1,1'-biphenyl

C12H10

CAS92-52-4
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
92-52-4
EC Number
202-163-5
UN Number
3077
Index Number
601-042-00-8
PubChem CID
7095

Physical-chemical properties

Molecular Formula
C12H10
Molar Mass
154.21 g/mol
IUPAC Name
1,1'-biphenyl

Chemical Identifiers

InChI
InChI=1S/C12H10/c1-3-7-11(8-4-1)12-9-5-2-6-10-12/h1-10H
InChI Key
ZUOUZKKEUPVFJK-UHFFFAOYSA-N

Overview

1,1'-biphenyl (CAS 92-52-4) is an aromatic hydrocarbon compound consisting of two benzene rings connected by a single carbon-carbon bond, widely used as an intermediate in organic synthesis. This crystalline organic compound, also known simply as biphenyl, represents a fundamental structure in aromatic chemistry with significant industrial relevance. With the molecular formula C12H10 and a molar mass of 154.21 g/mol, biphenyl serves as a key building block for numerous chemical syntheses and specialized applications across various industries. The compound exhibits notable physical and chemical properties that make it valuable for technical applications. As a stable aromatic system, biphenyl demonstrates good thermal stability and resistance to oxidation under normal conditions. However, safety considerations are paramount when handling this substance, as it carries multiple hazard classifications including skin and eye irritation (Skin Irrit. 2, Eye Irrit. 2), specific target organ toxicity (STOT SE 3), and significant aquatic toxicity (Aquatic Acute 1, Aquatic Chronic 1). The GHS07 and GHS09 pictograms with a "Warning" signal word reflect these safety concerns, and proper handling procedures must be implemented during storage, transport, and use. Industrial applications of biphenyl span several sectors, including its use as a heat transfer medium in specialized thermal systems, as an intermediate in the production of various organic compounds, and in the synthesis of advanced materials. The compound's structural similarity to other chemical intermediates like 6-methylheptyl prop-2-enoate makes it particularly valuable in comparative synthetic pathways. Given its classification under ADR Class 9 (miscellaneous dangerous goods), biphenyl requires specialized logistics and handling expertise. OYSI provides reliable access to high-quality 1,1'-biphenyl for European technical applications, ensuring proper documentation and safety compliance for industrial customers.

Safety & Classification

Warning
Classification:

STOT SE 3; Skin Irrit. 2; Eye Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameDiphenyl, fest
Marine PollutantNo

Frequently Asked Questions

What is 1,1'-biphenyl?

1,1'-biphenyl is an aromatic hydrocarbon compound consisting of two benzene rings connected by a single bond. With the molecular formula C12H10 and CAS number 92-52-4, it has a molecular weight of 154.21 g/mol. This organic compound appears as white to pale yellow crystals or flakes with a distinctive pleasant aromatic odor. It is classified as a polycyclic aromatic hydrocarbon and serves as an important intermediate in various chemical processes and industrial applications.

What are the physicochemical properties of 1,1'-biphenyl?

1,1'-biphenyl is a solid crystalline substance at room temperature, typically appearing as white to pale yellow crystals or flakes. It has a characteristic pleasant aromatic odor and is practically insoluble in water but readily soluble in organic solvents such as alcohol, ether, and benzene. The compound has a melting point around 69-70°C and a boiling point of approximately 255°C. It is stable under normal conditions but may undergo oxidation when exposed to strong oxidizing agents.

What is 1,1'-biphenyl used for?

1,1'-biphenyl is primarily used as an intermediate in the synthesis of various chemicals and pharmaceuticals. It serves as a heat transfer medium in industrial processes due to its thermal stability. The compound is also utilized in the production of dyes, optical brighteners, and as a fungicide for citrus fruits. Additionally, it finds applications in the manufacture of polychlorinated biphenyls (PCBs) precursors and as a solvent in certain industrial processes, though environmental concerns have limited some of these uses.

How to handle 1,1'-biphenyl safely?

1,1'-biphenyl requires careful handling due to its skin and eye irritation potential and specific target organ toxicity. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation to prevent inhalation of vapors or dust. Avoid direct skin and eye contact, and do not eat, drink, or smoke while handling. Work in well-ventilated areas or under fume hoods, and wash hands thoroughly after handling to prevent accidental exposure.

How to store 1,1'-biphenyl correctly?

1,1'-biphenyl should be stored in a cool, dry, well-ventilated area away from heat sources, ignition sources, and direct sunlight. Keep containers tightly closed and store in original packaging or compatible containers. Maintain storage temperature below 25°C to prevent sublimation. Separate from strong oxidizing agents and incompatible materials. Ensure storage areas are equipped with appropriate spill containment measures and comply with local fire safety regulations. Regular inspection of containers for damage or deterioration is recommended.

What to do in case of contact with 1,1'-biphenyl?

In case of skin contact with 1,1'-biphenyl, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes while holding eyelids open. If inhaled, move the person to fresh air and keep them at rest. If swallowed, do not induce vomiting; rinse mouth with water. Seek medical attention if irritation persists or symptoms develop after any type of exposure.

How to dispose of 1,1'-biphenyl appropriately?

1,1'-biphenyl must be disposed of as hazardous waste in accordance with local, national, and EU regulations due to its environmental hazard classification. Contact licensed waste disposal companies for proper handling and treatment. Incineration at authorized high-temperature facilities is typically the preferred disposal method. Never discharge into drains, waterways, or the environment as it poses risks to aquatic life. Empty containers should also be treated as hazardous waste unless properly cleaned and decontaminated according to regulatory requirements.

How to transport 1,1'-biphenyl?

1,1'-biphenyl is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation purposes. It requires appropriate hazardous goods packaging, labeling, and documentation during transport. Vehicles must carry proper placards and emergency response information. Transport should be conducted by trained personnel familiar with dangerous goods regulations. Ensure packages are properly secured to prevent damage during transit and that emergency response procedures are readily available in case of incidents during transportation.

Is 1,1'-biphenyl subject to specific regulations?

1,1'-biphenyl is subject to various European regulations including REACH registration requirements and CLP classification as STOT SE 3, Skin Irritant 2, Eye Irritant 2, and Aquatic hazard categories. However, it is not currently listed as an SVHC (Substance of Very High Concern). Companies handling this substance must comply with occupational safety regulations, environmental protection laws, and proper waste disposal requirements. Regular safety data sheet updates and risk assessments are mandatory for commercial users and distributors.

Where to buy 1,1'-biphenyl in Europe?

1,1'-biphenyl is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI can provide this substance with proper documentation, safety data sheets, and regulatory compliance support. For procurement, contact OYSI directly to discuss your specific requirements, quantities, and delivery options. Other authorized chemical distributors and manufacturers may also supply this substance, but ensure they provide proper REACH registration documentation and meet all regulatory requirements for safe handling and transport.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.