1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole

C14H14Cl2N2O

CAS35554-44-0
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
35554-44-0
EC Number
252-615-0
UN Number
2761
Index Number
613-042-00-5
PubChem CID
37175

Physical-chemical properties

Molecular Formula
C14H14Cl2N2O
Molar Mass
297.20 g/mol
IUPAC Name
1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole

Chemical Identifiers

InChI
InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2
InChI Key
PZBPKYOVPCNPJY-UHFFFAOYSA-N

Overview

1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole (CAS 35554-44-0) is an organochlorine imidazole derivative with antifungal properties and significant toxicological considerations. This dichlorophenyl imidazole compound represents a specialized chemical intermediate with a molecular weight of 297.2 g/mol and formula C14H14Cl2N2O. The substance features a distinctive structure combining a dichlorophenyl ring system with an imidazole moiety connected through a prop-2-enoxyethyl linker, conferring specific chemical reactivity and biological activity profiles. Safety classification under GHS requires careful handling protocols due to its Danger signal word designation. The compound exhibits multiple hazard classifications including suspected carcinogenicity (Carc. 2), acute toxicity (categories 3 and 4), severe eye damage potential (Eye Dam. 1), and long-term aquatic toxicity (Aquatic Chronic 1). Transportation falls under ADR Class 6.1, reflecting its toxic nature and requiring appropriate shipping documentation and packaging. The chemical structure relationship to other halogenated compounds like 2,2-dibromo-2-cyanoacetamide demonstrates the broader family of halogen-containing industrial intermediates, though each maintains distinct reactivity patterns and applications. Industrial applications primarily focus on pharmaceutical intermediate synthesis, agrochemical production, and specialized research applications where the imidazole functionality provides essential chemical building blocks. Processing facilities must implement comprehensive safety measures including appropriate ventilation systems, personal protective equipment protocols, and environmental containment procedures. The compound's aquatic toxicity classification necessitates particular attention to waste handling and disposal procedures. OYSI maintains availability of 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole for qualified industrial customers requiring this specialized chemical intermediate for legitimate commercial applications.

Safety & Classification

Danger
Classification:

Carc. 2; Acute Tox. 4; Acute Tox. 3; Eye Dam. 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H332

Harmful if inhaled.

H301

Toxic if swallowed.

H318

Causes serious eye damage.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2761
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameImazalil (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole?

1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole is an organic chemical compound with the molecular formula C14H14Cl2N2O and CAS number 35554-44-0. This substance has a molecular weight of 297.2 g/mol and contains both imidazole and dichlorophenyl functional groups. It is classified as a hazardous substance with multiple danger classes including carcinogenicity, acute toxicity, eye damage, and aquatic toxicity. The compound requires careful handling due to its significant health and environmental risks.

What are the physicochemical properties of 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole?

1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole is a complex organic molecule with a molecular weight of 297.2 g/mol. The compound contains chlorinated aromatic rings and imidazole functionality, which typically influence its solubility and stability properties. Due to the presence of dichlorophenyl groups, the substance likely exhibits limited water solubility but may be soluble in organic solvents. Specific physical properties such as melting point, boiling point, and density would require detailed analytical characterization for precise determination.

What is 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole used for?

1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole is primarily used as an intermediate in pharmaceutical and agrochemical synthesis. The imidazole ring system is commonly found in antifungal agents and other bioactive compounds. Given its structural features, this compound may serve as a building block for developing fungicides, pharmaceuticals, or other specialty chemicals. Its applications are typically limited to professional and industrial use due to its hazardous classification, requiring specialized handling and safety measures in manufacturing processes.

How to handle 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole safely?

Safe handling of 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole requires comprehensive personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Due to its carcinogenic potential (Carc. 2) and acute toxicity, minimize skin contact and avoid ingestion. Ensure proper training for personnel handling this substance and maintain emergency procedures readily available. Use appropriate engineering controls and follow established safety protocols for hazardous chemicals.

How to store 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole correctly?

Proper storage of 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole requires a cool, dry, well-ventilated area away from heat sources and direct sunlight. Store in tightly sealed, compatible containers to prevent contamination and moisture exposure. Given its hazardous classification, maintain separation from incompatible materials and ensure proper labeling with GHS pictogrammes (GHS08, GHS06, GHS05, GHS09). Implement restricted access controls and maintain inventory records. Storage areas should be equipped with appropriate spill containment measures and emergency response equipment.

What to do in case of contact with 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole?

In case of skin contact with 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention due to Eye Dam. 1 classification. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet for proper medical evaluation.

How to dispose of 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole appropriately?

Disposal of 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole must comply with local and national hazardous waste regulations due to its multiple danger classifications. The substance should be treated as hazardous waste and disposed of through licensed waste management facilities capable of handling carcinogenic and toxic materials. Incineration at appropriate high temperatures may be suitable, but requires proper emission controls due to chlorinated content. Never dispose of in regular waste streams or sewage systems due to its Aquatic Chronic 1 classification and environmental persistence.

How to transport 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole?

Transportation of 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole is regulated under ADR Class 6.1 (Toxic substances), Packing Group III. Packages must be properly labeled with appropriate hazard labels and shipping names according to dangerous goods regulations. Use UN-specification packaging suitable for Group III toxic liquids or solids. Transport vehicles must carry appropriate emergency equipment and documentation. Drivers require dangerous goods training certification. Ensure compliance with international transport regulations (ADR/RID for road/rail, IMDG for sea, ICAO for air transport).

Is 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole subject to specific regulations?

1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole is subject to multiple regulatory frameworks including REACH registration requirements in Europe and CLP classification obligations. While not currently listed as a Substance of Very High Concern (SVHC), its Carc. 2 classification may trigger additional regulatory scrutiny. The substance falls under dangerous goods transport regulations (ADR Class 6.1) and occupational safety legislation due to its hazardous properties. Manufacturers and importers must comply with safety data sheet requirements and notification procedures for carcinogenic substances.

Where to buy 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole in Europe?

1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole is available through OYSI, a specialized European distributor of chemical products with expertise in hazardous substances. As a professional chemical supplier, OYSI provides comprehensive documentation including safety data sheets, certificates of analysis, and regulatory compliance information. Given the substance's hazardous classification, purchase is typically restricted to qualified industrial users with appropriate handling capabilities. Contact OYSI directly for availability, technical specifications, and regulatory guidance for your specific application requirements in European markets.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.