Trioxochromium

CrO3

trioxochromium

CAS1333-82-0
GHS03 Gefahrensymbol: Brandfördernd – Flamme über Kreis
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
1333-82-0
EC Number
215-607-8
UN Number
1463
Index Number
024-001-00-0
PubChem CID
14915

Physical-chemical properties

Molecular Formula
CrO3
Molar Mass
99.99 g/mol
IUPAC Name
trioxochromium

Chemical Identifiers

InChI
InChI=1S/Cr.3O
InChI Key
WGLPBDUCMAPZCE-UHFFFAOYSA-N

Overview

Trioxochromium (CAS 1333-82-0) is a highly toxic hexavalent chromium compound with strong oxidizing properties and significant carcinogenic potential. Trioxochromium, also known as chromium trioxide, represents one of the most hazardous chromium compounds encountered in industrial applications. This dark red crystalline solid serves as a powerful oxidizing agent and finds extensive use across various industrial sectors despite its severe health risks. The compound's molecular structure consists of chromium in its highest oxidation state (+6), making it highly reactive and chemically aggressive. The substance poses multiple serious health hazards, classified as a Category 1A carcinogen, Category 1B mutagen, and Category 2 reproductive toxin. Its acute toxicity profile includes severe effects through inhalation, dermal contact, and ingestion routes. The compound's corrosive nature can cause severe burns to skin and eyes, while chronic exposure may lead to respiratory sensitization and organ damage. These properties are reflected in its ADR Class 5.1 classification as an oxidizing substance and the requirement for multiple GHS pictograms including oxidizing, health hazard, toxic, corrosive, and environmental hazard symbols. Industrial applications of trioxochromium include electroplating operations, where it serves as a chromium source for decorative and hard chrome plating processes. The compound also functions as a catalyst in organic synthesis reactions and finds use in specialized cleaning formulations for removing organic residues from glass and metal surfaces. Related compounds in the chromium family, such as disodium;oxido-(oxido(dioxo)chromio)oxy-dioxochromium and dipotassium;oxido-(oxido(dioxo)chromio)oxy-dioxochromium, share similar oxidizing properties but typically exhibit different solubility characteristics and handling requirements. OYSI maintains availability of trioxochromium for qualified industrial customers with appropriate handling capabilities and regulatory compliance frameworks.

Safety & Classification

Danger
Classification:

Ox. Sol. 1; Carc. 1A; Muta. 1B; Repr. 2; Acute Tox. 2 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE ...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H271

May cause fire or explosion; strong oxidiser.

H350

May cause cancer.

H340

May cause genetic defects.

H330

Fatal if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H372

Causes damage to organs through prolonged or repeated exposure.

H314

Causes severe skin burns and eye damage.

H334

May cause allergy or asthma symptoms or breathing difficulties if inhaled.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1463
ADR Class5.1
Packing GroupII
Tunnel CodeE
Proper Shipping NameChromtrioxid, wasserfrei
Marine PollutantNo

Frequently Asked Questions

What is trioxochromium?

Trioxochromium is a highly toxic inorganic compound with the chemical formula CrO3 and CAS number 1333-82-0. This chromium-based substance has a molecular weight of 99.994 g/mol and is classified as an extremely hazardous chemical with multiple danger classifications including carcinogenic, mutagenic, and reproductive toxicity properties. It requires strict handling procedures due to its severe health and environmental risks.

What are the physicochemical properties of trioxochromium?

Trioxochromium is a crystalline solid that appears as dark red or orange-red crystals or flakes. It is highly soluble in water, forming acidic solutions, and also dissolves in alcohols. The compound is hygroscopic, meaning it readily absorbs moisture from air. It has strong oxidizing properties and can react violently with organic materials and reducing agents, making it extremely reactive and dangerous to handle.

What is trioxochromium used for?

Trioxochromium is primarily used in industrial chrome plating processes, metal surface treatment, and as an oxidizing agent in various chemical reactions. It serves as a precursor for chromium-based catalysts and is utilized in the production of chromium compounds. Due to its extreme toxicity and carcinogenic properties, its use is heavily restricted and many applications have been replaced by safer alternatives where possible.

How to handle trioxochromium safely?

Trioxochromium requires extreme safety precautions including full respiratory protection with supplied air systems, chemical-resistant gloves, and complete body protection suits. Work must be conducted in well-ventilated areas or fume hoods with emergency shower facilities nearby. Avoid contact with organic materials, reducing agents, and moisture. Only trained personnel should handle this substance, and exposure monitoring is essential due to its carcinogenic and mutagenic properties.

How to store trioxochromium correctly?

Trioxochromium must be stored in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and incompatible materials. Keep containers tightly sealed and separate from organic materials, reducing agents, acids, and flammable substances. Storage areas should have appropriate containment systems and fire suppression equipment. Access must be restricted to authorized personnel only, with proper labeling and emergency response procedures in place.

What to do in case of contact with trioxochromium?

Trioxochromium exposure requires immediate emergency response due to its extreme toxicity. For skin contact, remove contaminated clothing and flush with copious amounts of water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical attention. For eye contact, rinse thoroughly with water. In all cases, seek immediate medical attention and inform healthcare providers about the specific substance and exposure circumstances.

How to dispose of trioxochromium appropriately?

Trioxochromium disposal must comply with strict hazardous waste regulations due to its classification as carcinogenic and toxic waste. It cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment facilities. Contact licensed waste disposal companies experienced with chromium compounds. Neutralization and stabilization may be required before disposal. Always follow local, national, and EU waste management regulations for hazardous substances.

How to transport trioxochromium?

Trioxochromium is classified under ADR Class 5.1 (Oxidizing substances) Packing Group II, requiring specialized transport procedures. It must be packaged in UN-approved containers with appropriate hazard labels and documentation. Transport vehicles need proper ventilation and emergency equipment. Only certified dangerous goods transporters can handle shipments, and specific routing restrictions may apply. Emergency response information must accompany all shipments.

Is trioxochromium subject to specific regulations?

Trioxochromium is subject to extensive European regulations under REACH and CLP due to its classification as carcinogenic (1A), mutagenic (1B), and reproductive toxin (category 2). It requires authorization for many uses and is subject to strict occupational exposure limits. Workers handling this substance need specialized training and health surveillance. Import, export, and use restrictions apply, with mandatory safety data sheets and risk assessments required.

Where to buy trioxochromium in Europe?

Trioxochromium is available through specialized chemical distributors like OYSI, which supplies high-quality chemical products across Europe. Due to its hazardous classification, purchases require proper documentation, end-use declarations, and compliance with regulatory requirements. OYSI provides technical support and ensures proper handling procedures are followed. Contact authorized distributors for availability, as this substance has restricted access and requires qualified personnel for procurement and handling.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.