1,2-dibromo-3-chloropropane

C3H5Br2Cl

CAS96-12-8
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
96-12-8
EC Number
202-479-3
UN Number
2872
Index Number
602-021-00-6
PubChem CID
7280

Physical-chemical properties

Molecular Formula
C3H5Br2Cl
Molar Mass
236.33 g/mol
IUPAC Name
1,2-dibromo-3-chloropropane

Chemical Identifiers

InChI
InChI=1S/C3H5Br2Cl/c4-1-3(5)2-6/h3H,1-2H2
InChI Key
WBEJYOJJBDISQU-UHFFFAOYSA-N

Overview

1,2-dibromo-3-chloropropane (CAS 96-12-8) is a halogenated alkane compound characterized by high toxicity and significant environmental persistence. This organohalogen compound represents a critical example of polyhalogenated hydrocarbons used in specialized industrial applications. With its molecular formula C3H5Br2Cl and molecular weight of 236.33 g/mol, 1,2-dibromo-3-chloropropane exhibits the complex reactivity patterns typical of mixed halogenated compounds. The presence of both bromine and chlorine atoms on the three-carbon chain creates unique chemical properties that distinguish it from simpler halogenated compounds like chloromethylbenzene, which contains only chlorine substitution on an aromatic system. The compound is classified under multiple serious hazard categories, including carcinogenicity (Category 1B), mutagenicity (Category 1B), and reproductive toxicity (Category 1A), reflecting its potential for causing cancer, genetic damage, and reproductive harm. Additional classifications include acute toxicity (Category 3), specific target organ toxicity following repeated exposure (Category 2), and chronic aquatic toxicity (Category 3). These classifications necessitate extreme caution during handling, with mandatory use of appropriate personal protective equipment and engineered safety controls. Industrial applications of 1,2-dibromo-3-chloropropane primarily include use as an intermediate in organic synthesis, particularly in the production of specialized pharmaceutical compounds and advanced materials. It also finds application in certain niche chemical manufacturing processes where its unique halogenation pattern provides specific reactivity advantages. The compound serves as a valuable building block in the synthesis of complex molecules requiring precise halogen positioning. OYSI maintains availability of 1,2-dibromo-3-chloropropane for qualified industrial customers with appropriate handling capabilities and regulatory compliance frameworks.

Safety & Classification

Danger
Classification:

Carc. 1B; Muta. 1B; Repr. 1A; Acute Tox. 3 *; STOT RE 2 *; Aquatic Chronic 3

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H340

May cause genetic defects.

H301

Toxic if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H412

Harmful to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2872
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping Name1,2-Dibrom-3-chlorpropan
Marine PollutantNo

Frequently Asked Questions

What is 1,2-dibromo-3-chloropropane?

1,2-dibromo-3-chloropropane is a halogenated organic compound with the molecular formula C3H5Br2Cl and CAS number 96-12-8. This chemical substance has a molecular weight of 236.33 g/mol and belongs to the family of organohalogen compounds. It is classified as extremely hazardous due to its carcinogenic, mutagenic, and reproductive toxicity properties, requiring strict handling protocols and regulatory compliance in industrial applications.

What are the physicochemical properties of 1,2-dibromo-3-chloropropane?

1,2-dibromo-3-chloropropane is typically a colorless to pale yellow liquid at room temperature with a characteristic sweet odor. The compound has limited water solubility but dissolves well in organic solvents such as alcohols, ethers, and chlorinated hydrocarbons. Its high halogen content contributes to its relatively high density and boiling point compared to similar non-halogenated compounds, making it stable under normal storage conditions.

What is 1,2-dibromo-3-chloropropane used for?

1,2-dibromo-3-chloropropane is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. Due to its severe health hazards and regulatory restrictions, its applications are limited to specialized industrial processes where strict safety protocols can be implemented. It may serve as a building block for producing other halogenated compounds or as a reagent in specific chemical transformations under controlled laboratory or industrial conditions.

How to handle 1,2-dibromo-3-chloropropane safely?

1,2-dibromo-3-chloropropane must be handled with extreme caution using full personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Given its carcinogenic and mutagenic properties, minimize skin contact and ensure proper training for all personnel. Emergency shower and eyewash stations should be readily accessible during handling operations.

How to store 1,2-dibromo-3-chloropropane correctly?

1,2-dibromo-3-chloropropane should be stored in tightly sealed, chemically compatible containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Storage areas must be equipped with appropriate containment systems and restricted access due to the substance's high toxicity. Keep containers upright and properly labeled according to GHS requirements, and maintain storage temperatures within recommended ranges to ensure product stability and safety.

What to do in case of contact with 1,2-dibromo-3-chloropropane?

Immediate action is required upon contact with 1,2-dibromo-3-chloropropane due to its high toxicity. For skin contact, remove contaminated clothing and flush affected areas with plenty of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move the person to fresh air immediately. For all exposure routes, contact emergency medical services promptly and provide the safety data sheet to healthcare professionals.

How to dispose of 1,2-dibromo-3-chloropropane appropriately?

1,2-dibromo-3-chloropropane must be disposed of as hazardous waste through licensed waste management companies specializing in toxic chemical disposal. Due to its classification as carcinogenic and mutagenic, it requires special handling procedures and cannot be disposed of through normal waste streams. Consult local environmental regulations and waste disposal authorities for specific requirements. All disposal activities must be documented and comply with European waste management directives and national regulations.

How to transport 1,2-dibromo-3-chloropropane?

1,2-dibromo-3-chloropropane is classified under ADR as Class 6.1 (toxic substances), Packing Group III for transportation purposes. Packages must display appropriate hazard labels including GHS06 and GHS08 pictograms with 'Danger' signal word. Transportation requires proper documentation, trained personnel, and compliance with dangerous goods regulations. Vehicles must carry appropriate emergency equipment and follow prescribed routes. Only certified carriers experienced in handling toxic chemicals should transport this substance.

Is 1,2-dibromo-3-chloropropane subject to specific regulations?

1,2-dibromo-3-chloropropane is subject to strict regulatory oversight under European REACH and CLP regulations due to its severe health hazards. The substance is classified as Carcinogenic 1B, Mutagenic 1B, and Reproductive Toxicant 1A, requiring comprehensive risk assessments and safety measures. Users must comply with occupational exposure limits, worker protection requirements, and environmental release restrictions. Special authorization or restrictions may apply for certain uses under European chemical legislation.

Where to buy 1,2-dibromo-3-chloropropane in Europe?

1,2-dibromo-3-chloropropane is available through specialized chemical distributors like OYSI, which serves the European market with technical-grade chemicals. Due to its hazardous classification and regulatory restrictions, purchases require proper documentation, end-use declarations, and compliance verification. OYSI provides comprehensive support including safety data sheets, regulatory guidance, and proper packaging for safe delivery. Contact OYSI directly to discuss specific requirements and availability for your industrial applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.