Cyclopropane
C3H6
cyclopropane
Consulting for Cyclopropane
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Identification
- CAS Number
- 75-19-4
- EC Number
- 200-847-8
- UN Number
- 1027
- Index Number
- 601-016-00-6
- PubChem CID
- 6351
Physical-chemical properties
- Molecular Formula
- C3H6
- Molar Mass
- 42.08 g/mol
- IUPAC Name
- cyclopropane
Chemical Identifiers
- InChI
- InChI=1S/C3H6/c1-2-3-1/h1-3H2
- InChI Key
- LVZWSLJZHVFIQJ-UHFFFAOYSA-N
Overview
Cyclopropane (CAS 75-19-4) is a three-membered saturated cyclic hydrocarbon with high ring strain and flammable gas properties at room temperature. This smallest cycloalkane represents a unique class of organic compounds characterized by exceptional molecular stability despite its inherent ring strain. With the molecular formula C3H6 and a molar mass of 42.08 g/mol, cyclopropane exists as a colorless gas under standard conditions, requiring specialized handling procedures due to its classification as a flammable gas (Flam. Gas 1) and pressurized gas (Press. Gas) under GHS regulations. The compound's distinctive triangular structure creates significant angle strain, as the C-C-C bond angles of 60° deviate substantially from the ideal tetrahedral angle of 109.5°. This structural characteristic makes cyclopropane considerably more reactive than its linear counterpart prop-1-ene, despite sharing the same molecular formula. Unlike methoxymethane or methoxyethene, cyclopropane contains no heteroatoms, consisting entirely of carbon and hydrogen in a highly strained ring configuration. From a safety perspective, cyclopropane requires careful handling due to its flammable nature and pressurized state, as indicated by the GHS02 and GHS04 pictograms. The substance falls under ADR Class 2 for transportation, necessitating appropriate containment and safety protocols during storage and handling operations. Industrial applications of cyclopropane include its use as a synthetic intermediate in organic chemistry, particularly in cyclopropanation reactions and as a building block for more complex cyclic compounds. The pharmaceutical industry utilizes cyclopropane derivatives in drug synthesis, while research laboratories employ it for mechanistic studies of strained ring systems. OYSI maintains reliable supply chains for cyclopropane, ensuring consistent availability for European industrial customers requiring this specialized cyclic hydrocarbon.
Safety & Classification
Flam. Gas 1; Press. Gas
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Extremely flammable gas.
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Transport (ADR)
| UN Number | 1027 |
| ADR Class | 2 |
| Packing Group | |
| Tunnel Code | B/D |
| Proper Shipping Name | Cyclopropan, unter Druck verflüssigt |
| Marine Pollutant | No |
Frequently Asked Questions
What is cyclopropane?
Cyclopropane is a highly flammable cyclic hydrocarbon with the molecular formula C3H6 and CAS number 75-19-4. This three-membered ring compound has a molecular weight of 42.08 g/mol and exists as a colorless gas under normal conditions. Due to its significant ring strain, cyclopropane is highly reactive and poses serious fire and explosion hazards, requiring careful handling and storage procedures.
What are the physicochemical properties of cyclopropane?
Cyclopropane is a colorless gas at room temperature with a characteristic sweet odor. It has a boiling point of -32.8°C and is moderately soluble in water but highly soluble in organic solvents. The compound exhibits high ring strain due to its three-membered cyclic structure, making it thermodynamically unstable and prone to ring-opening reactions under various conditions.
What is cyclopropane used for?
Cyclopropane is primarily used as an anesthetic agent in medical applications, though its use has declined due to safety concerns. It serves as an intermediate in organic synthesis for manufacturing pharmaceuticals and fine chemicals. The compound is also utilized in research applications for studying cyclic hydrocarbon chemistry and as a precursor for various chemical transformations in laboratory settings.
How to handle cyclopropane safely?
Cyclopropane requires extreme caution due to its flammable gas classification (Flam. Gas 1). Always use appropriate personal protective equipment including safety goggles, flame-resistant clothing, and work in well-ventilated areas or fume hoods. Eliminate all ignition sources, use explosion-proof equipment, and ensure proper grounding of containers. Never smoke or use open flames near this substance, and maintain emergency procedures for gas leaks.
How to store cyclopropane correctly?
Cyclopropane must be stored in pressurized gas cylinders in cool, dry, well-ventilated areas away from heat sources and ignition points. Keep containers upright and secured, away from incompatible materials such as oxidizing agents. Storage areas should be equipped with gas detection systems and emergency ventilation. Maintain temperatures below 40°C and protect cylinders from physical damage and direct sunlight.
What to do in case of contact with cyclopropane?
Cyclopropane exposure primarily occurs through inhalation, causing dizziness, drowsiness, or unconsciousness at high concentrations. Immediately move the affected person to fresh air and keep them at rest. If breathing difficulties occur, provide oxygen and seek immediate medical attention. In case of skin contact with liquid cyclopropane, remove contaminated clothing and flush with water. Contact emergency services for serious exposures.
How to dispose of cyclopropane appropriately?
Cyclopropane disposal must comply with local and European waste regulations as a hazardous substance. Never release the gas into the atmosphere or sewage systems. Contact licensed waste disposal companies specializing in flammable gas treatment. Small quantities can be carefully vented in controlled environments with proper safety measures, but larger amounts require professional disposal through authorized chemical waste management facilities.
How to transport cyclopropane?
Cyclopropane is classified as ADR Class 2 (gases) for transportation purposes. It must be shipped in approved pressure vessels with proper labeling including GHS02 and GHS04 pictograms and "Danger" signal word. Vehicles must be equipped with appropriate safety equipment, and drivers require hazardous materials certification. Transport should avoid extreme temperatures and ensure proper securing of gas cylinders.
Is cyclopropane subject to specific regulations?
Cyclopropane is regulated under European CLP regulation with mandatory classification as Flam. Gas 1 and Press. Gas, requiring GHS02 and GHS04 pictograms. It falls under REACH registration requirements for commercial use. The substance is not currently listed as SVHC (Substance of Very High Concern). Users must comply with workplace safety regulations and maintain proper safety data sheets for handling and storage.
Where to buy cyclopropane in Europe?
Cyclopropane is available through specialized chemical distributors across Europe, including OYSI, which supplies various grades for industrial and research applications. Due to its hazardous nature, purchases typically require proper licensing and safety certifications. Contact OYSI's technical team to discuss specific requirements, quantities, and delivery arrangements while ensuring compliance with local regulations for handling flammable gases.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.