Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is a synthetic pyrethroid insecticide, commonly known as cyhalothrin. This chemical compound has the molecular formula C22H19Cl2NO3 and a molecular weight of 416.3 g/mol. It belongs to the class of cyclopropane carboxylates and is characterized by its complex stereochemical structure with specific R and S configurations that determine its biological activity and effectiveness as a pest control agent.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is typically a colorless to pale yellow crystalline solid at room temperature. It has low water solubility but is soluble in organic solvents such as acetone, methanol, and toluene. The compound is relatively stable under normal conditions but may decompose under extreme heat or alkaline conditions. Its molecular structure contains chlorine atoms and aromatic rings, contributing to its lipophilic nature and biological activity.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is primarily used as an active ingredient in insecticidal formulations. It serves as a broad-spectrum insecticide for agricultural crop protection, controlling various pests including lepidopteran larvae, aphids, and other harmful insects. The compound is also utilized in professional pest control applications for structural pest management. Its high potency and relatively low application rates make it valuable in integrated pest management programs across different agricultural and horticultural sectors.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate requires careful handling with appropriate personal protective equipment. Wear chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Use respiratory protection in poorly ventilated areas to avoid inhalation. Work in well-ventilated spaces and avoid eating, drinking, or smoking during handling. Wash hands thoroughly after use. The substance is classified as Acute Tox. 4, Skin Irrit. 2, and Skin Sens. 1, requiring precautions against dermal exposure and sensitization.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed and protected from moisture to prevent degradation. Store away from incompatible materials such as strong bases, oxidizing agents, and food products. Maintain storage temperatures below 25°C when possible. Ensure storage areas are equipped with appropriate containment measures and are accessible only to authorized personnel. Regular inspection of containers for damage or leaks is recommended.

Immediate action is required upon contact with trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. If swallowed, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet when seeking medical treatment.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate must be disposed of through authorized hazardous waste disposal facilities. The substance cannot be discharged to sewers, waterways, or regular municipal waste due to its classification as Aquatic Acute 1 and Aquatic Chronic 1. Contact licensed waste management companies for proper collection and treatment. Empty containers should also be handled as hazardous waste. Follow local, national, and EU regulations for hazardous waste disposal. Incineration at high temperatures in approved facilities is typically the preferred disposal method.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is classified under ADR Class 6.1, Packing Group III for transport purposes. It must be shipped as a toxic substance requiring appropriate dangerous goods packaging, labeling, and documentation. Packages must bear proper shipping names, UN numbers, and hazard labels. Transport vehicles require proper placarding and emergency information. Only certified carriers with dangerous goods authorization should handle shipment. Special precautions are needed to prevent release during transport, and emergency response procedures must be readily available.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is subject to comprehensive EU chemical regulations. It falls under REACH regulation requiring registration and compliance with substance identification and safety requirements. CLP classification applies with mandatory hazard labeling showing GHS07 and GHS09 pictograms and 'Warning' signal word. The substance is regulated under biocide and plant protection product legislation. Although not currently listed as SVHC, regulatory status should be monitored regularly as classifications can change based on new scientific evidence.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this substance to qualified industrial customers with proper handling capabilities and regulatory compliance. As a controlled substance requiring specialized handling, purchases are restricted to authorized users with appropriate licenses and facilities. Contact OYSI directly for availability, technical specifications, and regulatory documentation. All sales comply with European chemical distribution regulations and require proper end-use verification.