Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is a synthetic pyrethroid insecticide with the molecular formula C22H19Cl2NO3 and CAS number 67375-30-8. This compound has a molecular weight of 416.3 g/mol and belongs to the cyclopropane carboxylate family of pesticides, characterized by its complex stereochemical structure containing phenoxy and cyano functional groups.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is typically a crystalline solid at room temperature with low water solubility. The compound exhibits stability under normal conditions but may decompose under extreme heat or UV exposure. Its lipophilic nature allows good penetration through biological membranes, which is essential for its pesticidal activity. The presence of chlorine atoms and aromatic rings contributes to its persistence and bioactivity.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is primarily used as an active ingredient in insecticidal formulations for agricultural and pest control applications. It serves as a broad-spectrum insecticide effective against various flying and crawling insects. The compound is incorporated into professional pest control products, agricultural sprays, and household insecticides due to its potent neurotoxic effects on target insects while maintaining relatively lower mammalian toxicity.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas to minimize inhalation exposure. Avoid skin and eye contact due to its irritant properties and potential for sensitization. Use proper handling techniques to prevent spills and ensure immediate cleanup of any accidental releases to protect the aquatic environment.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly sealed and store separately from food, feed, and incompatible materials. Due to its aquatic toxicity classification, ensure storage areas have appropriate containment measures to prevent environmental contamination. Maintain storage temperature below 25°C and protect from moisture to preserve product stability and prevent degradation.

In case of skin contact with trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water. For eye contact, rinse immediately with plenty of clean water for at least 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention if symptoms persist or worsen, especially given the compound's acute toxicity classification. Do not induce vomiting if ingested and contact poison control immediately.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate must be disposed of through licensed hazardous waste disposal facilities due to its toxic and environmentally hazardous properties. Never dispose of this substance in regular waste streams, sewers, or waterways given its acute and chronic aquatic toxicity. Contaminated packaging should also be treated as hazardous waste. Consult local environmental authorities for specific disposal requirements and approved waste management contractors in your region.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is classified as ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. Packages must be properly labeled with appropriate hazard labels and shipping names. Transport vehicles should be equipped with appropriate safety equipment and drivers must have proper training for toxic substance transport. Ensure packages are secured to prevent damage during transit and have emergency response information readily available.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is subject to REACH regulation for chemical registration and CLP regulation for classification and labeling in the European Union. The substance is not currently listed as an SVHC (Substance of Very High Concern). As a pesticide active ingredient, it may also be subject to biocidal product regulations and plant protection product legislation, requiring specific authorizations for commercial use in pest control formulations.

Trans-[(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound to qualified industrial customers, research institutions, and pesticide manufacturers across Europe. Due to its toxic properties and regulatory requirements, purchase is typically restricted to licensed professionals in the pest control, agricultural, or chemical manufacturing industries who can demonstrate proper handling capabilities and intended use compliance.