEthylenglycoldiethylether, 23 °C <= Flp. <= 60 °C
Marine PollutantNo

Frequently Asked Questions

What is 1,2-diethoxyethane?

1,2-diethoxyethane is an organic chemical compound with the molecular formula C6H14O2 and CAS number 629-14-1. This ether derivative has a molecular weight of 118.17 g/mol and belongs to the glycol ether family. It is classified as a flammable liquid with reproductive toxicity and eye irritation properties, requiring careful handling in industrial applications.

What are the physicochemical properties of 1,2-diethoxyethane?

1,2-diethoxyethane is a colorless liquid at room temperature with a characteristic ether-like odor. As a glycol ether, it exhibits good solubility in both polar and non-polar solvents, making it an effective solvent system. The compound has moderate volatility and is miscible with many organic solvents while showing limited water solubility.

What is 1,2-diethoxyethane used for?

1,2-diethoxyethane serves primarily as a specialized solvent in chemical synthesis and industrial processes. Its dual ether functionality makes it valuable for dissolving various organic compounds and as a reaction medium. It finds applications in pharmaceutical intermediates, specialty chemical manufacturing, and research laboratories where selective solvation properties are required.

How to handle 1,2-diethoxyethane safely?

1,2-diethoxyethane requires strict safety protocols due to its flammable and reproductive toxic properties. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work in well-ventilated areas away from ignition sources, and implement fire prevention measures. Pregnant workers should avoid exposure due to reproductive toxicity concerns (Repr. 1A classification).

How to store 1,2-diethoxyethane correctly?

1,2-diethoxyethane must be stored in cool, dry, well-ventilated areas away from heat sources and ignition points. Use appropriate containers resistant to ether compounds and ensure proper grounding to prevent static electricity buildup. Keep containers tightly sealed and store separately from oxidizing agents and incompatible materials. Maintain storage temperature below flash point.

What to do in case of contact with 1,2-diethoxyethane?

In case of skin contact with 1,2-diethoxyethane, immediately remove contaminated clothing and wash affected area thoroughly with soap and water. For eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention due to eye irritation potential. If inhaled, move to fresh air immediately and seek medical attention if respiratory symptoms develop.

How to dispose of 1,2-diethoxyethane appropriately?

1,2-diethoxyethane disposal must comply with local and European waste regulations as hazardous chemical waste. Contact authorized waste disposal companies specializing in flammable and toxic solvents. Never discharge into sewers or environment. Waste containers should be properly labeled and stored in designated areas until collection. Consider recovery or recycling options where technically and economically feasible.

How to transport 1,2-diethoxyethane?

1,2-diethoxyethane is classified under ADR Class 3 (flammable liquids), Packing Group III for transportation. Shipments must use appropriate packaging meeting UN specification requirements and proper hazard labeling including flammable liquid markings. Transport vehicles require ADR compliance, and drivers need appropriate training certification. Ensure proper documentation accompanies all shipments across European borders.

Is 1,2-diethoxyethane subject to specific regulations?

1,2-diethoxyethane falls under various European regulations including CLP classification requiring GHS02, GHS08, and GHS07 pictograms with 'Danger' signal word. REACH registration applies for quantities above one tonne annually. The substance is not currently listed as SVHC but requires reproductive toxicity labeling and safety data sheet provision to downstream users.

Where to buy 1,2-diethoxyethane in Europe?

1,2-diethoxyethane is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with full regulatory compliance, appropriate packaging, and technical support. As a professional chemical distributor, OYSI ensures proper documentation, safety data sheets, and adherence to European chemical regulations for industrial customers across Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.